Search Results - "Legina, Maria S."
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Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action
Published in Inorganic chemistry (05-03-2018)“…Platinum-based anticancer coordination compounds are widely used in the treatment of many tumor types, where they are very effective but also cause severe side…”
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Biological evaluation of novel thiomaltol-based organometallic complexes as topoisomerase IIα inhibitors
Published in Journal of biological inorganic chemistry (01-05-2020)“…Topoisomerase IIα (topo2α) is an essential nuclear enzyme involved in DNA replication, transcription, recombination, chromosome condensation, and highly…”
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Thiomaltol-Based Organometallic Complexes with 1-Methylimidazole as Leaving Group: Synthesis, Stability, and Biological Behavior
Published in Chemistry : a European journal (21-11-2016)“…Thiomaltol, a potential S,O‐coordinating molecule, has been utilized for the complexation of four different organometallic fragments, yielding the desired…”
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Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations
Published in Journal of organometallic chemistry (01-02-2020)“…Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone…”
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