Search Results - "Lehman, L"

The ubiquitin proteasome system in neuropathology by Lehman, Norman L.

“…The ubiquitin proteasome system (UPS) orchestrates the turnover of innumerable cellular proteins. In the process of ubiquitination the small protein ubiquitin…”
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miRDeep: an integrated application tool for miRNA identification from RNA sequencing data by An, Jiyuan, Lai, John, Lehman, Melanie L, Nelson, Colleen C

“…miRDeep and its varieties are widely used to quantify known and novel micro RNA (miRNA) from small RNA sequencing (RNAseq). This article describes miRDeep*,…”
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Biodiversity, Stability, and Productivity in Competitive Communities by Lehman, Clarence L., Tilman, David

“…Three markedly different models of multispecies competition—one mechanistic, one phenomenological, and one statistical—all predict that greater diversity…”
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Cyclic twin nucleation in tin-based solder alloys by Lehman, L.P., Xing, Y., Bieler, T.R., Cotts, E.J.

“…The microstructure and Sn crystal orientations of lead-free solder alloys such as near-eutectic SnAgCu have a significant influence on the mechanical response…”
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miRPlant: an integrated tool for identification of plant miRNA from RNA sequencing data by An, Jiyuan, Lai, John, Sajjanhar, Atul, Lehman, Melanie L, Nelson, Colleen C

“…Small RNA sequencing is commonly used to identify novel miRNAs and to determine their expression levels in plants. There are several miRNA identification tools…”
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Perinatal Arterial Ischemic Stroke: Presentation, Risk Factors, Evaluation, and Outcome by Lehman, Laura L., MD, Rivkin, Michael J., MD

“…Abstract Background Perinatal arterial ischemic stroke is as common as large vessel arterial ischemic stroke in adults and leads to significant morbidity…”
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Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development by QIAN WANG, TIFFEN, Jessamy, BUCHANAN, Grant, NELSON, Colleen C, RASKO, John E. J, HOLST, Jeff, BAILEY, Charles G, LEHMAN, Melanie L, RITCHIE, William, FAZLI, Ladan, METIERRE, Cynthia, YUE FENG, LI, Estelle, GLEAVE, Martin

“…L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling…”
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CX-5461 induces radiosensitization through modification of the DNA damage response and not inhibition of RNA polymerase I by Lehman, Stacey L., Schwartz, Kayla R., Maheshwari, Shrankhla, Camphausen, Kevin, Tofilon, Philip J.

“…Increased ribosome biogenesis is a distinguishing feature of cancer cells, and small molecule inhibitors of ribosome biogenesis are currently in clinical…”
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PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance by Russell, Luke, Swanner, Jessica, Jaime-Ramirez, Alena Cristina, Wang, Yufeng, Sprague, Alex, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Sizemore, Gina M., Kladney, Raleigh, Zhang, Jianying, Lehman, Norman L., Ostrowski, Michael C, Hong, Bangxing, Caligiuri, Michael, Yu, Jianhua, Kaur, Balveen

“…Engineered oncolytic viruses are used clinically to destroy cancer cells and have the ability to boost anticancer immunity. Phosphatase and tensin homolog…”
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Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination by Zhao, Liang, Wang, Chenwei, Lehman, Melanie L., He, Mingyu, An, Jiyuan, Svingen, Terje, Spiller, Cassy M., Ng, Ee Ting, Nelson, Colleen C., Koopman, Peter

“…Mammalian sex determination hinges on sexually dimorphic transcriptional programs in developing fetal gonads. A comprehensive view of these programs is crucial…”
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Phylogenetic and experimental evidence for host-specialized cryptic species in a biotrophic oomycete by Rouxel, Mélanie, Mestre, Pere, Comont, Gwenaelle, Lehman, Brian L., Schilder, Annemiek, Delmotte, François

“…Assortative mating resulting from host plant specialization has been proposed to facilitate rapid ecological divergence in biotrophic plant pathogens. Downy…”
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Axonal Outgrowth and Dendritic Plasticity in the Cortical Peri-Infarct Area After Experimental Stroke by YUJI UENO, CHOPP, Michael, LI ZHANG, BULLER, Benjamin, ZHONGWU LIU, LEHMAN, Norman L, XIAN SHUANG LIU, YI ZHANG, ROBERTS, Cynthia, ZHENG GANG ZHANG

“…Axonal remodeling is critical to brain repair after stroke. The present study investigated axonal outgrowth after stroke and the signaling pathways mediating…”
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Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression by QIAN WANG, BAILEY, Charles G, RASKO, John E. J, HOLST, Jeff, NG, Cynthia, TIFFEN, Jessamy, THOENG, Annora, MINHAS, Vineet, LEHMAN, Melanie L, HENDY, Stephen C, BUCHANAN, Grant, NELSON, Colleen C

“…L-Type amino acid transporters such as LAT1 and LAT3 mediate the uptake of essential amino acids. Here, we report that prostate cancer cells coordinate the…”
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Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment by Sieh, Shirly, Taubenberger, Anna V, Rizzi, Simone C, Sadowski, Martin, Lehman, Melanie L, Rockstroh, Anja, An, Jiyuan, Clements, Judith A, Nelson, Colleen C, Hutmacher, Dietmar W

“…Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in…”
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Central Nervous System Tumors With Ependymal Features: A Broadened Spectrum of Primarily Ependymal Differentiation? by Lehman, Norman L

“…Ependymomas are well-characterized central nervous system (CNS) tumors that occur most often in children and young adults. Several other CNS tumor entities,…”
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A Review of Scrub Typhus (Orientia tsutsugamushi and Related Organisms): Then, Now, and Tomorrow by Luce-Fedrow, Alison, Lehman, Marcie L, Kelly, Daryl J, Mullins, Kristin, Maina, Alice N, Stewart, Richard L, Ge, Hong, John, Heidi St, Jiang, Ju, Richards, Allen L

“…Scrub typhus and the rickettsial diseases represent some of the oldest recognized vector-transmitted diseases, fraught with a rich historical aspect,…”
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Translation Initiation Machinery as a Tumor Selective Target for Radiosensitization by Lehman, Stacey L., Wilson, Evan D., Camphausen, Kevin, Tofilon, Philip J.

“…Towards improving the efficacy of radiotherapy, one approach is to target the molecules and processes mediating cellular radioresponse. Along these lines,…”
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Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma by Lehman, Stacey L., Ryeom, Sandra, Koumenis, Constantinos

“…The tumor microenvironment is characterized by deficiencies in oxygen and nutrients, such as glucose and amino acids. Activation of the GCN2 arm of the…”
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Leukoaraiosis and Sex Predict the Hyperacute Ischemic Core Volume by HENNINGER, Nils, LIN, Eugene, HAUSSEN, Diogo C, LEHMAN, Laura L, TAKHTANI, Deepak, SELIM, Magdy, MOONIS, Majaz

“…Leukoaraiosis (LA) and male sex have been associated with decreased cerebrovascular reactivity, which potentially adversely affects tissue viability in acute…”
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Molecular diagnosis of sepsis: New aspects and recent developments by Liesenfeld, O, Lehman, L, Hunfeld, K-P, Kost, G

“…By shortening the time to pathogen identification and allowing for detection of organisms missed by blood culture, new molecular methods may provide clinical…”
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