Search Results - "Lefevre, Arthur"
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Oxytocin Signaling in the Central Amygdala Modulates Emotion Discrimination in Mice
Published in Current biology (17-06-2019)“…Recognition of other’s emotions influences the way social animals interact and adapt to the environment. The neuropeptide oxytocin (OXT) has been implicated in…”
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A comparison of methods to measure central and peripheral oxytocin concentrations in human and non-human primates
Published in Scientific reports (08-12-2017)“…Oxytocin (OT) concentration in the blood is considered to be a marker of its action in the brain. However, two problems have emerged when measuring OT level in…”
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A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System
Published in Neuron (Cambridge, Mass.) (03-07-2019)“…Oxytocin (OT) release by axonal terminals onto the central nucleus of the amygdala exerts anxiolysis. To investigate which subpopulation of OT neurons…”
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Oxytocin and Serotonin Brain Mechanisms in the Nonhuman Primate
Published in The Journal of neuroscience (12-07-2017)“…Oxytocin (OT) is increasingly studied for its therapeutic potential in psychiatric disorders, which are associated with the deregulation of several…”
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Oxytocinergic Feedback Circuitries: An Anatomical Basis for Neuromodulation of Social Behaviors
Published in Frontiers in neural circuits (14-06-2021)“…Oxytocin (OT) is a neuropeptide produced by hypothalamic neurons and is known to modulate social behavior among other functions. Several experiments have shown…”
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An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
Published in Nature communications (24-02-2023)“…The hypothalamic neuropeptide oxytocin (OT) exerts prominent analgesic effects via central and peripheral action. However, the precise analgesic pathways…”
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Oxytocin Fails to Recruit Serotonergic Neurotransmission in the Autistic Brain
Published in Cerebral cortex (New York, N.Y. 1991) (01-12-2018)“…Abstract Oxytocin (OT), a neuropeptide involved in affiliation has been shown to enhance social skills in patients with autism spectrum disorders (ASD)…”
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Efficiency of cell-type specific and generic promoters in transducing oxytocin neurons and monitoring their neural activity during lactation
Published in Scientific reports (18-11-2021)“…Hypothalamic oxytocin (OXT) and arginine-vasopressin (AVP) neurons have been at the center of several physiological and behavioral studies. Advances in viral…”
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Viral vectors for opto-electrode recording and photometry-based imaging of oxytocin neurons in anesthetized and socially interacting rats
Published in STAR protocols (18-03-2022)“…Here, we present a step-by-step protocol to target, record, and manipulate the activity of oxytocin neurons in awake rats. The protocol includes a procedure to…”
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Increased gingival crevicular fluid levels of soluble triggering receptor expressed on myeloid cells (sTREM) -1 in severe periodontitis
Published in Journal of clinical periodontology (01-12-2012)“…Aim This study was designed to evaluate the presence of a new regulator of innate immunity in periodontitis: the soluble form of triggering receptor on myeloid…”
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The two fold role of oxytocin in social developmental disorders: A cause and a remedy?
Published in Neuroscience and biobehavioral reviews (01-04-2016)“…Oxytocin is widely used by obstetricians to induce or facilitate labor. The long lasting consequences of oxytocin administration remain however unknown. Here,…”
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Long‐range projections of oxytocin neurons in the marmoset brain
Published in Journal of neuroendocrinology (01-06-2024)“…The neurohormone oxytocin (OT) has become a major target for the development of novel therapeutic strategies to treat psychiatric disorders such as autism…”
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13
Restoring consciousness with vagus nerve stimulation
Published in Current biology (25-09-2017)“…Patients lying in a vegetative state present severe impairments of consciousness [1] caused by lesions in the cortex, the brainstem, the thalamus and the white…”
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Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons
Published in Nature neuroscience (01-09-2020)“…Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant brain regions have been extensively studied, OT neuron…”
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Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats
Published in Molecular psychiatry (01-02-2024)“…Oxytocin plays an important role in modulating social recognition memory. However, the direct implication of oxytocin neurons of the paraventricular nucleus of…”
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Oxytocin promotes prefrontal population activity via the PVN-PFC pathway to regulate pain
Published in Neuron (Cambridge, Mass.) (07-06-2023)“…Neurons in the prefrontal cortex (PFC) can provide top-down regulation of sensory-affective experiences such as pain. Bottom-up modulation of sensory coding in…”
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Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents
Published in Nature neuroscience (01-04-2021)“…Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural circuits. In the central amygdala, the release of OT modulates…”
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Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
Published in Nature nanotechnology (01-10-2023)“…Crossing the blood–brain barrier in primates is a major obstacle for gene delivery to the brain. Adeno-associated viruses (AAVs) promise robust, non-invasive…”
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Imaging neuropeptide effects on human brain function
Published in Cell and tissue research (01-01-2019)“…The discovery of prosocial effects of oxytocin (OT) opened new directions for studying neuropeptide effects on the human brain. However, despite obvious…”
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An Association Between Serotonin 1A Receptor, Gray Matter Volume, and Sociability in Healthy Subjects and in Autism Spectrum Disorder
Published in Autism research (01-11-2020)“…Central serotonin is an important molecular pathway, involved in the regulation of social behavior and gray matter volume (GMV). In men with autism spectrum…”
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