Search Results - "Legnani, F. G."

GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria by Simone, L., Capobianco, D. L., Di Palma, F., Binda, E., Legnani, F. G., Vescovi, A. L., Svelto, M., Pisani, F.

“…Tunneling nanotubes (TNTs) are long F-actin-positive plasma membrane bridges connecting distant cells, allowing the intercellular transfer of cellular cargoes,…”
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P12.08 HIGH GRADE GLIOMAS IN ELOQUENT AREAS: SURGICAL RESULTS AFTER TAILORED CRANIOTOMY WITH INTRA-OPERATIVE NEUROPHYSIOLOGICAL MONITORING (IOM) by Legnani, F. G., Cordella, R., Casali, C., Saladino, A., Mattei, L., Prada, F., Vetrano, I. G., Del Bene, M., Filippini, A., DiMeco, F.

“…BACKGROUND AND AIMS: Treatment of high grade gliomas is maximal safe resection followed by radiation and chemotherapy. When tumor is located in eloquent areas,…”
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Systemic administration of simvastatin after the onset of experimental subarachnoid hemorrhage attenuates cerebral vasospasm by MCGIRT, Matthew J, PRADILLA, Gustavo, MACDONALD, R. Loch, FINDLAY, J. Max, OGILVY, Christopher S, LEGNANI, Federico G, THAI, Quoc-Anh, RECINOS, Pablo F, TAMARGO, Rafael J, CLATTERBUCK, Richard E, DUMONT, Aaron S, HAMOF, Sagi, KASSELL, Neal F

“…Experimental evidence suggests that intercellular adhesion molecule-1 mediated leukocyte extravasation contributes to the pathogenesis of cerebral vasospasm…”
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Prevention of vasospasm by anti-CD11/CD18 monoclonal antibody therapy following subarachnoid hemorrhage in rabbits by PRADILLA, Gustavo, WANG, Paul P, LEGNANI, Federico G, OGATA, Lynn, DIETSCH, Gregory N, TAMARGO, Rafael J

“…Adhesion of leukocytes and their migration into the periadventitial space may be critical in the pathophysiology of vasospasm following subarachnoid hemorrhage…”
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Delayed intracranial delivery of a nitric oxide donor from a controlled-release polymer prevents experimental cerebral vasospasm in rabbits by Pradilla, Gustavo, Thai, Quoc-Anh, Legnani, Federico G, Hsu, Wesley, Kretzer, Ryan M, Wang, Paul P, Tamargo, Rafael J

“…Decreased local availability of nitric oxide (NO) may mediate chronic vasospasm after aneurysmal subarachnoid hemorrhage (SAH). Previous reports have shown…”
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Local delivery of ibuprofen via controlled-release polymers prevents angiographic vasospasm in a monkey model of subarachnoid hemorrhage by Pradilla, Gustavo, Thai, Quoc-Anh, Legnani, Federico G, Clatterbuck, Richard E, Gailloud, Philippe, Murphy, Kieran P, Tamargo, Rafael J

“…Adhesion and migration of leukocytes into the periadventitial space play a role in the pathophysiology of vasospasm after subarachnoid hemorrhage (SAH)…”
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Local delivery of a synthetic endostatin fragment for the treatment of experimental gliomas by Pradilla, Gustavo, Legnani, Federico G, Petrangolini, Giovanna, Francescato, Pierangelo, Chillemi, Francesco, Tyler, Betty M, Gaini, Sergio M, Brem, Henry, Olivi, Alessandro, DiMeco, Francesco

“…Endostatin is an anti-angiogenic agent that blocks matrix-metalloproteinase-2 and inhibits endothelial cell proliferation. Currently, endostatin is available…”
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Lysis of intracerebral hematoma with stereotactically implanted tissue plasminogen activator polymers in a rabbit model by THAI, Quoc-Anh, PRADILLA, Gustavo, LEGNANI, Federico G, KRETZER, Ryan M, HSU, Wesley, TAMARGO, Rafael J

“…Currently no adequate surgical treatment exists for spontaneous intracerebral hemorrhage (ICH). Implantable polymers can be used effectively to deliver…”
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Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours by Raza, Shaan M, Pradilla, Gustavo, Legnani, Federico G, Thai, Quoc Anh, Olivi, Alessandro, Weingart, Jon D, Brem, Henry

“…Recent advances in the treatment of malignant brain tumours have focused on the development of targeted local delivery of therapeutic agents, which combine…”
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Immunotherapy and biological modifiers for the treatment of malignant brain tumors by Marras, Carlo, Mendola, Carmela, Legnani, Federico Giuseppe, DiMeco, Francesco

“…The relative ineffectiveness of current therapies for malignant gliomas has led to the need for novel therapeutics. Therapies based on biologic modifiers are…”
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A novel rat model for the study of intraosseous metastatic spine cancer by MANTHA, Ajay, LEGNANI, Federico G, BAGLEY, Carlos A, GALLIA, Gary L, GARONZIK, Ira, PRADILLA, Gustavo, AMUNDSON, Eric, TYLER, Betty M, BREM, Henry, GOKASLAN, Ziya L

“…Although metastatic spinal disease constitutes a significant percentage of all spinal column tumors, an accessible and reproducible animal model has not been…”
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Pharmacokinetics of controlled-release polymers in the subarachnoid space after subarachnoid hemorrhage in rabbits by PRADILLA, Gustavo, WANG, Paul P, LEGNANI, Federico G, FRAZIER, James L, TAMARGO, Rafael J

“…Implantation of controlled-release polymers into the subarachnoid space to deliver drugs for treatment of vasospasm after subarachnoid hemorrhage (SAH) is…”
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A novel intramedullary spinal cord tumor model : functional, radiological, and histopathological characterization by MAVINKURVE, Gaurav, PRADILLA, Gustavo, LEGNANI, Federico G, TYLER, Betty M, BAGLEY, Carlos A, BREM, Henry, JALLO, George

“…Survival rates for high-grade intramedullary spinal cord tumors (IMSCTs) are approximately 30%, and optimal therapy has yet to be determined. Development of a…”
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