Search Results - "Leenaars, Cathalijn"

Animal to human translation: a systematic scoping review of reported concordance rates by Leenaars, Cathalijn H C, Kouwenaar, Carien, Stafleu, Frans R, Bleich, André, Ritskes-Hoitinga, Merel, De Vries, Rob B M, Meijboom, Franck L B

“…Drug development is currently hampered by high attrition rates; many developed treatments fail during clinical testing. Part of the attrition may be due to low…”
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A systematic review of animal and human data comparing the nasal potential difference test between cystic fibrosis and control by Leenaars, Cathalijn H. C., Stafleu, Frans R., Häger, Christine, Nieraad, Hendrik, Bleich, André

“…The nasal potential difference test (nPD) is an electrophysiological measurement which is altered in patients and animal models with cystic fibrosis (CF)…”
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Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review by Dirven, Hubert, Vist, Gunn E., Bandhakavi, Sricharan, Mehta, Jyotsna, Fitch, Seneca E., Pound, Pandora, Ram, Rebecca, Kincaid, Breanne, Leenaars, Cathalijn H. C., Chen, Minjun, Wright, Robert A., Tsaioun, Katya

“…Drug-induced liver injury (DILI) causes one in three market withdrawals due to adverse drug reactions, causing preventable human suffering and massive…”
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Methodical advances in reproducibility research: A proof of concept qualitative comparative analysis of reproducing animal data in humans by Leenaars, Cathalijn H.C., Teerenstra, Steven, Meijboom, Franck L.B., Bleich, André

“…While the term reproducibility crisis mainly reflects reproducibility of experiments between laboratories, reproducibility between species also remains…”
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Addressing the challenges of reconstructing systematic reviews datasets: a case study and a noisy label filter procedure by Neeleman, Rutger, Leenaars, Cathalijn H C, Oud, Matthijs, Weijdema, Felix, van de Schoot, Rens

“…Systematic reviews and meta-analyses typically require significant time and effort. Machine learning models have the potential to enhance screening efficiency…”
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A systematic review and meta-analysis of animal models of binge eating - Part 1: Definitions and food/drink intake outcomes by Rehn, Simone, Raymond, Joel S., Boakes, Robert A., Leenaars, Cathalijn H.C.

“…•Many publications fail to report operational definitions of bingeing in animals.•Face validity is limited in some models that report binge-like…”
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Software tools for literature screening in systematic reviews in biomedical research by Van der Mierden, Stevie, Tsaioun, Katya, Bleich, André, Leenaars, Cathalijn H C

“…Systematic Reviews (SRs) hold promise for implementing the 3Rs in animal sciences: they can retrieve available alternative models, help refining experiments,…”
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A systematic mapping review of the evolution of the rat Forced Swim Test: Protocols and outcome parameters by Brandwein, Christiane, Leenaars, Cathalijn H.C., Becker, Laura, Pfeiffer, Natascha, Iorgu, Ana-Maria, Hahn, Melissa, Vairani, Gaia A., Lewejohann, Lars, Bleich, André, Mallien, Anne S., Gass, Peter

“…As depression is projected to become the leading mental disease burden globally by 2030, understanding the underlying pathology, as well as screening potential…”
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Summer School for Systematic Reviews of Animal Studies: Fostering Evidence-Based and Rigorous Animal Research by Rosso, Marianna, Doneva, Simona E, Howells, David W, Leenaars, Cathalijn H.C, Ineichen, Benjamin V

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Extracting data from graphs: A case‐study on animal research with implications for meta‐analyses by Van der Mierden, Stevie, Spineli, Loukia Maria, Talbot, Steven R., Yiannakou, Christina, Zentrich, Eva, Weegh, Nora, Struve, Birgitta, Zur Brügge, Talke Friederike, Bleich, André, Leenaars, Cathalijn H.C.

