Search Results - "Legault, L."
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Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryo
Published in Epigenetics (02-08-2020)“…In early embryos, DNA methylation is remodelled to initiate the developmental program but for mostly unknown reasons, methylation marks are acquired unequally…”
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Predictors of cardiovascular risk among patients with type 1 diabetes: A critical analysis of the metabolic syndrome and its components
Published in Diabetes & metabolism (01-06-2017)“…Abstract Patients with type 1 diabetes (T1D) are at increased risk for cardiovascular diseases. The metabolic syndrome (MetS), a complex disorder defined by a…”
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A global experiment on motivating social distancing during the COVID-19 pandemic
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2022)“…SignificanceCommunicating in ways that motivate engagement in social distancing remains a critical global public health priority during the COVID-19 pandemic…”
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Efficacy of dual-hormone artificial pancreas to alleviate the carbohydrate-counting burden of type 1 diabetes: A randomized crossover trial
Published in Diabetes & metabolism (01-02-2016)“…Abstract Aim Carbohydrate-counting is a complex task for many patients with type 1 diabetes. This study examined whether an artificial pancreas, delivering…”
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Adopting and expanding ethical principles for generative artificial intelligence from military to healthcare
Published in NPJ digital medicine (02-12-2023)“…In 2020, the U.S. Department of Defense officially disclosed a set of ethical principles to guide the use of Artificial Intelligence (AI) technologies on…”
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Pre-implantation alcohol exposure induces lasting sex-specific DNA methylation programming errors in the developing forebrain
Published in Clinical epigenetics (01-12-2021)“…Prenatal alcohol exposure is recognized for altering DNA methylation profiles of brain cells during development, and to be part of the molecular basis…”
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Association of aerobic fitness level with exercise-induced hypoglycaemia in Type 1 diabetes
Published in Diabetic medicine (01-12-2016)“…Aim To determine the impact of physical fitness level on hypoglycaemia risk during exercise in people with Type 1 diabetes. Methods A total of 44 patients [34…”
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Prevalence of Myopia in Newly Enlisted Airmen at Joint Base San Antonio
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2020)“…Myopia is the most common type of refractive error and can lead to significant visual impairment. The frequency of myopia has risen considerably, and its…”
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KFC Server: interactive forecasting of protein interaction hot spots
Published in Nucleic acids research (01-07-2008)“…The KFC Server is a web-based implementation of the KFC (Knowledge-based FADE and Contacts) model—a machine learning approach for the prediction of binding hot…”
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Timing of insulin basal rate reduction to reduce hypoglycemia during late post-prandial exercise in adults with type 1 diabetes using insulin pump therapy: A randomized crossover trial
Published in Diabetes & metabolism (01-06-2019)“…To compare the efficacy of three timings to decrease basal insulin infusion rate to reduce exercise-induced hypoglycaemia in patients with type 1 diabetes…”
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Outcomes in children of women with type 2 diabetes exposed to metformin versus placebo during pregnancy (MiTy Kids): a 24-month follow-up of the MiTy randomised controlled trial
Published in The lancet. Diabetes & endocrinology (01-03-2023)“…Metformin is increasingly being used during pregnancy, with potentially adverse long-term effects on children. We aimed to examine adiposity in children of…”
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Multidrug-Resistant Organisms from Ophthalmic Cultures: Antibiotic Resistance and Visual Acuity
Published in Military medicine (14-08-2020)“…Abstract Introduction There is a growing trend of multidrug-resistant organisms (MDRO). The goal of this study was to characterize MDRO at a single center from…”
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Job Satisfaction, Well-Being, and Burnout among Ophthalmology Educators
Published in Journal of academic ophthalmology (2017) (01-01-2023)“…This article assesses the prevalence of burnout among ophthalmology educators and identifies opportunities to improve well-being in this population. The…”
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Applying a Military Teleophthalmology Mobile App in a Noncombat Emergent Care Setting
Published in Military medicine (29-08-2023)“…ABSTRACT Introduction Teleophthalmology has a natural role in the military due to the inherent organization of its medical system, which provides care to…”
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Teleophthalmology in the United States Army: A Review From 2004 Through 2018
Published in Military medicine (04-01-2023)“…ABSTRACT Introduction We describe results of the U.S. Army Ocular Teleconsultation program from 2004 through 2018 as well as the current condition, benefits,…”
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Perspectives of Resident and Attending Ophthalmologists on Common Ethical Dilemmas in Research
Published in Journal of academic ophthalmology (2017) (01-07-2023)“…To assess how resident and attending ophthalmologists perceive and evaluate ethically controversial scenarios regarding mentorship, authorship, and ethics…”
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Impact of elective hospital admissions on glycaemic control in adolescents with poorly controlled type 1 diabetes
Published in Diabetes & metabolism (01-12-2013)“…Abstract Aim Different treatment strategies have been used to manage adolescents with poorly controlled type 1 diabetes. We investigated whether a brief…”
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Post-breakfast closed-loop glucose control is improved when accompanied with carbohydrate-matching bolus compared to weight-dependent bolus
Published in Diabetes & metabolism (01-06-2014)“…Abstract Aim We compared post-breakfast closed-loop glucose control either matched with a carbohydrate-matching bolus or a weight-dependent bolus. Methods…”
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Why do families enrol in paediatric weight management? A parental perspective of reasons and facilitators
Published in Child : care, health & development (01-03-2016)“…Background Few children with obesity who are referred for weight management end up enroled in treatment. Factors enabling enrolment are poorly understood. Our…”
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