Search Results - "Legere, Stephanie"

Mast Cells in Cardiac Fibrosis: New Insights Suggest Opportunities for Intervention by Legere, Stephanie A, Haidl, Ian D, Légaré, Jean-François, Marshall, Jean S

“…Mast cells (MC) are innate immune cells present in virtually all body tissues with key roles in allergic disease and host defense. MCs recognize…”
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Increased mast cell density is associated with decreased fibrosis in human atrial tissue by Legere, Stephanie A., Haidl, Ian D., Castonguay, Mathieu C., Brunt, Keith R., Légaré, Jean-François, Marshall, Jean S.

“…Fibrotic remodelling of the atria is poorly understood and can be regulated by myocardial immune cell populations after injury. Mast cells are resident immune…”
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Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery by Aguiar, Christie M, Gawdat, Kareem, Legere, Stephanie, Marshall, Jean, Hassan, Ansar, Kienesberger, Petra C, Pulinilkunnil, Thomas, Castonguay, Mathieu, Brunt, Keith R, Legare, Jean-Francois

“…The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with…”
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Serum GDF15, a Promising Biomarker in Obese Patients Undergoing Heart Surgery by Sarkar, Shreya, Legere, Stephanie, Haidl, Ian, Marshall, Jean, MacLeod, Jeffrey B., Aguiar, Christie, Lutchmedial, Sohrab, Hassan, Ansar, Brunt, Keith R., Kienesberger, Petra, Pulinilkunnil, Thomas, Légaré, Jean-François

“…Background: Obesity is a risk factor that negatively impacts outcomes in patients undergoing heart surgery by mechanisms that are not well-defined nor…”
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Abstract QS38: Effect of Compound 21, a Selective Angiotensin II Type 2 Receptor Agonist, in an Abdominal Adhesion Murine Model by Boudreau, Colton, Jones, Courtney, Gareau, Alison, Levatte, Terry, Legere, Stephanie, Bezuhly, Michael

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The Selective Angiotensin II Type 2 Receptor Agonist Compound 21 Reduces Abdominal Adhesions in Mice by Boudreau, Colton, LeVatte, Terry, Jones, Courtney, Gareau, Alison, Legere, Stephanie, Bezuhly, Michael

“…Abdominal adhesions (AAs) are post-traumatic fibrous bands that connect visceral and/or peritoneal surfaces, leading to possible long-term complications. The…”
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A potential role for human mast cells in the resolution of cardiac inflammation by Legere, Stephanie, Haidl, Ian, Legare, Jean-Francois, Marshall, Jean

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Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery by Gawdat, Kareem, Legere, Stephanie, Wong, Chloe, Myers, Tanya, Marshall, Jean Sylvia, Hassan, Ansar, Brunt, Keith R, Kienesberger, Petra C, Pulinilkunnil, Thomas, Legare, Jean-Francois

“…The characteristics of circulating inflammatory cells (leukocytes) in patients undergoing heart surgery remains poorly understood. Recently,…”
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Abstract 16932: Local Production of Interleukin-33 and its Ability to Activate Mast Cells to Produce Pro-fibrotic Mediators May be Associated With Cardiac Fibrosis by Legere, Stephanie A, Marshall, Jean S, Légaré, Jean-François

“…IntroductionCardiac fibrosis is a complex process in which inflammation is a key component. Mast cells are innate immune sentinel cells found in multiple…”
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