Search Results - "Leelarathna, Lalantha"

COVID-19: Impact of and on Diabetes by Schofield, Jonathan, Leelarathna, Lalantha, Thabit, Hood

“…Diabetes has been identified as a pre-existing health condition linked with worse outcomes following coronavirus disease 2019 infection. Here we explore the…”
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Home Use of an Artificial Beta Cell in Type 1 Diabetes by Thabit, Hood, Tauschmann, Martin, Allen, Janet M, Leelarathna, Lalantha, Hartnell, Sara, Wilinska, Malgorzata E, Acerini, Carlo L, Dellweg, Sibylle, Benesch, Carsten, Heinemann, Lutz, Mader, Julia K, Holzer, Manuel, Kojzar, Harald, Exall, Jane, Yong, James, Pichierri, Jennifer, Barnard, Katharine D, Kollman, Craig, Cheng, Peiyao, Hindmarsh, Peter C, Campbell, Fiona M, Arnolds, Sabine, Pieber, Thomas R, Evans, Mark L, Dunger, David B, Hovorka, Roman

“…In two randomized trials conducted under home conditions, investigators compared closed-loop insulin delivery with sensor-augmented pump therapy in adults and…”
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Impact of COVID-19 lockdown on flash and real-time glucose sensor users with type 1 diabetes in England by Prabhu Navis, Joshi, Leelarathna, Lalantha, Mubita, Womba, Urwin, Andrea, Rutter, Martin K., Schofield, Jonathan, Thabit, Hood

“…Aims People with type 1 diabetes (T1D) face the daily task of implementing self-management strategies to achieve their glycaemic goals. The UK COVID-19…”
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Accuracy of flash glucose monitoring and continuous glucose monitoring technologies: Implications for clinical practice by Ajjan, Ramzi A, Cummings, Michael H, Jennings, Peter, Leelarathna, Lalantha, Rayman, Gerry, Wilmot, Emma G

“…Continuous glucose monitoring and flash glucose monitoring technologies measure glucose in the interstitial fluid and are increasingly used in diabetes care…”
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Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data by Leelarathna, Lalantha, Beck, Roy W, Bergenstal, Richard M, Thabit, Hood, Hovorka, Roman

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Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial by Leelarathna, Lalantha, English, Shane W, Thabit, Hood, Caldwell, Karen, Allen, Janet M, Kumareswaran, Kavita, Wilinska, Malgorzata E, Nodale, Marianna, Mangat, Jasdip, Evans, Mark L, Burnstein, Rowan, Hovorka, Roman

“…Closed-loop (CL) systems modulate insulin delivery according to glucose levels without nurse input. In a prospective randomized controlled trial, we evaluated…”
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Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study by Thabit, Hood, MD, Lubina-Solomon, Alexandra, PhD, Stadler, Marietta, PhD, Leelarathna, Lalantha, PhD, Walkinshaw, Emma, MRCP, Pernet, Andrew, RN, Allen, Janet M, RN, Iqbal, Ahmed, MRCP, Choudhary, Pratik, MD, Kumareswaran, Kavita, PhD, Nodale, Marianna, MSc, Nisbet, Chloe, BMedSci, Wilinska, Malgorzata E, PhD, Barnard, Katharine D, PhD, Dunger, David B, Prof, Heller, Simon R, Prof, Amiel, Stephanie A, Prof, Evans, Mark L, FRCP, Hovorka, Roman, Dr

“…Summary Background Closed-loop insulin delivery is a promising option to improve glycaemic control and reduce the risk of hypoglycaemia. We aimed to assess…”
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The value of fast-acting insulin aspart compared with insulin aspart for patients with diabetes mellitus treated with bolus insulin from a UK health care system perspective by Leelarathna, Lalantha, Ashley, Donna, Fidler, Carrie, Parekh, Witesh

“…Background: Fast-acting insulin aspart is a new formulation of the rapid-acting insulin analogue insulin aspart and represents an advancement over current…”
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Glucose management for exercise using continuous glucose monitoring: should sex and prandial state be additional considerations? Reply to Yardley JE and Sigal RJ [letter] by Moser, Othmar, Riddell, Michael C., Eckstein, Max L., Adolfsson, Peter, Rabasa-Lhoret, Rémi, van den Boom, Louisa, Gillard, Pieter, Nørgaard, Kirsten, Oliver, Nick S., Zaharieva, Dessi P., Battelino, Tadej, de Beaufort, Carine, Bergenstal, Richard M., Buckingham, Bruce, Cengiz, Eda, Deeb, Asma, Heise, Tim, Heller, Simon, Kowalski, Aaron J., Leelarathna, Lalantha, Mathieu, Chantal, Stettler, Christoph, Tauschmann, Martin, Thabit, Hood, Wilmot, Emma G., Sourij, Harald, Smart, Carmel E., Jacobs, Peter G., Bracken, Richard M., Mader, Julia K.

