Search Results - "Leenen, Pieter J M"

Decreased serum level of miR-146a as sign of chronic inflammation in type 2 diabetic patients by Baldeón R, Lucy, Weigelt, Karin, de Wit, Harm, Ozcan, Behiye, van Oudenaren, Adri, Sempértegui, Fernando, Sijbrands, Eric, Grosse, Laura, Freire, Wilma, Drexhage, Hemmo A, Leenen, Pieter J M

“…There is increasing evidence that chronic inflammation is an important determinant in insulin resistance and in the pathogenesis of type 2 diabetes (T2D)…”
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The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function by Kannegieter, Nynke M, Hesselink, Dennis A, Dieterich, Marjolein, Kraaijeveld, Rens, Rowshani, Ajda T, Leenen, Pieter J M, Baan, Carla C

“…Monocytes and macrophages play key roles in many disease states, including cellular and humoral rejection after solid organ transplantation (SOT). To suppress…”
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Brown Seaweed Food Supplementation: Effects on Allergy and Inflammation and Its Consequences by Olsthoorn, Simone E. M, Wang, Xi, Tillema, Berend, Vanmierlo, Tim, Kraan, Stefan, Leenen, Pieter J. M, Mulder, Monique T

“…Multiple health benefits have been ascribed to brown seaweeds that are used traditionally as dietary component mostly in Asia. This systematic review…”
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Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes by Abadie, Valérie, Badell, Edgar, Douillard, Patrice, Ensergueix, Danielle, Leenen, Pieter J.M., Tanguy, Myriam, Fiette, Laurence, Saeland, Sem, Gicquel, Brigitte, Winter, Nathalie

“…The early innate response after Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccination is poorly characterized but probably decisive for subsequent…”
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Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response by Sunderkotter, Cord, Nikolic, Tatjana, Dillon, Marilyn J, van Rooijen, Nico, Stehling, Martin, Drevets, Douglas A, Leenen, Pieter J. M

“…Blood monocytes are well-characterized precursors for macrophages and dendritic cells. Subsets of human monocytes with differential representation in various…”
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IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation by Razawy, Wida, Alves, Celso H., Koedam, Marijke, Asmawidjaja, Patrick S., Mus, Adriana M. C., Oukka, Mohamed, Leenen, Pieter J. M., Visser, Jenny A., van der Eerden, Bram C. J., Lubberts, Erik

“…The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate…”
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Systemic Listeria monocytogenes infection in aged mice induces long-term neuroinflammation: the role of miR-155 by Cassidy, Benjamin R, Sonntag, William E, Leenen, Pieter J M, Drevets, Douglas A

“…Understanding mechanisms of pathologic neuroinflammation is essential for improving outcomes after central nervous system infections. Brain tissue-resident…”
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S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll‐like receptor 4: Implications for bone destruction in murine antigen‐induced arthritis by Grevers, Lilyanne C., de Vries, Teun J., Vogl, Thomas, Abdollahi‐Roodsaz, Shahla, Sloetjes, Annet W., Leenen, Pieter J. M., Roth, Johannes, Everts, Vincent, van den Berg, Wim B., van Lent, Peter L. E. M.

“…Objective Rheumatoid arthritis, which is associated with elevated levels of S100A8 and S100A9, is characterized by severe bone erosions caused by enhanced…”
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Type 2 Diabetes Monocyte MicroRNA and mRNA Expression: Dyslipidemia Associates with Increased Differentiation-Related Genes but Not Inflammatory Activation by Baldeón R, Lucy, Weigelt, Karin, de Wit, Harm, Ozcan, Behiye, van Oudenaren, Adri, Sempértegui, Fernando, Sijbrands, Eric, Grosse, Laura, van Zonneveld, Anton-Jan, Drexhage, Hemmo A, Leenen, Pieter J M

“…To study the expression pattern of microRNAs and mRNAs related to inflammation in T2D monocytes. A microRNA finding study on monocytes of T2D patients and…”
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Gr‐1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid‐derived suppressor cell activity in BM cells by Ribechini, Eliana, Leenen, Pieter J. M., Lutz, Manfred B.

