Search Results - "Leenen, M"

Decreased serum level of miR-146a as sign of chronic inflammation in type 2 diabetic patients by Baldeón R, Lucy, Weigelt, Karin, de Wit, Harm, Ozcan, Behiye, van Oudenaren, Adri, Sempértegui, Fernando, Sijbrands, Eric, Grosse, Laura, Freire, Wilma, Drexhage, Hemmo A, Leenen, Pieter J M

“…There is increasing evidence that chronic inflammation is an important determinant in insulin resistance and in the pathogenesis of type 2 diabetes (T2D)…”
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The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function by Kannegieter, Nynke M, Hesselink, Dennis A, Dieterich, Marjolein, Kraaijeveld, Rens, Rowshani, Ajda T, Leenen, Pieter J M, Baan, Carla C

“…Monocytes and macrophages play key roles in many disease states, including cellular and humoral rejection after solid organ transplantation (SOT). To suppress…”
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Nomenclature of monocytes and dendritic cells in blood by Ziegler-Heitbrock, Loems, Ancuta, Petronela, Crowe, Suzanne, Dalod, Marc, Grau, Veronika, Hart, Derek N., Leenen, Pieter J.M., Liu, Yong-Jun, MacPherson, Gordon, Randolph, Gwendalyn J., Scherberich, Juergen, Schmitz, Juergen, Shortman, Ken, Sozzani, Silvano, Strobl, Herbert, Zembala, Marek, Austyn, Jonathan M., Lutz, Manfred B.

“…Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions,…”
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Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes by Abadie, Valérie, Badell, Edgar, Douillard, Patrice, Ensergueix, Danielle, Leenen, Pieter J.M., Tanguy, Myriam, Fiette, Laurence, Saeland, Sem, Gicquel, Brigitte, Winter, Nathalie

“…The early innate response after Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccination is poorly characterized but probably decisive for subsequent…”
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Brown Seaweed Food Supplementation: Effects on Allergy and Inflammation and Its Consequences by Olsthoorn, Simone E. M, Wang, Xi, Tillema, Berend, Vanmierlo, Tim, Kraan, Stefan, Leenen, Pieter J. M, Mulder, Monique T

“…Multiple health benefits have been ascribed to brown seaweeds that are used traditionally as dietary component mostly in Asia. This systematic review…”
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Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response by Sunderkotter, Cord, Nikolic, Tatjana, Dillon, Marilyn J, van Rooijen, Nico, Stehling, Martin, Drevets, Douglas A, Leenen, Pieter J. M

“…Blood monocytes are well-characterized precursors for macrophages and dendritic cells. Subsets of human monocytes with differential representation in various…”
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Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers by Geurts-Giele, Willemina RR, Leenen, Celine HM, Dubbink, Hendrikus J, Meijssen, Isabelle C, Post, Edward, Sleddens, Hein FBM, Kuipers, Ernst J, Goverde, Anne, van den Ouweland, Ans MW, van Lier, Margot GF, Steyerberg, Ewout W, van Leerdam, Monique E, Wagner, Anja, Dinjens, Winand NM

“…Lynch syndrome (LS) is caused by germline mutations in mismatch repair (MMR) genes, resulting in microsatellite‐unstable tumours. Approximately 35% of…”
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Printable electronics: flexibility for the future by Leenen, Mark A. M., Arning, Volker, Thiem, Heiko, Steiger, Jürgen, Anselmann, Ralf

“…Printed electronics is an emerging technology with huge potential. Market studies predict a multi‐billion dollar market size within less than 5 years. Due to…”
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Obesity-associated T-cell and macrophage activation improve partly after a lifestyle intervention by van der Zalm, I. J. B., van der Valk, E. S., Wester, V. L., Nagtzaam, N. M. A., van Rossum, E. F. C., Leenen, P. J. M., Dik, W. A.

