Search Results - "Lefebvre, Charles"

Implementation of a fast relative digital temperature sensor to achieve thermal protection in Zynq SoC technology by Lefebvre, Charles-Alexis, Montero, Jose Luis, Rubio, Leire

“…More and more industrial embedded systems are developed to undergo hard environmental conditions, especially high temperatures. To prevent this impact,…”
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Inhibitor of Apoptosis Protein cIAP2 Is Essential for Lipopolysaccharide-Induced Macrophage Survival by Conte, Damiano, Holcik, Martin, Lefebvre, Charles A., LaCasse, Eric, Picketts, David J., Wright, Kathryn E., Korneluk, Robert G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death by Mahoney, Douglas J., Lefebvre, Charles, Allan, Kristina, Brun, Jan, Sanaei, Cina A., Baird, Stephen, Pearce, Nelson, Grönberg, Susanna, Wilson, Brian, Prakesh, Mikael, Aman, Ahmed, Isaac, Methvin, Mamai, Ahmed, Uehling, David, Al-Awar, Rima, Falls, Theresa, Alain, Tommy, Stojdl, David F.

“…To identify therapeutic opportunities for oncolytic viral therapy, we conducted genome-wide RNAi screens to search for host factors that modulate rhabdoviral…”
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Transforming the prostatic tumor microenvironment with oncolytic virotherapy by Atherton, Matthew J., Stephenson, Kyle B., Tzelepis, Fanny, Bakhshinyan, David, Nikota, Jake K., Son, Hwan Hee, Jirovec, Anna, Lefebvre, Charles, Dvorkin-Gheva, Anna, Ashkar, Ali A., Wan, Yonghong, Stojdl, David F., Belanger, Eric C., Breau, Rodney H., Bell, John C., Saad, Fred, Singh, Sheila K., Diallo, Jean-Simone, Lichty, Brian D.

“…Prostate cancer (PCa) was estimated to have the second highest global incidence rate for male non-skin tumors and is the fifth most deadly in men thus…”
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The SELENE Deep Learning Acceleration Framework for Safety-related Applications by Medina, Laura, Carrion, Salvador, Andreu, Pablo, Picornell, Tomas, Flich, Jose, Hernandez, Carles, Sandoval, Michael, Sainz, Markel, Lefebvre, Charles-Alexis, Ronnback, Martin, Matschnig, Martin, Wess, Matthias, Taucher, Herbert

“…The goal of the H2020 SELENE project is the development of a flexible computing platform for autonomous applications that includes built-in hardware support…”
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Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity by Walsh, Scott R., Bastin, Donald, Chen, Lan, Nguyen, Andrew, Storbeck, Christopher J., Lefebvre, Charles, Stojdl, David, Bramson, Jonathan L., Bell, John C., Wan, Yonghong

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Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics by MCMANUS, Dan C, LEFEBVRE, Charles A, CHERTON-HORVAT, Gabriele, ST-JEAN, Martine, KANDIMALLA, Ekambar R, AGRAWAL, Sudhir, MORRIS, Stephen J, DURKIN, Jon P, LACASSE, Eric C

“…Stable expression of short-hairpin RNAs (shRNAs) directed against the X-linked inhibitor of apoptosis (XIAP) resulted in the generation of three MDA-MB-231…”
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Genome-wide RNAi Screening to Identify Host Factors That Modulate Oncolytic Virus Therapy by Allan, Kristina J, Mahoney, Douglas J, Baird, Stephen D, Lefebvre, Charles A, Stojdl, David F

“…High-throughput genome-wide RNAi (RNA interference) screening technology has been widely used for discovering host factors that impact virus replication. Here…”
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A new internal-ribosome-entry-site motif potentiates XIAP- mediated cytoprotection by Korneluk, Robert G, Holcik, Martin, Lefebvre, Charles, Yeh, Chiaoli, Chow, Terry

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Spurious splicing within the XIAP 5′ UTR occurs in the Rluc/Fluc but not the βgal/CAT bicistronic reporter system by HOLCIK, MARTIN, GRABER, TYSON, LEWIS, STEPHEN M., LEFEBVRE, CHARLES A., LACASSE, ERIC, BAIRD, STEPHEN

