Search Results - "Legras, Antoine"

Clinical assessment of the miR-34, miR-200, ZEB1 and SNAIL EMT regulation hub underlines the differential prognostic value of EMT miRs to drive mesenchymal transition and prognosis in resected NSCLC by Garinet, Simon, Didelot, Audrey, Denize, Thomas, Perrier, Alexandre, Beinse, Guillaume, Leclere, Jean-Baptiste, Oudart, Jean-Baptiste, Gibault, Laure, Badoual, Cecile, Le Pimpec-Barthes, Françoise, Laurent-Puig, Pierre, Legras, Antoine, Blons, Helene

“…Background Patients with non-small cell lung cancer (NSCLC) receiving curative surgery have a risk of relapse, and adjuvant treatments only translate into a 5%…”
Get full text

Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma by Zhang, Tuo, Sun, Beibei, Zhong, Chenxi, Xu, Ke, Wang, Zhexin, Hofman, Paul, Nagano, Tatsuya, Legras, Antoine, Breadner, Daniel, Ricciuti, Biagio, Divisi, Duilio, Schmid, Ralph A., Peng, Ren-Wang, Yang, Haitang, Yao, Feng

Get full text

Epithelial-to-Mesenchymal Transition and MicroRNAs in Lung Cancer by Legras, Antoine, Pécuchet, Nicolas, Imbeaud, Sandrine, Pallier, Karine, Didelot, Audrey, Roussel, Hélène, Gibault, Laure, Fabre, Elizabeth, Le Pimpec-Barthes, Françoise, Laurent-Puig, Pierre, Blons, Hélène

“…Despite major advances, non-small cell lung cancer (NSCLC) remains the major cause of cancer-related death in developed countries. Metastasis and drug…”
Get full text

High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition by Tavernier, Quentin, Legras, Antoine, Didelot, Audrey, Normand, Corinne, Gibault, Laure, Badoual, Cécile, Le Pimpec-Barthes, Françoise, Puig, Pierre Laurent, Blons, Hélène, Pallet, Nicolas

“…Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor growth and aggressiveness. Endoplasmic Reticulum (ER) stress has been…”
Get full text

A novel Chr1-miR-200 driven whole transcriptome signature shapes tumor immune microenvironment and predicts relapse in early-stage lung adenocarcinoma by Garinet, Simon, Didelot, Audrey, Marisa, Laetitia, Beinse, Guillaume, Sroussi, Marine, Le Pimpec-Barthes, Françoise, Fabre, Elizabeth, Gibault, Laure, Laurent-Puig, Pierre, Mouillet-Richard, Sophie, Legras, Antoine, Blons, Hélène

“…In Lung adenocarcinoma (LUAD), targeted therapies and immunotherapies have moved from metastatic to early stage and stratification of the relapse risk becomes…”
Get full text

Long-Term Survival of Patients With pN2 Lung Cancer According to the Pattern of Lymphatic Spread by Legras, Antoine, MD, Mordant, Pierre, MD, PhD, Arame, Alex, MD, Foucault, Christophe, MD, Dujon, Antoine, MD, Le Pimpec Barthes, Françoise, MD, PhD, Riquet, Marc, MD, PhD

“…Background N2 involvement has dramatic consequences on the prognosis and management of patients with non-small cell lung cancer (NSCLC). N2-NSCLC may present…”
Get full text

Number of Mediastinal Lymph Nodes in Non-Small Cell Lung Cancer: A Gaussian Curve, Not a Prognostic Factor by Riquet, Marc, MD, PhD, Legras, Antoine, MD, Mordant, Pierre, MD, PhD, Rivera, Caroline, MD, Arame, Alex, MD, Gibault, Laure, MD, Foucault, Christophe, MD, Dujon, Antoine, MD, Le Pimpec Barthes, Françoise, MD, PhD

“…Background It has been proposed that examining a greater number of lymph nodes (LNs) in patients with non–small-cell lung cancer (NSCLC) treated by surgical…”
Get full text

Pneumothorax Recurrence After Surgery in Women: Clinicopathologic Characteristics and Management by Alifano, Marco, MD, PhD, Legras, Antoine, MD, Rousset-Jablonski, Christine, MD, Bobbio, Antonio, MD, PhD, Magdeleinat, Pierre, MD, Damotte, Diane, MD, PhD, Roche, Nicolas, MD, PhD, Regnard, Jean-François, MD

“…Background Our aim was to study the clinical, surgical, and pathological characteristic of women with homolateral recurrence of pneumothorax despite previous…”
Get full text

Impact of surgical approach on 90-day mortality after lung resection for nonsmall cell lung cancer in high-risk operable patients by Etienne, Harry, Pagès, Pierre-Benoît, Iquille, Jules, Falcoz, Pierre Emmanuel, Brouchet, Laurent, Berthet, Jean-Philippe, Le Pimpec Barthes, Françoise, Jougon, Jacques, Filaire, Marc, Baste, Jean-Marc, Anne, Valentine, Renaud, Stéphane, D'Annoville, Thomas, Meunier, Jean Pierre, Jayle, Christophe, Dromer, Christian, Seguin-Givelet, Agathe, Legras, Antoine, Rinieri, Philippe, Jaillard-Thery, Sophie, Margot, Vincent, Thomas, Pascal-Alexandre, Dahan, Marcel, Mordant, Pierre