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Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes-Findings from a Large UK Centre by Lee, Kyuhan, Gunasinghe, Shakthi, Chapman, Alyson, Findlow, Lynne A, Hyland, Jody, Ohol, Sheetal, Urwin, Andrea, Rutter, Martin K, Schofield, Jonathan, Thabit, Hood, Leelarathna, Lalantha

“…Flash glucose monitoring (FGM) and real-time continuous glucose monitoring (RT-CGM) are increasingly used in clinical practice, with improvements in HbA1c and…”
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Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes by Thabit, Hood, Dr, Elleri, Daniela, PhD, Leelarathna, Lalantha, PhD, Allen, Janet, RN, Lubina-Solomon, Alexandra, PhD, Stadler, Marietta, PhD, Walkinshaw, Emma, MD, Iqbal, Ahmed, MD, Choudhary, Pratik, MD, Wilinska, Malgorzata, PhD, Barnard, Katharine, PhD, Heller, Simon, Prof, Amiel, Stephanie, Prof, Evans, Mark, FRCP, Dunger, David, Prof, Hovorka, Roman, PhD

“…Abstract Background The closed-loop system (artificial pancreas) delivers insulin in a glucose-responsive manner by the use of a control algorithm that…”
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Insulin Delivery Hardware: Pumps and Pens by Lal, Rayhan, Leelarathna, Lalantha

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Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial) by Little, Stuart, Chadwick, Thomas, Choudhary, Pratik, Brennand, Cath, Stickland, Julia, Barendse, Shalleen, Olateju, Tolulope, Leelarathna, Lalantha, Walkinshaw, Emma, Tan, Horng K, Marshall, Sally M, Thomas, Reena M, Heller, Simon, Evans, Mark, Kerr, David, Flanagan, Daniel, Speight, Jane, Shaw, James Am

“…Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of…”
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Basal insulin delivery reduction for exercise in type 1 diabetes: finding the sweet spot by Thabit, Hood, Leelarathna, Lalantha

“…Exercise poses significant challenges to glucose management in type 1 diabetes. In spite of careful planning and manipulation of subcutaneous insulin…”
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Insulin Pumps by Lal, Rayhan, Leelarathna, Lalantha

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THE MINIMED ™ 670G HYBRID AUTOMATED INSULIN DELIVERY SYSTEM: SETTING THE RIGHT EXPECTATIONS by Leelarathna, Lalantha, Thabit, Hood

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Beware the pitfalls of time below range by Thabit, Hood, Schofield, Jonathan, Leelarathna, Lalantha

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Automated insulin dosing systems: Advances after a century of insulin by Thabit, Hood, Lal, Rayhan, Leelarathna, Lalantha

“…The daily complexities of insulin therapy and glucose variability in type 1 diabetes still pose significant challenges, despite advancements in modern insulin…”
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Hybrid closed‐loop therapy: Where are we in 2021? by Leelarathna, Lalantha, Choudhary, Pratik, Wilmot, Emma G., Lumb, Alistair, Street, Tim, Kar, Partha, Ng, Sze M.

“…Hybrid closed‐loop systems are characterized by the coexistence of algorithm‐driven automated insulin delivery combined with manual mealtime boluses. Used…”
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Use of Factory-Calibrated Real-time Continuous Glucose Monitoring Improves Time in Target and HbA1c in a Multiethnic Cohort of Adolescents and Young Adults With Type 1 Diabetes: The MILLENNIALS Study by Thabit, Hood, Prabhu, Joshi Navis, Mubita, Womba, Fullwood, Catherine, Azmi, Shazli, Urwin, Andrea, Doughty, Ian, Leelarathna, Lalantha

“…OBJECTIVE International type 1 diabetes registries have shown that HbA1c levels are highest in young people with type 1 diabetes; however, improving their…”
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