“…Systematic reviews with meta‐analyses are powerful tools that can answer research questions based on data from published studies. Ideally, all relevant data is…”
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The Leeds food preference questionnaire after mild sleep restriction — A small feasibility study by Leenaars, Cathalijn H.C, Zant, Janneke C, Aussems, Audrey, Faatz, Vivian, Snackers, Daphne, Kalsbeek, Andries

“…Abstract Besides the increased sedentary lifestyle and increased caloric intake, changes in dietary composition may play an important role in the increased…”
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Laboratory animals search filter for different literature databases: PubMed, Embase, Web of Science and PsycINFO by van der Mierden, Stevie, Hooijmans, Carlijn R, Tillema, Alice Hj, Rehn, Simone, Bleich, André, Leenaars, Cathalijn Hc

“…Systematic reviews are important tools in animal research, but the ever-increasing number of studies makes retrieval of all relevant publications challenging…”
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A case study of the informative value of risk of bias and reporting quality assessments for systematic reviews by Leenaars, Cathalijn H C, Stafleu, Frans R, Häger, Christine, Bleich, André

“…While undisputedly important, and part of any systematic review (SR) by definition, evaluation of the risk of bias within the included studies is one of the…”
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Comprehensive search filters for retrieving publications on nonhuman primates for literature reviews (filterNHP) by Cassidy, Lauren C., Leenaars, Cathalijn H. C., Rincon, Alan V., Pfefferle, Dana

“…Nonhuman primates (NHPs) are widely studied across many scientific disciplines using a variety of techniques in diverse environments. Due to the wide scope of…”
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Intracerebral microdialysis of adenosine and adenosine monophosphate – a systematic review and meta‐regression analysis of baseline concentrations by Mierden, Stevie, Savelyev, Sergey A., IntHout, Joanna, Vries, Rob B. M., Leenaars, Cathalijn H. C.

“…Microdialysis is a method to study the extracellular space in vivo, based on the principle of diffusion. It can be used to measure various small molecules…”
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Effects of sleep deprivation on maternal behaviour in animal models: A systematic review and meta‐analysis by Pires, Gabriel N., Oliveira, Thainá B., Mello, Victoria F. F., Bezerra, Andréia G., Leenaars, Cathalijn H. C., Ritskes‐Hoitinga, Merel, Tufik, Sergio, Andersen, Monica L.

“…Summary Pregnancy is a period of numerous physical and emotional changes in women’s lives, including alterations in sleep patterns and worsening of…”
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Measuring endogenous corticosterone in laboratory mice - a mapping review, meta-analysis, and open source database by Van der Mierden, Stevie, Leenaars, Cathalijn H C, Boyle, Erin C, Ripoli, Florenza L, Gass, Peter, Durst, Mattea, Goerlich-Jansson, Vivian C, Jirkof, Paulin, Keubler, Lydia M, Talbot, Steven R, Habedank, Anne, Lewejohann, Lars, Tolba, Rene H, Bleich, André

“…Evaluating stress in laboratory animals is a key principle in animal welfare. Measuring corticosterone is a common method to assess stress in laboratory mice…”
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Brain Microdialysate Monoamines in Relation to Circadian Rhythms, Sleep, and Sleep Deprivation - a Systematic Review, Network Meta-analysis, and New Primary Data by Menon, Julia M L, Nolten, Christ, Achterberg, E J Marijke, Joosten, Ruud N J M A, Dematteis, Maurice, Feenstra, Matthijs G P, Drinkenburg, W H Pim, Leenaars, Cathalijn H C

“…Disruption of the monoaminergic system, e.g. by sleep deprivation (SD), seems to promote certain diseases. Assessment of monoamine levels over the circadian…”
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Development of a Systematic Review Protocol and a Scoping Review of Ultrasound-Induced Immune Effects in Peripheral Tumors by Rix, Anne, Girbig, Renée, Porte, Céline, Lederle, Wiltrud, Leenaars, Cathalijn, Kiessling, Fabian

“…Purpose Publication numbers reporting that ultrasound can stimulate immune reactions in tumors steadily increase. However, the presented data are partially…”
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Intracerebral Adenosine During Sleep Deprivation: A Meta-Analysis and New Experimental Data by Leenaars, Cathalijn H C, Savelyev, Sergey A, Van der Mierden, Stevie, Joosten, Ruud N J M A, Dematteis, Maurice, Porkka-Heiskanen, Tarja, Feenstra, Matthijs G P

“…The neuroregulator adenosine is involved in sleep-wake control. Basal forebrain (BF) adenosine levels increase during sleep deprivation. Only a few studies…”
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