Search Results - "Lefur, G"

Formulation of the measurement problem and application to antenna measurement correction by Quennelle, A., Chabory, A., Contreres, R., LeFur, G., Pouliguen, P.

“…After designing and prototyping phases, the antenna measurement process is run in order to assess and optimize the antenna performances. However the…”
Get full text

Molecular cloning of a human β3-adrenergic receptor cDNA by Lelias, J.M., Kaghad, M., Rodriguez, M., Chalon, P., Bonnin, J., Dupre, I., Delpech, B., Bensaid, M., LeFur, G., Ferrara, P., Caput, D.

“…We report the molecular cloning of a β3-adrenergic receptor β3-AR cDNA from human brown adipose tissue. The cDNA-encoded protein is identical to the previously…”
Get full text

Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor by Emonds-Alt, X, Golliot, F, Pointeau, P, Le Fur, G, Breliere, J C

“…[3H]SR 48968, a radiolabeled nonpeptide antagonist of NK-2 receptor, has been tested in ligand-receptor binding assays using rat duodenum, hamster urinary…”
Get more information

Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors by ARNONE, M, MARUANI, J, CHAPERON, F, THIEBOT, M.-H, PONCELET, M, SOUBRIE, P, LE FUR, G

“…SR 141716, a selective central CB1 cannabinoid receptor antagonist, markedly and selectively reduces sucrose feeding and drinking as well as neuropeptide…”
Get full text

A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1. Evidence for a new model of receptor/ligand interactions by Bouaboula, M, Perrachon, S, Milligan, L, Canat, X, Rinaldi-Carmona, M, Portier, M, Barth, F, Calandra, B, Pecceu, F, Lupker, J, Maffrand, J P, Le Fur, G, Casellas, P

“…In the present study, we showed that Chinese hamster ovary (CHO) cells transfected with human central cannabinoid receptor (CB1) exhibit high constitutive…”
Get full text

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor by Rinaldi-Carmona, Murielle, Barth, Francis, Héaulme, Michel, Shire, David, Calandra, Bernard, Congy, Christian, Martinez, Serge, Maruani, Jeanne, Néliat, Gervais, Caput, Daniel, Ferrara, Pascual, Soubrié, Philippe, Brelière, Jean Claude, Le Fur, Gérard

“…SR141716A is the first selective and orally active antagonist of the brain cannabinoid receptor. This compound displays nanomolar affinity for the central…”
Get full text

Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1 by Bouaboula, M, Poinot-Chazel, C, Bourrié, B, Canat, X, Calandra, B, Rinaldi-Carmona, M, Le Fur, G, Casellas, P

“…The G-protein-coupled central cannabinoid receptor (CB1) has been shown to be functionally associated with several biological responses including inhibition of…”
Get full text

Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716 by TERRANOVA, J.-P, STORME, J.-J, LAFON, N, PERIO, A, RINALDI-CARMONA, M, LE FUR, G, SOUBRIE, P

“…Social short-term memory in rodents is based on the recognition of a juvenile by an adult conspecific when the juvenile is presented on two successive…”
Get full text

Molecular cloning of a levocabastine-sensitive neurotensin binding site by Chalon, Pascale, Vita, Natalio, Kaghad, Mourad, Guillemot, Marie, Bonnin, Jacques, Delpech, Bruno, Le Fur, Gerard, Ferrara, Pascual, Caput, Daniel

“…A search for sequences homologous to the neurotensin receptor cDNA in a rat hypothalamic library has identified a novel neurotensin receptor (NTR-2). The 1539…”
Get full text

An Amino-terminal Variant of the Central Cannabinoid Receptor Resulting from Alternative Splicing by Shire, D, Carillon, C, Kaghad, M, Calandra, B, Rinaldi-Carmona, M, Le Fur, G, Caput, D, Ferrara, P

“…The cDNA sequences encoding the central cannabinoid receptor, CB1, are known for two species, rat and human. However, little information concerning the…”
Get full text

A 3D model of the peripheral benzodiazepine receptor and its implication in intra mitochondrial cholesterol transport by Bernassau, J M, Reversat, J L, Ferrara, P, Caput, D, Lefur, G

“…A three-dimensional (3D) model of the peripheral benzodiazepine receptor (PBR) has been built using molecular dynamics simulations. The transmembrane domain of…”
Get more information

Biochemical and pharmacological characterisation of SR141716A, the first potent and selective brain cannabinoid receptor antagonist by Rinaldi-Carmona, M, Barth, F, Héaulme, M, Alonso, R, Shire, D, Congy, C, Soubrié, P, Brelière, J C, Le Fur, G

“…SR141716A is a selective, potent and orally active antagonist of the brain cannabinoid receptor with a long duration of action. This compound shows high…”
Get more information

Involvement of Peripheral Benzodiazepine Receptors in the Protection of Hematopoietic Cells Against Oxygen Radical Damage by Carayon, P., Portier, M., Dussossoy, D., Bord, A., Petitprêtre, G., Canat, X., Fur, G.Le, Casellas, P.

