Search Results - "Lehel, Csaba"
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Habitat use and population biology of the Danube Clouded Yellow butterfly Colias myrmidone (Lepidoptera: Pieridae) in Romania
Published in Journal of insect conservation (01-06-2014)“…The Danube Clouded Yellow (Colias myrmidone) is one of the most endangered butterflies in Europe. Its distribution range shrank dramatically in the last few…”
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2
Interactions between Protein Kinase C and Pleckstrin Homology Domains
Published in The Journal of biological chemistry (16-05-1997)“…Pleckstrin homology (PH) domains comprised of loosely conserved sequences of ∼100 amino acid residues are a functional protein motif found in many…”
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3
Protein Kinase C Subcellular Localization Domains and Proteolytic Degradation Sites
Published in The Journal of biological chemistry (18-08-1995)“…Protein kinase C (PKC) has been found to have unique properties among the PKC isozymes in terms of its membrane association, oncogenic potential, and substrate…”
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4
Heat shock protein synthesis of the cyanobacterium Synechocystis PCC 6803: purification of the GroEL-related chaperonin
Published in Plant molecular biology (01-01-1992)“…Synechocystis PCC 6803 cells could be induced to synthesize four major HSPs with apparent molecular sizes of 70, 64, 15 and 14 kDa. Heat stress at 42.5 degrees…”
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5
A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit
Published in Bioorganic & medicinal chemistry letters (01-01-2011)“…A novel series of thiosemicarbazides was discovered as potent inhibitors of IKKβ. A novel series of (E)-1-((2-(1-methyl-1H-imidazol-5-yl) quinolin-4-yl)…”
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6
A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs
Published in Bioorganic & medicinal chemistry letters (01-01-2011)“…Compound 2 was the culmination of SAR efforts from HTS lead 1. It has submicromolar potency in a HWB assay and efficacy in a CIA mouse model. A novel series of…”
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7
The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter
Published in The Journal of biological chemistry (14-10-1994)“…The primate type C retrovirus gibbon ape leukemia virus (GaLV) has been shown to use a widely expressed, multiple membrane-spanning protein of unknown function…”
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8
Protein Kinase Cε is Localized to the Golgi Via Its Zinc-Finger Domain and Modulates Golgi Function
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-1995)“…Protein kinase C (PKC) is a multigene family of serine/threonine kinases that are central to many signal transduction pathways. Among the PKC isozymes, only…”
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9
A Chemiluminescent Microtiter Plate Assay for Sensitive Detection of Protein Kinase Activity
Published in Analytical biochemistry (15-01-1997)“…A chemiluminescent protein kinase assay using biotinylated substrate peptides captured on a streptavidin-coated microtiter plate and monoclonal antibodies to…”
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10
Protein kinase Cepsilon mediates PMA-induced growth inhibition of low population density NIH 3T3 fibroblasts
Published in Archives of biochemistry and biophysics (15-01-2002)“…Phorbol 12-myristate-13-acetate (PMA), a potent tumor promoter and activator of most protein kinase C (PKC) isotypes, was found to significantly inhibit the…”
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11
Protein kinase C epsilon subcellular localization domains and proteolytic degradation sites. A model for protein kinase C conformational changes
Published in The Journal of biological chemistry (18-08-1995)“…Protein kinase C (PCK) epsilon has been found to have unique properties among the PCK isozymes in terms of its membrane association, oncogenic potential, and…”
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12
Protein Kinase Cϵ Mediates PMA-Induced Growth Inhibition of Low Population Density NIH 3T3 Fibroblasts
Published in Archives of biochemistry and biophysics (15-01-2002)“…Phorbol 12-myristate-13-acetate (PMA), a potent tumor promoter and activator of most protein kinase C (PKC) isotypes, was found to significantly inhibit the…”
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13
Overexpression of Protein Kinase C-ε and Its Regulatory Domains in Fibroblasts Inhibits Phorbol Ester-Induced Phospholipase D Activity
Published in Archives of biochemistry and biophysics (01-03-1999)“…In fibroblasts, the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) stimulates phospholipase D (PLD)-mediated hydrolysis of both…”
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14
Development of a Rapid Approach to Identification of Tyrosine Phosphorylation Sites: Application to PKCδ Phosphorylated upon Activation of the High Affinity Receptor for IgE in Rat Basophilic Leukemia Cells
Published in Biochemical and biophysical research communications (25-09-1995)“…In rat basophilic leukemia cells (RBL-2H3) activation of the high affinity receptor for IgE induces tyrosine phosphorylation of PKCδ. We carried out solid…”
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15
The dual-function hamster receptor for amphotropic murine leukemia virus (MuLV), 10A1 MuLV, and gibbon ape leukemia virus is a phosphate symporter
Published in Journal of Virology (01-01-1995)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Protein kinase Cepsilon is localized to the Golgi via its zinc-finger domain and modulates Golgi function
Published in Proceedings of the National Academy of Sciences - PNAS (28-02-1995)“…NIH 3T3 cells were stably transfected to overexpress different epitope-tagged fragments of protein kinase C (PKC) epsilon to examine the interrelationship…”
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17
Influence of Various Domains of Protein Kinase C ϵ on Its PMA-Induced Translocation from the Golgi to the Plasma Membrane
Published in Biochemical and biophysical research communications (05-06-1996)“…Subcellular redistribution (translocation) was initiated by treatment of NIH 3T3 cells overexpressing different epitope-tagged fragments of PKCϵ with PMA, and…”
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18
A second groEL-like gene, organized in a groESL operon is present in the genome of Synechocystis sp. PCC 6803
Published in The Journal of biological chemistry (25-01-1993)“…Using a groEL gene of Synechococcus sp. PCC 7942 as a DNA probe, a 4.8-kilobase pair (kbp) BamHI fragment of chromosomal DNA of Synechocystis sp. PCC 6803 was…”
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19
The 33-kDa C-Terminal Domain of Raf-1 Protein Kinase Exhibits a RAS-Independent Serum- and Phorbol Ester-Induced Shift in Gel Mobility
Published in Biochemical and biophysical research communications (14-09-1995)“…Experiments were carried out to determine Raf-1 protein kinase domain fragments which exhibit a characteristic electrophoretic mobility shift noted with Raf-1…”
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20
Differential effects of activation of protein kinase C and cyclic-AMP-dependent protein kinase on sodium-dependent phosphate uptake in NIH 3T3 cells
Published in Biochimica et biophysica acta (16-04-1993)“…Activation of protein kinase C (PKC) by phorbol ester (PMA), or by diacylglycerol analogue (OAG) treatment of NIH 3T3 cells resulted in the rapid (within 2-5…”
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