Search Results - "Leffler, Daniel A"

Celiac disease: a comprehensive current review by Caio, Giacomo, Volta, Umberto, Sapone, Anna, Leffler, Daniel A, De Giorgio, Roberto, Catassi, Carlo, Fasano, Alessio

“…Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible…”
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Larazotide Acetate for Persistent Symptoms of Celiac Disease Despite a Gluten-Free Diet: A Randomized Controlled Trial by Leffler, Daniel A, Kelly, Ciaran P, Green, Peter H.R, Fedorak, Richard N, DiMarino, Anthony, Perrow, Wendy, Rasmussen, Henrik, Wang, Chao, Bercik, Premysl, Bachir, Natalie M, Murray, Joseph A

“…Background & Aims Celiac disease (CeD) is a prevalent autoimmune condition. Recurrent signs and symptoms are common despite treatment with a gluten-free diet…”
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Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 by Junker, Yvonne, Zeissig, Sebastian, Kim, Seong-Jun, Barisani, Donatella, Wieser, Herbert, Leffler, Daniel A, Zevallos, Victor, Libermann, Towia A, Dillon, Simon, Freitag, Tobias L, Kelly, Ciaran P, Schuppan, Detlef

“…Ingestion of wheat, barley, or rye triggers small intestinal inflammation in patients with celiac disease. Specifically, the storage proteins of these cereals…”
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The Oslo definitions for coeliac disease and related terms by Ludvigsson, Jonas F, Leffler, Daniel A, Bai, Julio C, Biagi, Federico, Fasano, Alessio, Green, Peter H R, Hadjivassiliou, Marios, Kaukinen, Katri, Kelly, Ciaran P, Leonard, Jonathan N, Lundin, Knut Erik Aslaksen, Murray, Joseph A, Sanders, David S, Walker, Marjorie M, Zingone, Fabiana, Ciacci, Carolina

“…The literature suggests a lack of consensus on the use of terms related to coeliac disease (CD) and gluten. A multidisciplinary task force of 16 physicians…”
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Short and long-term follow-up and clinical outcomes in patients with celiac disease in a large private practice setting by Khurana, Akash, Leffler, Daniel A, Gomez, Kayeromi, Thukral, Chandrashekhar

“…Celiac disease (CD) is caused by an immune response to gluten and treatment is adherence to a gluten-free diet. Guidelines from studies in large academic…”
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Association Between Inflammatory Bowel Diseases and Celiac Disease: A Systematic Review and Meta-Analysis by Pinto-Sanchez, Maria Ines, Seiler, Caroline L., Santesso, Nancy, Alaedini, Armin, Semrad, Carol, Lee, Anne R., Bercik, Premysl, Lebwohl, Benjamin, Leffler, Daniel A., Kelly, Ciaran P., Moayyedi, Paul, Green, Peter H., Verdu, Elena F.

“…There is controversy over the association between celiac disease (CeD) and inflammatory bowel diseases (IBD). We performed a systematic review and…”
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Development and validation of a biomarker for diarrhea-predominant irritable bowel syndrome in human subjects by Pimentel, Mark, Morales, Walter, Rezaie, Ali, Marsh, Emily, Lembo, Anthony, Mirocha, James, Leffler, Daniel A, Marsh, Zachary, Weitsman, Stacy, Chua, Kathleen S, Barlow, Gillian M, Bortey, Enoch, Forbes, William, Yu, Allen, Chang, Christopher

“…Diarrhea-predominant irritable bowel syndrome (IBS) is diagnosed through clinical criteria after excluding "organic" conditions, and can be precipitated by…”
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Treatment of Clostridium difficile -Associated Disease by Leffler, Daniel A, Lamont, J. Thomas

“…Clostridium difficile infection is an increasing burden to the health care system, totaling more than $1 billion/year in the United States. Treatment of…”
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Neurological Manifestations of Neuropathy and Ataxia in Celiac Disease: A Systematic Review by Mearns, Elizabeth S, Taylor, Aliki, Thomas Craig, Kelly J, Puglielli, Stefanie, Leffler, Daniel A, Sanders, David S, Lebwohl, Benjamin, Hadjivassiliou, Marios

