Search Results - "Leger, Gerard"
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Quercetin, Siamois 1 and siamois 2 induce apoptosis in human breast cancer MDA-MB-435 cells xenograft in vivo
Published in Cancer biology & therapy (01-01-2007)“…We sought to investigate the apoptosis-inducing activities of quercetin, Siamois 1, and Siamois 2 against invasive estrogen-receptor negative MDA-MB 435 cells…”
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Capillary endothelial but not lymphatic function is restored under rosiglitazone in Zucker Diabetic Fatty rats
Published in Microvascular research (01-03-2009)“…If thiazolidinediones have shown beneficial effects on macrovascular endothelial function, their effects on microcirculation and lymphatic function are not…”
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A Simple and Efficient Procedure for the Synthesis of an Alendronate-Oligonucleotide Conjugate Via a Carbamate Linker
Published in Phosphorus, sulfur, and silicon and the related elements (01-01-1999)“…Alendronate. an munobisphosphonate used clinically for thc treatment of osteoporosis and others bones deseases is a synthetic analog of pyrophosphate in which…”
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Symmetrical and Unsymmetrical Bishophonate Esters Chemistry: Synthesis, Selective Hydrolysis, Isomerization
Published in Phosphorus, sulfur, and silicon and the related elements (01-01-1999)“…Over thc past few years, bisphosphonatcs have bcen receiving increased auention as a new class of pharmacologically active compound. As a continuation of our…”
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One Pot Synthesis of Bisphosphonate Esters: A Way to Synthesize Tetraphosphonate Esters
Published in Phosphorus, sulfur, and silicon and the related elements (01-01-1999)“…Several methods for the preparation of symmetrical bisphosphonates of general type (RO) 2 P(O)(R′OH)P(O)(OR) 2 , have been developed, and investigated for…”
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In vitro and in vivo study of 99mTc-MIBI encapsulated in PEG-liposomes: a promising radiotracer for tumour imaging
Published in European journal of nuclear medicine and molecular imaging (01-04-2003)“…Encapsulation of technetium-99m sestamibi ((99m)Tc-MIBI) in polyethyleneglycol-liposomes ((99m)Tc-MIBI-PEG-liposomes) could extend the duration of its…”
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In vitro evaluation and biodistribution of a 99mTc-labeled anti-VEGF peptide targeting neuropilin-1
Published in Nuclear medicine and biology (01-07-2004)“…Neuropilins (NRP) are receptors of angiogenic vascular endothelial growth factor (VEGF). Their overexpression was correlated with tumor angiogenesis and growth…”
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A Continuous Transition from A-DNA to B-DNA in the 1:1 Complex between Nogalamycin and the Hexamer dCCCGGG
Published in The Journal of biological chemistry (28-06-1996)“…The antibiotic nogalamycin, a drug with high specificity for TG and CG steps in double-stranded DNA, has been crystallized as a 1:1 complex with the hexamer…”
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Sleep apnea syndrome: late sequela of poliomyelitis
Published in Revue des maladies respiratoires (1988)“…A syndrome of sleep apnoea may appear 15 to 29 years after acute anterior poliomyelitis (PAA). It is generally a mixed syndrome with an association of central…”
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