“…X-chromosome-linked inhibitor of apoptosis, XIAP, has been shown to contain a strong internal ribosome entry site (IRES) within its 5′ untranslated region…”
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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes by Listen, Peter, Roy, Natalie, Tamai, Katsuyuki, Lefebvre, Charles, Baird, Stephen, Cherton-Horvat, Gabriele, Farahani, Reza, McLean, Michael, lkeda, Joh-E, Mackenzie, Alex, Korneluk, Robert G

“…Dysregulation of apoptosis can result in inappropriate suppression of cell death, as occurs in the development of some cancers, or in failure to control the…”
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Activating Peripheral Innate Immunity Enables Safe and Effective Oncolytic Virotherapy in the Brain by Balathasan, Lukxmi, Tang, Vera A., Yadollahi, Beta, Brun, Jan, Labelle, Melanie, Lefebvre, Charles, Swift, Stephanie L., Stojdl, David F.

“…The oncolytic mutant vesicular stomatitis virus VSVΔ51 achieves robust efficacy in multiple extracranial tumor models. Yet for malignancies of the brain,…”
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Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes by Holcik, Martin, Lefebvre, Charles A, Hicks, Keiko, Korneluk, Robert G

“…Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of Apoptosis…”
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The Hippocampal Neurons of Neuronal Apoptosis Inhibitory Protein 1 (NAIP1)-Deleted Mice Display Increased Vulnerability to Kainic Acid-Induced Injury by Holcik, Martin, Thompson, Charlie S., Yaraghi, Zahra, Lefebvre, Charles A., MacKenzie, Alex E., Korneluk, Robert G.

“…The neuronal apoptosis inhibitory protein (NAIP) is a member of a novel family of inhibitor of apoptosis (IAP) proteins. The IAP genes are highly conserved…”
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Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies by Evgin, Laura, Ilkow, Carolina S, Bourgeois-Daigneault, Marie-Claude, de Souza, Christiano Tanese, Stubbert, Lawton, Huh, Michael S, Jennings, Victoria A, Marguerie, Monique, Acuna, Sergio A, Keller, Brian A, Lefebvre, Charles, Falls, Theresa, Le Boeuf, Fabrice, Auer, Rebecca A, Lambris, John D, McCart, J Andrea, Stojdl, David F, Bell, John C

“…The systemic delivery of therapeutic viruses, such as oncolytic viruses or vaccines, is limited by the generation of neutralizing antibodies. While…”
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La noción de «auctoritas» canónica con respecto a la ley, la costumbre y el uso by Lefebvre, Charles

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SELENE: Self-Monitored Dependable Platform for High-Performance Safety-Critical Systems by Hernandez, Carles, Flieh, Jose, Paredes, Roberto, Lefebvre, Charles-Alexis, Allende, Imanol, Abella, Jaume, Trilla, David, Matschnig, Martin, Fischer, Bernhard, Schwarz, Konrad, Kiszka, Jan, Ronnback, Martin, Klockars, Johan, McGuire, Nicholas, Rammerstorfer, Franz, Schwarzl, Christian, Wartet, Franck, Ludemann, Dierk, Labayen, Mikel

“…Existing HW/SW platforms for safety-critical systems suffer from limited performance and/or from lack of flexibility due to building on specific proprietary…”
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Toward Linux-based safety-critical systems—Execution time variability analysis of Linux system calls by Galarraga, Markel, Lefebvre, Charles-Alexis, Perez-Cerrolaza, Jon, Pascual, Jose A.

“…Modern transportation and industrial domain safety-critical applications, such as autonomous vehicles and collaborative robots, exhibit a combination of…”
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Digital thermal sensor based on ring-oscillators in Zynq SoC technology by Lefebvre, Charles-Alexis, Rubio, Leire, Montero, Jose Luis

“…The impact of the temperature is one of the most critical issues when designing an industrial embedded systems. Plenty of them are centered on a…”
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Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity by Walsh, Scott R, Bastin, Donald, Chen, Lan, Nguyen, Andrew, Storbeck, Christopher J, Lefebvre, Charles, Stojdl, David, Bramson, Jonathan L, Bell, John C, Wan, Yonghong

“…Despite its success in treating melanoma and hematological malignancies, adoptive cell therapy (ACT) has had only limited effects in solid tumors. This is due…”
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