Search Results - "Leena, K"

Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers by Spencer, Sarah J, Tamminen, Manu V, Preheim, Sarah P, Guo, Mira T, Briggs, Adrian W, Brito, Ilana L, A Weitz, David, Pitkänen, Leena K, Vigneault, Francois, Virta, Marko PJuhani, Alm, Eric J

“…Many microbial communities are characterized by high genetic diversity. 16S ribosomal RNA sequencing can determine community members, and metagenomics can…”
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The Resistome of Farmed Fish Feces Contributes to the Enrichment of Antibiotic Resistance Genes in Sediments below Baltic Sea Fish Farms by Muziasari, Windi I, Pitkänen, Leena K, Sørum, Henning, Stedtfeld, Robert D, Tiedje, James M, Virta, Marko

“…Our previous studies showed that particular antibiotic resistance genes (ARGs) were enriched locally in sediments below fish farms in the Northern Baltic Sea,…”
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Bacterial vaginosis, vulvovaginal candidiasis and trichomonal vaginitis among reproductive-aged women seeking primary healthcare in Sana'a city, Yemen by Abdul-Aziz, Maha, Mahdy, Mohammed A K, Abdul-Ghani, Rashad, Alhilali, Nuha A, Al-Mujahed, Leena K A, Alabsi, Salma A, Al-Shawish, Fatima A M, Alsarari, Noura J M, Bamashmos, Wala, Abdulwali, Shahad J H, Al Karawani, Mahdi, Almikhlafy, Abdullah A

“…In Yemen, the underlying causes of infectious vaginitis have been neglected. Therefore, this study aimed to determine the prevalence and risk factors…”
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Unraveling the prevalence of various signalling pathways in non-small-cell lung cancer: a review by Nair, Aathira Sujathan, Jayan, Ajay P., Anandu, K R, Saiprabha, V N, Pappachen, Leena K.

“…Cancer has become a huge public health issue all around the world. The focus of research is on innovative cancer therapy techniques that include the disease's…”
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Pharmacological interventions for sleepiness and sleep disturbances caused by shift work by Liira, Juha, Verbeek, Jos H, Costa, Giovanni, Driscoll, Tim R, Sallinen, Mikael, Isotalo, Leena K, Ruotsalainen, Jani H

“…Shift work results in sleep-wake disturbances, which cause sleepiness during night shifts and reduce sleep length and quality in daytime sleep after the night…”
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Health and health behaviours in adolescence as predictors of education and socioeconomic status in adulthood - a longitudinal study by Koivusilta, Leena K, Acacio-Claro, Paulyn Jean, Mattila, Ville M, Rimpelä, Arja H

“…The positive association of health with education level and socioeconomic status (SES) is well-established. Two theoretical frameworks have been delineated to…”
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A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy by Sasikumar, Pottayil G, Ramachandra, Raghuveer K, Adurthi, Srinivas, Dhudashiya, Amit A, Vadlamani, Sureshkumar, Vemula, Koteswararao, Vunnum, Sriharibabu, Satyam, Leena K, Samiulla, Dodderi S, Subbarao, Krishnaprasad, Nair, Rashmi, Shrimali, Rajeev, Gowda, Nagaraj, Ramachandra, Murali

“…Pioneering success of antibodies targeting immune checkpoints such as PD-1 and CTLA4 has opened novel avenues for cancer immunotherapy. Along with impressive…”
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The Influence of Adolescent health-related Behaviors on Degenerative Low Back Pain Hospitalizations and Surgeries in Adulthood: A Longitudinal Study by Vaajala, Matias, Teuho, Alisa, Liukkonen, Rasmus, Ponkilainen, Ville, Rimpelä, Arja, Koivusilta, Leena K, Mattila, Ville M

“…Retrospective longitudinal study. This study aims to investigate the influence of adolescent health-related behaviors (physical activity, high BMI,…”
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Direct vertical transmission of ESBL/pAmpC-producing Escherichia coli limited in poultry production pyramid by Oikarainen, Paula E., Pohjola, Leena K., Pietola, Eeva S., Heikinheimo, Annamari

“…•Direct vertical transmission of resistant bacteria from parent birds to offspring is limited.•Egg surfaces are free from E. coli after the incubation period…”
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Country-Level Investment in Cultural Opportunity Structures. A Potential Source of Health Differences Between 21 European Countries by Koivusilta, Leena K.