“…Background The relation between low-grade inflammation and metabolic dysfunction in obesity is not fully explored. Objective To evaluate immune parameters in…”
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Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases by Mourik, Bas C, Lubberts, Erik, de Steenwinkel, Jurriaan E M, Ottenhoff, Tom H M, Leenen, Pieter J M

“…The classical paradigm of tuberculosis (TB) immunity, with a central protective role for Th1 responses and IFN-γ-stimulated cellular responses, has been…”
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Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function by van der Spek, Anne H, Surovtseva, Olga V, Jim, Kin Ki, van Oudenaren, Adri, Brouwer, Matthijs C, Vandenbroucke-Grauls, Christina M J E, Leenen, Pieter J M, van de Beek, Diederik, Hernandez, Arturo, Fliers, Eric, Boelen, Anita

“…Innate immune cells, including macrophages, have recently been identified as target cells for thyroid hormone. We hypothesized that optimal intracellular…”
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The Impact of Obesity and Lifestyle on the Immune System and Susceptibility to Infections Such as COVID-19 by de Frel, Daan L, Atsma, Douwe E, Pijl, Hanno, Seidell, Jacob C, Leenen, Pieter J M, Dik, Willem A, van Rossum, Elisabeth F C

“…COVID-19 is a global challenge to healthcare. Obesity is common in patients with COVID-19 and seems to aggravate disease prognosis. In this review we explore…”
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Gr‐1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid‐derived suppressor cell activity in BM cells by Ribechini, Eliana, Leenen, Pieter J. M., Lutz, Manfred B.

“…The Gr‐1 (RB6‐8C5) Ab binds with high affinity to mouse Ly‐6G molecules and to a lower extent to Ly‐6C and has been widely used for cell depletion in infected…”
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Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages by Movita, Dowty, Kreefft, Kim, Biesta, Paula, Oudenaren, Adri, Leenen, Pieter J. M., Janssen, Harry L. A., Boonstra, Andre

“…Kupffer cells are endocytic, yet weak producers of proinflammatory cytokines, as compared against splenic and peritoneal macrophages. The immunostimulatory…”
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IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation by Razawy, Wida, Alves, Celso H., Koedam, Marijke, Asmawidjaja, Patrick S., Mus, Adriana M. C., Oukka, Mohamed, Leenen, Pieter J. M., Visser, Jenny A., van der Eerden, Bram C. J., Lubberts, Erik

“…The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate…”
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Genetic testing for Lynch syndrome: family communication and motivation by Leenen, Celine H. M., Heijer, Mariska den, van der Meer, Conny, Kuipers, Ernst J., van Leerdam, Monique E., Wagner, Anja

“…Current genetic counselling practice for Lynch syndrome (LS) relies on diagnosed index patients to inform their biological family about LS, referred to as the…”
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Systemic Listeria monocytogenes infection in aged mice induces long-term neuroinflammation: the role of miR-155 by Cassidy, Benjamin R, Sonntag, William E, Leenen, Pieter J M, Drevets, Douglas A

“…Understanding mechanisms of pathologic neuroinflammation is essential for improving outcomes after central nervous system infections. Brain tissue-resident…”
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S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll‐like receptor 4: Implications for bone destruction in murine antigen‐induced arthritis by Grevers, Lilyanne C., de Vries, Teun J., Vogl, Thomas, Abdollahi‐Roodsaz, Shahla, Sloetjes, Annet W., Leenen, Pieter J. M., Roth, Johannes, Everts, Vincent, van den Berg, Wim B., van Lent, Peter L. E. M.

“…Objective Rheumatoid arthritis, which is associated with elevated levels of S100A8 and S100A9, is characterized by severe bone erosions caused by enhanced…”
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Investigation of the Living Cationic Ring-Opening Polymerization of 2-Methyl-, 2-Ethyl-, 2-Nonyl-, and 2-Phenyl-2-oxazoline in a Single-Mode Microwave Reactor by Wiesbrock, Frank, Hoogenboom, Richard, Leenen, Mark A. M., Meier, Michael A. R., Schubert, Ulrich S.

“…The living cationic ring-opening polymerizations of 2-methyl-, 2-ethyl-, 2-nonyl-, and 2-phenyl-2-oxazoline were performed in acetonitrile at high temperatures…”
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Type 2 Diabetes Monocyte MicroRNA and mRNA Expression: Dyslipidemia Associates with Increased Differentiation-Related Genes but Not Inflammatory Activation by Baldeón R, Lucy, Weigelt, Karin, de Wit, Harm, Ozcan, Behiye, van Oudenaren, Adri, Sempértegui, Fernando, Sijbrands, Eric, Grosse, Laura, van Zonneveld, Anton-Jan, Drexhage, Hemmo A, Leenen, Pieter J M

“…To study the expression pattern of microRNAs and mRNAs related to inflammation in T2D monocytes. A microRNA finding study on monocytes of T2D patients and…”
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