“…Several putative functions have been attributed to the peripheral benzodiazepine receptor (PBR), but its precise physiologic role has not been elucidated. In…”
Get full text

Cannabinoids enhance human B-cell growth at low nanomolar concentrations by Derocq, J.-M., Ségui, M., Marchand, J., Le Fur, G., Casellas, P.

“…This study examined the effect of cannabinoid ligands on human tonsillar B-cells activated either through cross-linking of surface immunoglobulins or ligation…”
Get full text

Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist by Gully, D, Labeeuw, B, Boigegrain, R, Oury-Donat, F, Bachy, A, Poncelet, M, Steinberg, R, Suaud-Chagny, M F, Santucci, V, Vita, N, Pecceu, F, Labbé-Jullié, C, Kitabgi, P, Soubrié, P, Le Fur, G, Maffrand, J P

“…SR 142948A, 2-[[5-(2,6-dimethoxyphenyl)-1-(4-(N-(3-dimethylaminopropyl)-N-methylc arbamoyl)-2-isopropylphenyl)-1H-pyrazole3-carbonyl]amino]…”
Get more information

Biochemical and Pharmacological Profile of a Potent and Selective Nonpeptide Antagonist of the Neurotensin Receptor by Gully, Danielle, Canton, Maryse, Boigegrain, Robert, Jeanjean, Francis, Molimard, Jean-Charles, Poncelet, Martine, Gueudet, Christiane, Heaulme, Michel, Leyris, Roger, Brouard, Aline, Pelaprat, Didier, Labbe-Jullie, Catherine, Mazella, Jean, Soubrie, Philippe, Maffrand, Jean-Pierre, Rostene, William, Kitabgi, Patrick, Le Fur, Gerard

“…We describe the characteristics of SR 48692, a selective, nonpeptide antagonist of the neurotensin receptor. In vitro, this compound competitively…”
Get full text

Stimulation of Cannabinoid Receptor CB1 Induces krox-24 Expression in Human Astrocytoma Cells by Bouaboula, Monsif, Bourrié, Bernard, Rinaldi-Carmona, Murielle, Shire, David, Fur, Gérard Le, Casellas, Pierre

“…The recent isolation and cloning of the G protein-coupled central cannabinoid receptor (CB1) from brain tissue has provided a molecular basis to elucidate how…”
Get full text

Expression of Central and Peripheral Cannabinoid Receptors in Human Immune Tissues and Leukocyte Subpopulations by Galiègue, Sylvaine, Mary, Sophie, Marchand, Jean, Dussossoy, Danielle, Carrière, Dominique, Carayon, Pierre, Bouaboula, Monsif, Shire, David, Fur, Gérard, Casellas, Pierre

“…Two proteins with seven transmembrane‐spanning domains typical of guanosine‐nucleotide‐binding‐protein‐coupled receptors have been identified as cannabinoid…”
Get full text

Characterization and localization of leptin receptors in the rat kidney by Serradeil-Le Gal, Claudine, Raufaste, Danièle, Brossard, Gabrielle, Pouzet, Brigitte, Marty, Eléonore, Maffrand, Jean-Pierre, Le Fur, Gérard

“…Characterization and localization of leptin binding sites were investigated in rat kidneys using [ 125I]leptin as a ligand. [ 125I]Leptin specific binding was…”
Get full text

Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors by SERRADEIL-LE GAL, C, WAGNON, J, GUILLON, G, CANTAU, B, BARBERIS, C, TRUEBA, M, ALA, Y, JARD, S, GARCIA, C, LACOUR, C, GUIRAUDOU, P, CHRISTOPHE, P, VILLANOVA, G, NISATO, D, MAFFRAND, J. P, LE FUR, G

“…SR 49059, a new potent and selective orally active, nonpeptide vasopressin (AVP) antagonist has been characterized in several in vitro and in vivo models. SR…”
Get full text