Search Results - "Lefranc, Amandine"
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Enantioselective formal total synthesis of the Dendrobatidae frog toxin, (+)-pumiliotoxin B, via O-directed alkyne free radical hydrostannation
Published in Tetrahedron letters (27-04-2011)“…Herein we describe our application of the O-directed free radical hydrostannation of disubstituted alkylacetylenes (with Ph 3SnH and Et 3B) to the…”
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Journal Article -
2
Synthesis of A83586C Analogs with Potent Anticancer and β-Catenin/ TCF4/Osteopontin Inhibitory Effects and Insights Into How A83586C Modulates E2Fs and pRb
Published in Organic letters (05-02-2009)“…The synthesis of three potent new antitumor agents is described: the A83586C−citropeptin hybrid (1), the A83586C−GE3 hybrid (2), and l-Pro-A83586C (3)…”
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Journal Article -
3
Preparation of enantiomerically pure ( E)-β-sulfinylenones from β-ketoesters
Published in Tetrahedron letters (29-08-2005)“…Enantiomerically pure ( E)-β-sulfinylenones are smoothly prepared from β-ketoesters in three steps with good overall yield. Since they can be the substrates of…”
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Journal Article -
4
Synthetic studies on molecules related to the azinothricin family and allopumiliotoxin 339a
Published 01-01-2008“…The Azinothricin family of compounds are based on a cyclodepsipeptide core and were first encountered in the late 1980s. Most of the members exhibit potent…”
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Dissertation -
5
Synthetic studies on molecules related to the azinothricin family and allopumiliotoxin 339A
Published 01-01-2008“…The Azinothricin family of compounds are based on a cyclodepsipeptide core and were first encountered in the late 1980s. Most of the members exhibit potent…”
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Dissertation