“…Celiac disease (CD) is an immune-mediated gastrointestinal disorder driven by innate and adaptive immune responses to gluten. Patients with CD are at an…”
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Diagnosis and Updates in Celiac Disease by Shannahan, Sarah, MD, Leffler, Daniel A., MD, MS

“…Celiac disease is an autoimmune disorder induced by gluten in genetically susceptible individuals. It can result in intraintestinal and extraintestinal…”
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Immunoglobulin A deficiency in celiac disease in the United States by Pallav, Kumar, Xu, Hua, Leffler, Daniel A., Kabbani, Toufic, Kelly, Ciaran P.

“…Background and Aims: Multiple European studies report increased prevalence of selective immunoglobulin A deficiency (SIgAD) and partial immunoglobulin A…”
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The Evolving Landscape of Biomarkers in Celiac Disease: Leading the Way to Clinical Development by Smithson, Glennda, Siegelman, Jenifer, Oki, Toshihiko, Maxwell, Joseph R, Leffler, Daniel A

“…Celiac disease is a common immune-mediated disease characterized by abnormal T-cell responses to gluten. For many patients, symptoms and intestinal damage can…”
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Is Autoimmunity Infectious? The Effect of Gastrointestinal Viral Infections and Vaccination on Risk of Celiac Disease Autoimmunity by Silvester, Jocelyn A., MD, PhD, Leffler, Daniel A., MD, MSc

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Acid suppression therapy does not predispose to Clostridium difficile infection: the case of the potential bias by Novack, Lena, Kogan, Slava, Gimpelevich, Larisa, Howell, Michael, Borer, Abraham, Kelly, Ciarán P, Leffler, Daniel A, Novack, Victor

“…An adverse effect of acid-suppression medications on the occurrence of Clostridium difficile infection (CDI) has been a common finding of many, but not all…”
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Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool by Song, Linan, Zhao, Mingwei, Duffy, David C, Hansen, Joshua, Shields, Kelsey, Wungjiranirun, Manida, Chen, Xinhua, Xu, Hua, Leffler, Daniel A, Sambol, Susan P, Gerding, Dale N, Kelly, Ciarán P, Pollock, Nira R

“…The currently available diagnostics for Clostridium difficile infection (CDI) have major limitations. Despite mounting evidence that toxin detection is…”
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Public reporting of colonoscopy quality is associated with an increase in endoscopist adenoma detection rate by Abdul-Baki, Heitham, MD, Schoen, Robert E., MD, MPH, Dean, Katie, Rose, Sherri, PhD, Leffler, Daniel A., MD, Kuganeswaran, Eliathamby, MD, Morris, Michele, Carrell, David, PhD, Mehrotra, Ateev, MD

“…Background Colonoscopy is the predominant method for colorectal cancer screening in the United States. Previous studies have documented variation across…”
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Exploring the Strange New World of Non-Celiac Gluten Sensitivity by Lebwohl, Benjamin, MD, Leffler, Daniel A., MD, MS

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Angiotensin II receptor blockers and gastrointestinal adverse events of resembling sprue-like enteropathy: a systematic review by Kamal, Ayesha, Fain, Christopher, Park, Angela, Wang, Peiqi, Gonzalez-Velez, Eduardo, Leffler, Daniel A, Hutfless, Susan M

“…Olmesartan, an angiotensin II receptor blocker (ARB), is associated with gastrointestinal symptoms resembling sprue-like enteropathy. Some have proposed that…”
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A Multi-Center Prospective Derivation and Validation of a Clinical Prediction Tool for Severe Clostridium difficile Infection by Na, Xi, Martin, Alan J, Sethi, Saurabh, Kyne, Lorraine, Garey, Kevin W, Flores, Sarah W, Hu, Mary, Shah, Dhara N, Shields, Kelsey, Leffler, Daniel A, Kelly, Ciarán P

“…Prediction of severe clinical outcomes in Clostridium difficile infection (CDI) is important to inform management decisions for optimum patient care…”
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Clostridium difficile Infection by Leffler, Daniel A, Lamont, J. Thomas

“…This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this nosocomial and potentially fatal infectious diarrhea, as well as the…”
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