Search Results - "Lees, George E."

Early diagnosis of renal disease and renal failure by Lees, George E

“…The main goal of early diagnosis of renal disease and renal failure in dogs and cats is to enable timely application of therapeutic interventions that may slow…”
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Minimal change glomerulopathy in a cat by Backlund, Brianna, Cianciolo, Rachel E., Cook, Audrey K., Clubb, Fred J., Lees, George E.

“…A 6-year-old domestic shorthair male castrated cat was evaluated for sudden onset of vomiting and anorexia. A diagnosis of hypereosinophilic syndrome (HES) was…”
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Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS) by Rao, Velidi H., Lees, George E., Kashtan, Clifford E., Nemori, Ryochi, Singh, Rakesh K., Meehan, Daniel T., Rodgers, Kathyrn, Berridge, Brian R., Bhattacharya, Gautam, Cosgrove, Dominic

“…Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS). Alport syndrome is a group of…”
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Associations of patient characteristics, disease stage, and biopsy technique with the diagnostic quality of core needle renal biopsy specimens from dogs with suspected kidney disease by Crivellenti, Leandro Z, Cianciolo, Rachel, Wittum, Thomas, Lees, George E, Adin, Christopher A

“…OBJECTIVE To identify factors affecting the diagnostic quality of core needle renal biopsy specimens from dogs with suspected kidney disease. DESIGN…”
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Kidney diseases caused by glomerular basement membrane type IV collagen defects in dogs by Lees, George E.

“…Objective To review the pathogenesis, as well as the clinical and pathologic features of canine glomerular diseases caused by genetic type IV collagen defects…”
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Author Correction: RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy by Chu, Candice P., Hokamp, Jessica A., Cianciolo, Rachel E., Dabney, Alan R., Brinkmeyer-Langford, Candice, Lees, George E., Nabity, Mary B.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy by Chu, Candice P., Hokamp, Jessica A., Cianciolo, Rachel E., Dabney, Alan R., Brinkmeyer-Langford, Candice, Lees, George E., Nabity, Mary B.

“…Dogs with X-linked hereditary nephropathy (XLHN) have a glomerular basement membrane defect that leads to progressive juvenile-onset renal failure. Their…”
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Assessment and management of proteinuria in dogs and cats: 2004 ACVIM Forum Consensus Statement (small animal) by Lees, George E, Brown, Scott A, Elliott, Jonathan, Grauer, Gregory E, Vaden, Shelly L

“…Emerging data indicate that more attention should be given to the detection, evaluation, monitoring, and treatment of dogs and cats with proteinuria. The…”
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Glomerular Lipidosis in Dogs by Kohnken, Rebecca A., Amerman, Hayley, Brown, Cathy A., Furrow, Eva, Lees, George E., Cianciolo, Rachel E.

“…Glomerular lipidosis (GL) is characterized by dilated glomerular capillary loops containing lipid-laden cells (foam cells). Previously, GL was considered to be…”
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Pathology in Practice by Martinez, Michael P, Cianciolo, Rachel E, Foster, Jonathan D, Lees, George E

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Effects of serial ultrasound-guided renal biopsies on kidneys of healthy adolescent dogs by Groman, R.P, Bahr, A, Berridge, B.R, Lees, G.E

“…Ten healthy mixed‐breed dogs were used to evaluate the functional and structural effects of serial ultrasound‐guided renal biopsies obtained with an automated…”
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The effect of progressive glomerular disease on megalin-mediated endocytosis in the kidney by Vinge, Lotte, Lees, George E., Nielsen, Rikke, Kashtan, Clifford E., Bahr, Anne, Christensen, Erik I.

“…Background. A well-characterized dog model of the X-linked collagen disease Alport syndrome (XLAS) was used to study the effect of progressive glomerular…”
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X-inactivation modifies disease severity in female carriers of murine X-linked Alport syndrome by Rheault, Michelle N., Kren, Stefan M., Hartich, Linda A., Wall, Melanie, Thomas, William, Mesa, Hector A., Avner, Philip, Lees, George E., Kashtan, Clifford E., Segal, Yoav

“…Background. Female carriers of X-linked Alport syndrome (XLAS) demonstrate variability in clinical phenotype that, unlike males, cannot be correlated with…”
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Proteomic analysis of urine from male dogs during early stages of tubulointerstitial injury in a canine model of progressive glomerular disease by Nabity, Mary B., Lees, George E., Dangott, Lawrence J., Cianciolo, Rachel, Suchodolski, Jan S., Steiner, Jörg M.

“…Background: Sensitive and specific noninvasive biomarkers for tubulointerstitial injury are lacking, and proteomic techniques provide a powerful tool for…”
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Renal biopsy: a retrospective study of methods and complications in 283 dogs and 65 cats by Vaden, S.L, Levine, J.F, Lees, G.E, Groman, R.P, Grauer, G.F, Forrester, S.D

“…Renal biopsy often is required to establish a definitive diagnosis in dogs and cats with renal disease. In this retrospective study, we determined the…”
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Evaluation of perinuclear anti-neutrophilic cytoplasmic autoantibodies as an early marker of protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers by Allenspach, Karin, Lomas, Bethany, Wieland, Barbara, Harris, Tonya, Pressler, Barrak, Mancho, Carolina, Lees, George E, Vaden, Shelly L

“…To evaluate perinuclear anti-neutrophilic cytoplasmic autoantibody (pANCA) status in Soft Coated Wheaten Terriers (SCWTs) and SCWT-Beagle crossbred dogs and to…”
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Renal Biopsy and Pathologic Evaluation of Glomerular Disease by Lees, George E., Cianciolo, Rachel E., Clubb, Fred J.

“…Presence of suspected primary glomerular disease is the most common and compelling reason to consider renal biopsy. Pathologic findings in samples from animals…”
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Stability of canine pancreatic lipase immunoreactivity concentration in serum samples and effects of long-term administration of prednisone to dogs on serum canine pancreatic lipase immunoreactivity concentrations by Steiner, Jorg M, Teague, Shelia R, Lees, George E, Willard, Michael D, Williams, David A, Ruaux, Craig G

“…To evaluate stability of canine pancreatic lipase immunoreactivity (cPLI) in serum samples and to determine the effect of long-term administration of…”
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Long-chain (n-3) polyunsaturated fatty acids are more efficient than alpha-linolenic acid in improving electroretinogram responses of puppies exposed during gestation, lactation, and weaning by Heinemann, Kimberly M, Waldron, Mark K, Bigley, Karen E, Lees, George E, Bauer, John E

“…Long-chain PUFAs (LCPUFAs) are essential for proper neural and retinal development in many mammalian species. We investigated puppies born to dogs fed diets…”
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Resolution of a proteinuric nephropathy associated with Babesia gibsoni infection in a dog by Slade, Dennis J, Lees, George E, Berridge, Brian R, Clubb, Fred J, Kuczynski, Leslie A, Littman, Meryl P

“…A 4 yr old male castrated Labrador retriever was evaluated for a short history of inappetance, lethargy, small-bowel diarrhea, polyuria, and polydipsia…”
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