“…Individual’s participation in cultural activities may positively affect health through a pathway mediated by social capital. We examine whether country-level…”
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30-year trends in asthma and the trends in relation to hospitalization and mortality by Pelkonen, Margit K., Notkola, Irma-Leena K., Laatikainen, Tiina K., Jousilahti, Pekka

“…The present study examines how trends in the prevalence of asthma during the past three decades associate with hospitalization and mortality during the same…”
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Association between adolescent lifestyle factors and high-energy traumas in early adulthood: A longitudinal study by Vaajala, Matias, Teuho, Alisa, Liukkonen, Rasmus, Ponkilainen, Ville, Rimpelä, Arja, Koivusilta, Leena K., Mattila, Ville M.

“…•Smoking, monthly drunkenness, and chronic diseases in adolescence increased the risk of high-energy traumas in adulthood.•Low education level in adulthood…”
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Structural Modifications on Chalcone Framework for Developing New Class of Cholinesterase Inhibitors by George, Ginson, Koyiparambath, Vishal Payyalot, Sukumaran, Sunitha, Nair, Aathira Sujathan, Pappachan, Leena K, Al-Sehemi, Abdullah G, Kim, Hoon, Mathew, Bijo

“…Due to the multifaceted pharmacological activities of chalcones, these scaffolds have been considered one of the most privileged frameworks in the drug…”
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A Comprehensive Review of the Docking Studies of Chalcone for the Development of Selective MAO-B Inhibitors by Krishna, Athulya, Kumar, Sunil, Sudevan, Sachithra Thazhathuveedu, Singh, Ashutosh Kumar, Pappachen, Leena K, Rangarajan, T M, Abdelgawad, Mohamed A, Mathew, Bijo

“…Monoamine oxidase B is a crucial therapeutic target for neurodegenerative disorders like Alzheimer's and Parkinson's since they assist in disintegrating…”
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A computational investigation of thymidylate synthase inhibitors through a combined approach of 3D-QSAR and pharmacophore modelling by Benny, Sonu, Rajappan Krishnendu, Prayaga, Kumar, Sunil, Bhaskar, Vaishnav, Manisha, Deepthi S., Abdelgawad, Mohamed A., Ghoneim, Mohammed M., Naguib, Ibrahim A., Pappachen, Leena. K., Mary Zachariah, Subin, Mathew, Bijo, TP, Aneesh

“…Thymidylate synthase (TS) is a crucial target of cancer drug discovery and is mainly involved in the De novo synthesis of the DNA precursor thymine. In the…”
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Inhibition of monoamine oxidases by benzimidazole chalcone derivatives by Krishna, Athulya, Lee, Jiseong, Kumar, Sunil, Sudevan, Sachithra Thazhathuveedu, Uniyal, Prerna, Pappachen, Leena K., Kim, Hoon, Mathew, Bijo

“…Ten benzimidazole chalcone derivatives were synthesized, and their monoamine oxidase (MAO) inhibitory activity was evaluated. Most compounds showed higher…”
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SNAP (Stop Now And Plan): Helping children improve their self-control and externalizing behavior problems by Augimeri, Leena K., Walsh, Margaret, Donato, Adam, Blackman, Andrea, Piquero, Alex R.

“…The Stop Now And Plan (SNAP®) model is designed to improve self-control. Extant research however, has not considered how the program targets self-control and…”
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Polypharmacy in children and adolescents initiating antipsychotic drug in 2008-2016: a nationwide register study by Varimo, Eveliina, Saastamoinen, Leena K., Rättö, Hanna, Aronen, Eeva T.

“…The use of antipsychotics in children and adolescents has increased rapidly. Little is known about psychotropic polypharmacy in children and adolescent…”
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Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach by Nair, Aathira Sujathan, Oh, Jong-Min, Koyiparambath, Vishal Payyalot, Kumar, Sunil, Sudevan, Sachithra Thazhathuveedu, Soremekun, Opeyemi, Soliman, Mahmoud E., Khames, Ahmed, Abdelgawad, Mohamed A., Pappachen, Leena K., Mathew, Bijo, Kim, Hoon

“…Halogens have been reported to play a major role in the inhibition of monoamine oxidase (MAO), relating to diverse cognitive functions of the central nervous…”
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Current Perspective of COVID-19 on Neurology: A Mechanistic Insight by Kumar, Rajesh, Harilal, Seetha, M, Sabitha, Pappachan, Leena K, P R, Roshni, Mathew, Bijo

“…SARS-CoV-2, the novel coronavirus and the causative organism of the Covid-19 pandemic wreaked havoc worldwide producing asymptomatic to symptomatic cases…”
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