Search Results - "Lefèvre, Pavine L.C"

Exposure to an environmentally relevant mixture of brominated flame retardants affects fetal development in Sprague-Dawley rats by Berger, Robert G, Lefèvre, Pavine L.C, Ernest, Sheila R, Wade, Michael G, Ma, Yi-Qian, Rawn, Dorothea F.K, Gaertner, Dean W, Robaire, Bernard, Hales, Barbara F

“…Abstract Brominated flame retardants are incorporated into a wide variety of consumer products and are known to enter into the surrounding environment, leading…”
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Exposure of Female Rats to an Environmentally Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis1 by Lefèvre, Pavine L.C, Berger, Robert G, Ernest, Sheila R, Gaertner, Dean W, Rawn, Dorothea F.K, Wade, Michael G, Robaire, Bernard, Hales, Barbara F

“…Brominated flame retardants (BFRs) are incorporated into various consumer products to prevent flame propagation. These compounds leach into the domestic…”
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Polybrominated Diphenyl Ethers in Human Follicular Fluid Dysregulate Mural and Cumulus Granulosa Cell Gene Expression by Lefèvre, Pavine L C, Nardelli, Thomas C, Son, Weon-Young, Sadler, Amy R, Rawn, Dorothea F K, Goodyer, Cindy, Robaire, Bernard, Hales, Barbara F

“…Polybrominated diphenyl ethers (PBDEs), a major class of flame retardants incorporated into numerous consumer products, leach out into dust resulting in…”
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Polyamines on the Reproductive Landscape by Lefèvre, Pavine L. C, Palin, Marie-France, Murphy, Bruce D

“…The polyamines are ubiquitous polycationic compounds. Over the past 40 yr, investigation has shown that some of these, namely spermine, spermidine, and…”
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Exposure of Female Rats to an Environmentally Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis by Lefèvre, Pavine L C, Berger, Robert G, Ernest, Sheila R, Gaertner, Dean W, Rawn, Dorothea F K, Wade, Michael G, Robaire, Bernard, Hales, Barbara F

“…Brominated flame retardants (BFRs) are incorporated into various consumer products to prevent flame propagation. These compounds leach into the domestic…”
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Polyamines Are Implicated in the Emergence of the Embryo from Obligate Diapause by Lefèvre, Pavine L. C, Palin, Marie-France, Chen, Gary, Turecki, Gustavo, Murphy, Bruce D

“…Polyamine deprivation maintains embryos in embryonic diapause and induces a delay of the timing of embryo implantation; polyamines are essential to…”
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Gestational and Early Postnatal Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants: General Toxicity and Skeletal Variations by Tung, Emily W. Y., Yan, Han, Lefèvre, Pavine L. C., Berger, Robert G., Rawn, Dorothea F. K., Gaertner, Dean W., Kawata, Alice, Rigden, Marc, Robaire, Bernard, Hales, Barbara F., Wade, Michael G.

“…Brominated flame retardants (BFRs) are stable environmental contaminants known to exert endocrine‐disrupting effects. Developmental exposure to polybrominated…”
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Uterine signaling at the emergence of the embryo from obligate diapause by Lefèvre, Pavine L C, Palin, Marie-France, Beaudry, Danièle, Dobias-Goff, Mira, Desmarais, Joëlle A, Llerena V, Evelyn M, Murphy, Bruce D

“…Embryonic diapause is the reversible arrest of embryo development prior to implantation under a regime of uterine control that is not well understood. Our…”
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Differential gene expression in the uterus and blastocyst during the reactivation of embryo development in a model of delayed implantation by Lefèvre, Pavine L C, Murphy, Bruce D

“…Delayed implantation, a reversible arrest in embryo development while the embryo is at the blastocyst stage, provides an interesting window for observation of…”
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Clinical Pharmacology of Janus Kinase Inhibitors in Inflammatory Bowel Disease by Lefevre, Pavine L C, Vande Casteele, Niels

“…Inflammatory bowel disease, including ulcerative colitis and Crohn's disease, are chronic inflammatory disorders of the gastrointestinal tract which are…”
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A Mixture Reflecting Polybrominated Diphenyl Ether (PBDE) Profiles Detected in Human Follicular Fluid Significantly Affects Steroidogenesis and Induces Oxidative Stress in a Female Human Granulosa Cell Line by Lefevre, Pavine L. C, Wade, Mike, Goodyer, Cindy, Hales, Barbara F, Robaire, Bernard

“…Brominated flame retardants are incorporated into consumer products to prevent flame propagation. These compounds leach into the domestic environment,…”
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In Utero and Lactational Exposure to Flame Retardants Disrupts Rat Ovarian Follicular Development and Advances Puberty by Allais, Adélaïde, Albert, Océane, Lefèvre, Pavine L C, Wade, Michael G, Hales, Barbara F, Robaire, Bernard

“…Abstract Brominated flame retardants (BFRs), including polybrominated diphenyl ethers and hexabromocyclododecane, leach out from consumer products into the…”
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Factors Influencing Drug Disposition of Monoclonal Antibodies in Inflammatory Bowel Disease: Implications for Personalized Medicine by Lefevre, Pavine L. C., Shackelton, Lisa M., Vande Casteele, Niels

“…Monoclonal antibody (mAb) therapies have revolutionized the treatment of several chronic inflammatory diseases, including the inflammatory bowel diseases…”
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A Clinical Prediction Model to Determine Probability of Response to Certolizumab Pegol for Crohn’s Disease by Lefevre, Pavine L. C., Dulai, Parambir S., Wang, Zhongya, Guizzetti, Leonardo, Feagan, Brian G., Pop, Anca, Yassine, Mohamed, Shackelton, Lisa M., Jairath, Vipul, Sandborn, William J., Vande Casteele, Niels

“…Background Certolizumab pegol (CZP) is effective for moderately to severely active Crohn’s disease (CD). Higher plasma concentrations are associated with…”
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Uterine Global Gene Expression During Resumption of Embryo Development Following Delayed Implantation in the Mink by Lefevre, Pavine L.C., Beaudry, Daniele, Palin, Marie-France, Murphy, Bruce D.

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Les voies de signalisation uterines a l'emergence de la diapause embryonnaire chez le vison americain by Lefevre, Pavine L.C

“…Embryonic diapause is characterized by a reversible arrest of blastocyst development prior to implantation and delay in implantation. In the American mink,…”
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