Search Results - "Leembruggen, Anita J. L."
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Colonic dilation and altered ex vivo gastrointestinal motility in the neuroligin‐3 knockout mouse
Published in Autism research (01-05-2020)“…Gastrointestinal (GI) dysfunction is commonly reported by people diagnosed with autism spectrum disorder (ASD; autism) but the cause is unknown. Mutations in…”
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Group I Metabotropic Glutamate Receptors Modulate Motility and Enteric Neural Activity in the Mouse Colon
Published in Biomolecules (Basel, Switzerland) (09-01-2023)“…Glutamate is the major excitatory neurotransmitter in the central nervous system, and there is evidence that Group-I metabotropic glutamate receptors (mGlu1…”
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Spatiotemporal Mapping Reveals Regional Gastrointestinal Dysfunction in mdx Dystrophic Mice Ameliorated by Oral L-arginine Supplementation
Published in Journal of neurogastroenterology and motility (01-01-2020)“…Patients with Duchenne muscular dystrophy exhibit significant, ongoing impairments in gastrointestinal (GI) function likely resulting from dysregulated nitric…”
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The enteric nervous system undergoes significant chemical and synaptic maturation during adolescence in mice
Published in Developmental biology (01-02-2020)“…Adolescence is a critical period of development. It is very likely that there is significant maturation of the enteric nervous system (ENS) of the gut during…”
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scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3
Published in Cellular and molecular gastroenterology and hepatology (01-01-2021)“…Bowel function requires coordinated activity of diverse enteric neuron subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate…”
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Circadian Control of Gastrointestinal Motility
Published in Advances in experimental medicine and biology (01-01-2022)“…With the earth's 24-h rotation cycle, physiological function fluctuates in both diurnal and nocturnal animals, thereby ensuring optimal functioning of the…”
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