Search Results - "Lees, Emily A."
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An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
Published in Nature communications (19-09-2019)“…Bloodstream infections by Salmonella enterica serovar Typhimurium constitute a major health burden in sub-Saharan Africa (SSA). These invasive non-typhoidal…”
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Inhibitory Concentrations of Ciprofloxacin Induce an Adaptive Response Promoting the Intracellular Survival of Salmonella enterica Serovar Typhimurium
Published in mBio (29-06-2021)“…Antimicrobial resistance (AMR) is a pressing global health crisis, which has been fueled by the sustained use of certain classes of antimicrobials, including…”
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Infant postnatal prophylaxis following maternal viraemia during breastfeeding
Published in AIDS (London) (01-06-2023)Get full text
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Changes to the UK childhood immunisation schedule
Published in Archives of disease in childhood (26-09-2024)“…The UK schedule (table 1), which is recognised internationally for its innovation and responsiveness, has been informed by expert review from the Joint…”
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Epidemiology and Management of Pediatric Group A Streptococcal Pneumonia With Parapneumonic Effusion: An Observational Study
Published in The Pediatric infectious disease journal (01-09-2024)“…During autumn/winter 2022, UK pediatricians reported an unseasonal increase in invasive group A streptococcal infections; a striking proportion presenting with…”
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Intracranial Empyema in Children: A Single-center Retrospective Case Series
Published in The Pediatric infectious disease journal (01-11-2023)“…We conducted a retrospective, observational study of 42 children with intracranial empyema admitted to a pediatric neurosurgical center over a 9-year period…”
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PULMONARY CYSTIC ECHINOCOCCOSIS IN A CHILD PRESENTING IN THE UNITED KINGDOM WITH FEVER AND CHEST PAIN: A BRIEF REPORT AND DISCUSSION ON MANAGEMENT
Published in The Pediatric infectious disease journal (01-09-2023)“…Cystic echinococcosis is a zoonosis caused by the larvae of Echinococcus granulosus. Pulmonary disease may be asymptomatic until the cyst ruptures or becomes…”
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Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells
Published in Proceedings of the National Academy of Sciences - PNAS (02-10-2018)“…Intestinal epithelial cells (IECs) play a key role in regulating immune responses and controlling infection. However, the direct role of IECs in restricting…”
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Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens
Published in Journal of visualized experiments (12-05-2019)“…The intestinal 'organoid' (iHO) system, wherein 3-D structures representative of the epithelial lining of the human gut can be produced from human induced…”
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Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens
Published in BMC infectious diseases (19-06-2014)“…According to the World Health Organisation, influenza A (2009 pdmH1N1) has moved into the post-pandemic phase, but there were still high numbers of infections…”
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Treating invasive Group A Streptococcal infections
Published in Paediatrics and child health (01-06-2014)“…Abstract Streptococcus pyogenes is a gram-positive, beta-haemolytic bacterium, commonly responsible for acute pharyngitis and skin infections. It has the…”
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