Search Results - "Legutko, B."
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Antidepressant-mediated reversal of abnormal behavior and neurodegeneration in mice following olfactory bulbectomy
Published in Experimental neurology (01-03-2007)“…Olfactory bulbectomy is an established animal model of depression that has been mostly investigated in rats. As in human major depression, bulbectomy induces…”
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Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator
Published in Neuropharmacology (01-06-2001)“…The effects of a novel AMPA receptor potentiator (LY392098) on the expression of brain-derived neurotrophic factor (BDNF) were examined in primary neuron…”
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Roles of exogenous and endogenous FGF-2 in animal models of depression
Published in Restorative neurology and neuroscience (2011)“…Several members of the fibroblast growth factor (FGF) family have been shown to be dysregulated in individuals with major depression, and treatment with…”
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Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-06-2007)“…The problem of drug-resistant depression indicates a strong need for alternative antidepressant therapies. In our earlier papers we described synergistic,…”
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Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity
Published in Diabetes (New York, N.Y.) (01-10-2017)“…Neuronal circuits in the brain help to control feeding behavior and systemic metabolism in response to afferent nutrient and hormonal signals. Although…”
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The development of neuropeptide Y-immunoreactive neurons in a model of pure cortical culture
Published in Neuroscience (01-12-1992)“…The development of neuropeptide Y-immunoreactive neurons in the rat brain cerebral cortex was studied in a model of a pure cortical culture. In this model,…”
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Influence of imipramine on neuropeptide Y immunoreactivity in the rat brain
Published in Neuroscience (1991)“…The effects of treatment with the antidepressant drug imipramine on neuropeptide Y immunoreactivity were studied immunocytochemically in the rat brain cortex…”
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Haloperidol-induced increase in neuropeptide Y immunoreactivity in the locus coeruleus of the rat brain
Published in Neuroscience (1992)“…The effect of haloperidol, a dopamine (preferably D2) receptor blocking agent on neuropeptide Y immunoreactivity was studied immunohistochemically in neurons…”
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Influence of reserpine administration on neuropeptide Y immunoreactivity in the locus coeruleus and caudate-putamen nucleus of the rat brain
Published in Neuroscience (1990)“…The effects of treatment with reserpine (10 mg/kg, i.p.) a monoamine depleting agent, on neuropeptide Y immunoreactivity were studied immunohistochemically in…”
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Combined treatment with imipramine and metyrapone induces hippocampal and cortical brain-derived neurotrophic factor gene expression in rats
Published in Pharmacological reports (01-11-2005)“…The problem of drug-resistant depression indicates a strong need for alternative antidepressant therapies. Recently it was shown that joint administration of…”
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Zinc treatment induces cortical brain-derived neurotrophic factor gene expression
Published in European journal of pharmacology (10-05-2004)“…Most of antidepressants induce expression of the gene coding for brain-derived neurotrophic factor (BDNF) in the hippocampal/cortical neurons. Recent data…”
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Current perspectives on the development of non-biogenic amine-based antidepressants
Published in Pharmacological research (01-05-2001)“…Compounds that inhibit the re-uptake and/or metabolism of biogenic amines (i.e. serotonin, norepinephrine, and dopamine) have been used to treat depression for…”
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Repeated treatment with mirtazepine induces brain-derived neurotrophic factor gene expression in rats
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-12-2005)“…Recent studies indicate a role of the brain-derived neurotrophic factor (BDNF) in the pathophysiology of depression, as well as in the mechanism of action of…”
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Antidepressant treatment influences cyclic AMP accumulation induced by excitatory amino acids in rat brain
Published in Polish journal of pharmacology (01-07-1995)“…The prolonged imipramine or electroconvulsive shock treatment induced a decrease in ibotenate stimulated increase in cyclic AMP accumulation as well as it…”
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Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors
Published in European journal of pharmacology (26-01-1998)“…Glycine displaces [ 3 H ]CGP-39653 ([ 3 H ] d, l-(E)-2-amino-4-propyl-5-phosphono-3-pentenoic acid) binding to the glutamate recognition site with both high…”
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P45 CHRONIC CO-TREATMENT WITH ANTIDEPRESSANT DRUGS AND AMANTADINE INDUCES BDNF GENE EXPRESSION IN RATS
Published in Behavioural pharmacology (01-09-2006)Get full text
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The enhancement and the inhibition of noradrenaline-induced cyclic AMP accumulation in rat brain by stimulation of metabotropic glutamate receptors
Published in Acta physiologica Hungarica (1996)“…The actions of several metabotropic glutamate receptor agonists and antagonists on noradrenaline (NA)-stimulated [3H]-cyclic AMP accumulation were investigated…”
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P46 FGF-2 ATTENUATES NEURODEGENERATION AND BEHAVIORAL DYSFUNCTIONS FOLLOWING OLFACTORY BULBECTOMY IN MICE
Published in Behavioural pharmacology (01-09-2006)Get full text
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The effect of interaction between (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R)-ACPD and noradrenaline on cyclic AMP accumulation: different actions in brain slices, primary glial and neuronal cell cultures
Published in Polish journal of pharmacology (01-01-1995)“…The existence of multiple metabotropic receptors for excitatory amino acids is firmly established by recent cloning experiments. Several subtypes of those…”
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