Search Results - "Leed, Alison J."

Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides by Reidenbach, Andrew G, Minikel, Eric Vallabh, Zhao, Hien T, Guzman, Stacy G, Leed, Alison J, Mesleh, Michael F, Kordasiewicz, Holly B, Schreiber, Stuart L, Vallabh, Sonia M

“…Antisense oligonucleotides (ASOs) designed to lower prion protein (PrP) expression in the brain through RNase H1-mediated degradation of PrP RNA are in…”
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Multimodal small-molecule screening for human prion protein binders by Reidenbach, Andrew G., Mesleh, Michael F., Casalena, Dominick, Vallabh, Sonia M., Dahlin, Jayme L., Leed, Alison J., Chan, Alix I., Usanov, Dmitry L., Yehl, Jenna B., Lemke, Christopher T., Campbell, Arthur J., Shah, Rishi N., Shrestha, Om K., Sacher, Joshua R., Rangel, Victor L., Moroco, Jamie A., Sathappa, Murugappan, Nonato, Maria Cristina, Nguyen, Kong T., Wright, S. Kirk, Liu, David R., Wagner, Florence F., Kaushik, Virendar K., Auld, Douglas S., Schreiber, Stuart L., Minikel, Eric Vallabh

“…Prion disease is a rapidly progressive neurodegenerative disorder caused by misfolding and aggregation of the prion protein (PrP), and there are currently no…”
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