“…The Gr‐1 (RB6‐8C5) Ab binds with high affinity to mouse Ly‐6G molecules and to a lower extent to Ly‐6C and has been widely used for cell depletion in infected…”
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Invasion of the Central Nervous System by Intracellular Bacteria by DREVETS, Douglas A, LEENEN, Pieter J. M, GREENFIELD, Ronald A

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage by Maarten Egeler, R, van Halteren, Astrid G.S, Hogendoorn, Pancras C.W, Laman, Jon D, Leenen, Pieter J.M

“…In its rare occurrence, Langerhans cell histiocytosis (LCH) is a dangerous but intriguing deviation of mononuclear phagocytes, especially dendritic cells…”
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Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation by Raes, G, Brys, L, Dahal, B K, Brandt, J, Grooten, J, Brombacher, F, Vanham, G, Noel, W, Bogaert, P, Boonefaes, T, Kindt, A, Van den Bergh, R, Leenen, PJM, De Baetselier, P, Ghassabeh, G H

“…Molecular markers, especially surface markers associated with type II, cytokine‐dependent, alternatively activated macrophages (aaMF), remain scarce. Besides…”
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Nomenclature of monocytes and dendritic cells in blood by Ziegler-Heitbrock, Loems, Ancuta, Petronela, Crowe, Suzanne, Dalod, Marc, Grau, Veronika, Hart, Derek N., Leenen, Pieter J.M., Liu, Yong-Jun, MacPherson, Gordon, Randolph, Gwendalyn J., Scherberich, Juergen, Schmitz, Juergen, Shortman, Ken, Sozzani, Silvano, Strobl, Herbert, Zembala, Marek, Austyn, Jonathan M., Lutz, Manfred B.

“…Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions,…”
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Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis by Hofkens, Wouter, Grevers, Lilyanne C., Walgreen, Birgitte, de Vries, Teun J., Leenen, Pieter J.M., Everts, Vincent, Storm, Gert, van den Berg, Wim B., van Lent, Peter L.

“…The objective of this study was to determine the effect of systemic delivery of prednisolone phosphate (PLP) encapsulated within long circulating ‘stealth’…”
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Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging? by van Beek, Adriaan A., Van den Bossche, Jan, Mastroberardino, Pier G., de Winther, Menno P.J., Leenen, Pieter J.M.

“…Aging is a complex process with an impact on essentially all organs. Declined cellular repair causes increased damage at genomic and proteomic levels upon…”
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The kinetics of plasmacytoid dendritic cell accumulation in the pancreas of the NOD mouse during the early phases of insulitis by Welzen-Coppens, Jojanneke M C, van Helden-Meeuwsen, Cornelia G, Leenen, Pieter J M, Drexhage, Hemmo A, Versnel, Marjan A

“…In non-obese diabetic (NOD) mice that spontaneously develop autoimmune diabetes, plasmacytoid dendritic cells (pDCs) have a diabetes-promoting role through…”
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Chorionic gonadotropin induces dendritic cells to express a tolerogenic phenotype by Wan, Hui, Versnel, Marjan A, Leijten, Lonneke M E, van Helden-Meeuwsen, Cornelia G, Fekkes, Durk, Leenen, Pieter J M, Khan, Nisar A, Benner, Robbert, Kiekens, Rebecca C M

“…The pregnancy hormone human chorionic gonadotropin (hCG) has been suggested to play an immunoregulatory role in addition to its endocrine function, thus…”
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Chorionic gonadotropin can enhance innate immunity by stimulating macrophage function by Wan, Hui, Versnel, Marjan A., Cheung, Wai yee, Leenen, Pieter J. M., Khan, Nisar A., Benner, Robbert, Kiekens, Rebecca C. M.

“…Human chorionic gonadotropin (hCG) is a placental glycoprotein, mainly secreted by trophoblasts during pregnancy. Its function in endocrine regulation has been…”
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Synthetic Human Chorionic Gonadotropin–Related Oligopeptides Impair Early Innate Immune Responses to Listeria monocytogenes in Mice by van der Zee, Marten, Dik, William A., Kap, Yolanda S., Dillon, Marilyn J., Benner, Robbert, Leenen, Pieter J. M., Khan, Nisar A., Drevets, Douglas A.

“…Background. Synthetic human chorionic gonadotropin (hCG)–related oligopeptides are potent inhibitors of pathogenic inflammatory responses induced by in vivo…”
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