Search Results - "Leheste, Joerg R"

The cannabidiol and marijuana research expansion act: Promotion of scientific knowledge to prevent a national health crisis by Purcell, John M., Passley, Tija M., Leheste, Joerg R.

“…While the use of medical and recreational cannabis is rapidly expanding under state jurisdiction, the convolution of federal regulations is obstructing…”
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Perspectives of Pitocin administration on behavioral outcomes in the pediatric population: recent insights and future implications by Torres, German, Mourad, Mervat, Leheste, Joerg R.

“…Oxytocin plays an important role in the regulation of parturition as this peptide hormone promotes uterine smooth muscle contractility in gravid women…”
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Managing Addiction and Overdose Deaths: The Debate Over America's Safe Injection Spaces by Rasool, Farhaad, Klein, Arthur A, Leheste, Joerg R

“…In the decade between 2010 and 2020, the number of people killed by opioid overdoses more than tripled, reaching 68,630. Among drug users in their second and…”
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Preliminary Effects of Osteopathic Manipulative Medicine on Reactive Oxygen Species in Parkinson's Disease: A Randomized Controlled Pilot Study by Docherty, James, Leheste, Joerg R, Mancini, Jayme, Yao, Sheldon

“…Context Parkinson's disease (PD) is the second most common neurodegenerative disorder and causes many clinical manifestations including bradykinesia, tremor,…”
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Indoor Air Pollution and Decision-Making Behavior: An Interdisciplinary Review by Torres, German, Mourad, Mervat, Leheste, Joerg R

“…The human brain is constantly exposed to air pollutants, some of which might be disruptive or even lethal to certain neurons implicated in abstract features of…”
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Conceptualizing Epigenetics and the Environmental Landscape of Autism Spectrum Disorders by Torres, German, Mourad, Mervat, Iqbal, Saba, Moses-Fynn, Emmanuel, Pandita, Ashani, Siddhartha, Shriya S, Sood, Riya A, Srinivasan, Kavya, Subbaiah, Riya T, Tiwari, Alisha, Leheste, Joerg R

“…Complex interactions between gene variants and environmental risk factors underlie the pathophysiological pathways in major psychiatric disorders. Autism…”
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Ketamine intervention limits pathogen expansion in vitro by Torres, German, Hoehmann, Christopher L, Cuoco, Joshua A, Hitscherich, Kyle, Pavia, Charles, Hadjiargyrou, Michael, Leheste, Joerg R

“…Ketamine is one of several clinically important drugs whose therapeutic efficacy is due in part to their ability to act upon ion channels prevalent in nearly…”
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A behavioral and molecular analysis of ketamine in zebrafish by Zakhary, Sherry M., Ayubcha, Diana, Ansari, Farah, Kamran, Kiran, Karim, Mehwish, Leheste, Joerg R., Horowitz, Judith M., Torres, German

“…Ketamine exerts powerful anesthetic, psychotic, and antidepressant effects in both healthy volunteers and clinically depressed patients. Although ketamine…”
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P. acnes -Driven Disease Pathology: Current Knowledge and Future Directions by Leheste, Joerg R, Ruvolo, Kathryn E, Chrostowski, Joanna E, Rivera, Kristin, Husko, Christopher, Miceli, Alyssa, Selig, Martin K, Brüggemann, Holger, Torres, German

“…This review discusses the biology and behavior of ( ), a dominant bacterium species of the skin biogeography thought to be associated with transmission,…”
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Distribution Analysis of Deacetylase SIRT1 in Rodent and Human Nervous Systems by Zakhary, Sherry M., Ayubcha, Diana, Dileo, Jeffery N., Jose, Riya, Leheste, Joerg R., Horowitz, Judith M., Torres, German

“…Sirtuins function with other biogenic molecules to promote adaptation to caloric restriction in a broad spectrum of eukaryotic species. Sirtuin pathways also…”
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Central and Peripheral Expression of DNA Double‐Strand Breaks in Human and Mouse Tissues by Castiglione, Mia P., Ramos, Raddy L., Leheste, Joerg R., Torres, German

“…ABSTRACT Mammalian cells accumulate DNA lesions when they undergo phases of the cell cycle or during normal cellular activity. In this regard, several DNA…”
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Health Equity in a Post 'Roe Versus Wade' America by Byron, Jessica J, Avalos, Melba, Xiao, Kexin Amy, Klein, Arthur A, Leheste, Joerg R

“…For almost five decades, the US Supreme Court had protected the right to abortion care in the United States. However, the Court's decision in 'Dobbs versus…”
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Resveratrol: brain effects on SIRT1, GPR50 and photoperiodic signaling by Leheste, Joerg R, Torres, German

“…Silent information regulator-1 (SIRT1) deacetylase, a sensor of intermittent energy restriction, is inextricably intertwined with circadian regulation of…”
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An Evolutionary Perspective of Neoplastic Diseases in the Universe by Torres, German, Zakhary, Sherry M, Leheste, Joerg R

“…The existence of exoplanets orbiting low mass-stars is one of the most significant discoveries of our time. Especially intriguing to us is the possibility that…”
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Linking Brain Arteriovenous Malformations With Anorectal Hemorrhoids: A Clinical and Anatomical Review by Cuoco, Joshua A., Hoehmann, Christopher L., Hitscherich, Kyle, Zakhary, Sherry M., Leheste, Joerg R., Torres, German

“…ABSTRACT Patients who harbor brain arteriovenous malformations are at risk for intracranial hemorrhage. These malformations are often seen in inherited…”
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The Glymphatic-Lymphatic Continuum: Opportunities for Osteopathic Manipulative Medicine by Hitscherich, Kyle, Smith, Kyle, Cuoco, Joshua A, Ruvolo, Kathryn E, Mancini, Jayme D, Leheste, Joerg R, Torres, German

“…The brain has long been thought to lack a lymphatic drainage system. Recent studies, however, show the presence of a brain-wide paravascular system…”
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Neurodevelopmental Malformations of the Cerebellar Vermis in Genetically Engineered Rats by Ramos, Raddy L., Van Dine, Sarah E., Gilbert, Mary E., Leheste, Joerg R., Torres, German

“…The cerebellar vermis is particularly vulnerable to neurodevelopmental malformations in humans and rodents. Sprague–Dawley, and Long–Evans rats exhibit…”
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Molecular layer heterotopia of the cerebellar vermis in mutant and transgenic mouse models on a C57BL/6 background by Ramos, Raddy L, Van Dine, Sarah E, George, Elizabeth, Patel, Dhruv, Hoplight, Blair J, Leheste, Joerg R, Richfield, Eric K, Torres, German

“…Highlights • Mutant mice on a C57BL/6 background exhibit cerebellar heterotopia. • Cre-transgenic mice on a C57BL/6 background exhibit cerebellar heterotopia…”
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A ChIP-cloning approach linking SIRT1 to transcriptional modificationof DNA targets by Torres, German, Frisella, Patrick D, Yousuf, Salman J, Sarwar, Samina, Baldinger, Lauren, Zakhary, Sherry M, Leheste, Joerg R

“…The mammalian protein deacetylase SIRT1 (sirtuin1) is widely recognized for its link to calorie restriction and longevity. SIRT1 not only modulates the…”
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Caenorhabditis elegans as an undergraduate educational tool for teaching RNAi by Andersen, Janet, Krichevsky, Alexander, Leheste, Joerg R., Moloney, Daniel J.

“…Discovery of RNA‐mediated interference (RNAi) is widely recognized as one of the most significant molecular biology breakthroughs in the past 10 years. There…”
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