“…Non-small cell lung cancer (NSCLC) is often associated with compromised lung function. Real-world data on the impact of surgical approach in NSCLC patients…”
Get full text

Fate of the distal aorta after surgical repair of acute DeBakey type I aortic dissection: A review by Kirsch, Matthias, Legras, Antoine, Bruzzi, Matthieu, Louis, Nicolas

“…Summary Operated acute DeBakey type I aortic dissection has to be considered as a chronic aortic disease with the potential of late distal dilatation with…”
Get full text

A Case of Variant Scimitar Syndrome by Legras, Antoine, MD, Guinet, Claude, MD, Alifano, Marco, MD, PhD, FCCP, Lepilliez, Alain, MD, Régnard, Jean-François, MD

“…Scimitar syndrome is one of the large congenital pulmonary venolobar syndromes and is defined as hypogenetic lung associated with partial anomalous pulmonary…”
Get full text

Current Readings: The Most Influential and Recent Studies Regarding Resection of Lung Cancer in M1a Disease by Mordant, Pierre, MD, PhD, Rivera, Caroline, MD, Legras, Antoine, MD, Le Pimpec Barthes, Françoise, MD, PhD, Riquet, Marc, MD, PhD

“…M1A disease is a recent concept appearing in the 7th TNM classification of lung cancer. M1A encompasses two different entities, malignant pleural or…”
Get full text

Pneumothorax in Women of Child-Bearing Age by Legras, Antoine, MD, Mansuet-Lupo, Audrey, MD, Rousset-Jablonski, Christine, MD, Bobbio, Antonio, MD, Magdeleinat, Pierre, MD, Roche, Nicolas, MD, PhD, Regnard, Jean-François, MD, PhD, Gompel, Anne, MD, PhD, Damotte, Diane, MD, PhD, Alifano, Marco, MD, PhD, FCCP

“…Background A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiologic mechanisms continue to be debated, and…”
Get full text

EGFR -Mutant Non-Small-Cell Lung Cancer at Surgical Stages: What Is the Place for Tyrosine Kinase Inhibitors? by Cansouline, Xavier, Lipan, Béatrice, Sizaret, Damien, Tallet, Anne, Vandier, Christophe, Carmier, Delphine, Legras, Antoine

“…The ADAURA trial has been significant for the perception of tyrosine kinase inhibitors (TKIs) as a tool for early stage non-small-cell lung cancer (NSCLC). It…”
Get full text

A case report of cStage IIIB squamous cell lung carcinoma completely resected after downstaging with neoadjuvant therapy by Li, Jijia, Zu, Peng, Jakopović, Marko, Legras, Antoine, Saji, Hisashi, Onodera, Ken, Schlachtenberger, Georg, Liu, Hongxu

“…The most effective method and length of time for administering adjuvant immunotherapy after surgery for non-small cell lung cancer (NSCLC) are still unknown…”
Get full text

Kallikrein‐related peptidase 5 contributes to the remodeling and repair of bronchial epithelium by Lenga Ma Bonda, Woodys, Lavergne, Marion, Vasseur, Virginie, Brisson, Lucie, Roger, Sébastien, Legras, Antoine, Guillon, Antoine, Guyétant, Serge, Hiemstra, Pieter, Si-Tahar, Mustapha, Iochmann, Sophie, Reverdiau, Pascale

Get full text

Microscopic pN2 in lung cancer: a better prognosis? by Riquet, Marc, Legras, Antoine, Pricopi, Ciprian, Le-Pimpec-Barthes, Françoise

Get full text

Systemic Artery to Pulmonary Vein Fistula After Right Upper Lobectomy Demonstrated by 4-Dimensional Flow Magnetic Resonance Imaging by Legras, Antoine, Azarine, Arshid, Poitier, Bastien, Messas, Emmanuel, Le Pimpec-Barthes, Françoise

“…Postoperative systemic artery to pulmonary vein fistula is very rare. In this report, we describe an exceptional condition of both intrapulmonary arteriovenous…”
Get full text

Thoracic Endometriosis Syndrome Other Than Pneumothorax: Clinical and Pathological Findings by Bobbio, Antonio, Canny, Emeline, Mansuet Lupo, Audrey, Lococo, Filippo, Legras, Antoine, Magdeleinat, Pierre, Regnard, Jean-François, Gompel, Anne, Damotte, Diane, Alifano, Marco

“…Thoracic endometriosis syndrome refers to a broad spectrum of clinical manifestations related to the presence of ectopic intrathoracic endometrial tissue. Few…”
Get full text

Pneumothorax in women of child-bearing age: an update classification based on clinical and pathologic findings by Legras, Antoine, Mansuet-Lupo, Audrey, Rousset-Jablonski, Christine, Bobbio, Antonio, Magdeleinat, Pierre, Roche, Nicolas, Regnard, Jean-François, Gompel, Anne, Damotte, Diane, Alifano, Marco

“…A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiologic mechanisms continue to be debated, and pathologic aspects…”
Get full text