Search Results - "Lee-Wen Chen"

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  1. 1

    The varicella-zoster virus ORF16 protein promotes both the nuclear transport and the protein abundance of the viral DNA polymerase subunit ORF28 by Lin, Huang-Shen, Li, Cheng-Han, Chen, Lee-Wen, Wang, Shie-Shan, Chen, Li-Yu, Hung, Chien-Hui, Lin, Chun-Liang, Chang, Pey-Jium

    Published in Virus research (01-07-2024)
    “…•Several VZV-encoded replication enzymes per se are localized in the cytoplasm.•The nuclear import of VZV ORF28 can be mediated by ORF16.•ORF16 can enhance the…”
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  2. 2

    Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein Represses Cellular MDM2 Expression via Suppressing the Sp1- and p53-Mediated Transactivation by Lin, Chia-I, Wang, Shie-Shan, Hung, Chien-Hui, Chang, Pey-Jium, Chen, Lee-Wen

    “…The Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded ORF50 protein is a potent transcriptional activator essential for triggering KSHV lytic…”
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  3. 3

    The Epstein-Barr Virus Lytic Protein BMLF1 Induces Upregulation of GRP78 Expression through ATF6 Activation by Chen, Lee-Wen, Wang, Shie-Shan, Hung, Chien-Hui, Hung, Ya-Hui, Lin, Chun-Liang, Chang, Pey-Jium

    “…The unfolded protein response (UPR) is an intracellular signaling pathway essential for alleviating the endoplasmic reticulum (ER) stress. To support the…”
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  4. 4

    Comparing Artificial Intelligence-Enabled Electrocardiogram Models in Identifying Left Atrium Enlargement and Long-term Cardiovascular Risk by Chou, Chung-Chuan, Liu, Zhi-Yong, Chang, Po-Cheng, Liu, Hao-Tien, Wo, Hung-Ta, Lee, Wen-Chen, Wang, Chun-Chieh, Chen, Jung-Sheng, Kuo, Chang-Fu, Wen, Ming-Shien

    Published in Canadian journal of cardiology (01-04-2024)
    “…The role of P-wave in identifying left atrial enlargement (LAE) with the use of artificial intelligence (AI)–enabled electrocardiography (ECG) models is…”
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  5. 5

    Characterization of Human Norovirus Nonstructural Protein NS1.2 Involved in the Induction of the Filamentous Endoplasmic Reticulum, Enlarged Lipid Droplets, LC3 Recruitment, and Interaction with NTPase and NS4 by Hung, Chien-Hui, Yen, Ju-Bei, Chang, Pey-Jium, Chen, Lee-Wen, Huang, Tsung-Yu, Tsai, Wan-Ju, Tsai, Yu-Chin

    Published in Viruses (01-03-2023)
    “…Human noroviruses (HuNVs) are the leading cause of gastroenteritis worldwide. NS1.2 is critical for HuNV pathogenesis, but the function is still unclear. The…”
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  6. 6

    Subcellular Localization and Functional Characterization of GII.4 Norovirus-Encoded NTPase by Yen, Ju-Bei, Wei, Ling-Huei, Chen, Lee-Wen, Chen, Li-Yu, Hung, Chien-Hui, Wang, Shie-Shan, Chang, Pey-Jium

    Published in Journal of virology (01-03-2018)
    “…The genotype II.4 (GII.4) variants of human noroviruses (HuNVs) are recognized as the major agent of global gastroenteritis outbreaks. Due to the lack of an…”
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  7. 7

    Identification of Location Specific Feature Points in a Cardiac Cycle Using a Novel Seismocardiogram Spectrum System by Lin, Wen-Yen, Tsai, Tsai-Hsuan, Lee, Ming-Yih, Chou, Wen-Cheng, Chang, Po-Cheng, Chou, Chung-Chuan, Wen, Ming-Shien, Ho, Ming-Yun, Lee, Wen-Chen, Hsieh, Ming-Jer, Lin, Chung-Chih

    “…Seismocardiogram (SCG) or mechanocardiography is a noninvasive cardiac diagnostic method; however, previous studies used only a single sensor to detect cardiac…”
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  8. 8

    Regulation of autophagic activation by Rta of Epstein-Barr virus via the extracellular signal-regulated kinase pathway by Hung, Chien-Hui, Chen, Lee-Wen, Wang, Wen-Hung, Chang, Pey-Jium, Chiu, Ya-Fang, Hung, Chen-Chia, Lin, Ying-Ju, Liou, Jieh-Yuan, Tsai, Wan-Ju, Hung, Chia-Ling, Liu, Shih-Tung

    Published in Journal of virology (01-10-2014)
    “…Autophagy is an intracellular degradation pathway that provides a host defense mechanism against intracellular pathogens. However, many viruses exploit this…”
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  9. 9

    Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus by Chang, Pey-Jium, Chen, Lee-Wen, Chen, Li-Yu, Hung, Chien-Hui, Shih, Ying-Ju, Wang, Shie-Shan

    Published in Journal of virology (01-10-2017)
    “…The switch of Kaposi's sarcoma-associated herpesvirus (KSHV) from latency to lytic replication is a key event for viral dissemination and pathogenesis…”
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  10. 10

    Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2 by Chang, Tzu-Hsuan, Wang, Shie-Shan, Chen, Lee-Wen, Shih, Ying-Ju, Chang, Li-Kwan, Liu, Shih-Tung, Chang, Pey-Jium

    Published in PLoS pathogens (01-10-2016)
    “…The switch between latency and the lytic cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50…”
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  11. 11

    Interaction Between BGLF2 and BBLF1 Is Required for the Efficient Production of Infectious Epstein-Barr Virus Particles by Hung, Chien-Hui, Chiu, Ya-Fang, Wang, Wen-Hung, Chen, Lee-Wen, Chang, Pey-Jium, Huang, Tsung-Yu, Lin, Ying-Ju, Tsai, Wan-Ju, Yang, Chia-Ching

    Published in Frontiers in microbiology (24-01-2020)
    “…BGLF2 is a tegument protein of the Epstein-Barr virus (EBV). This study finds that BGLF2 is expressed in the late stage of the EBV lytic cycle. Microscopic…”
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  12. 12

    Interaction and assembly of the DNA replication core proteins of Kaposi's sarcoma-associated herpesvirus by Chen, Lee-Wen, Wang, Shie-Shan, Chen, Li-Yu, Huang, Hsiao-Yun, He, Si-Min, Hung, Chien-Hui, Lin, Chun-Liang, Chang, Pey-Jium

    Published in Microbiology spectrum (12-12-2023)
    “…Eukaryotic DNA replication is a highly regulated process that requires multiple replication enzymes assembled onto DNA replication origins. Due to the…”
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  13. 13

    The rheology and extrusion processing performance of wood/melamine composites by Englund, Karl, Chen, Lee-Wen

    Published in Journal of applied polymer science (05-02-2014)
    “…ABSTRACT A modified melamine resin that exhibits both thermoplastic and thermoset behaviors was used as a matrix for wood plastic composites (WPCs). The…”
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  14. 14

    Brood success of sex-role-reversed pheasant-tailed jacanas: the effects of social polyandry, seasonality, and male mating order by Lee, Ya-Fu, Kuo, Yen-Min, Chuang, Bing-Yuan, Hsu, Hui-Ching, Huang, Yi-Jun, Su, Yu-Chen, Lee, Wen-Chen

    Published in Zoological letters (30-04-2024)
    “…Multiple mating by avian females may increase hatching and overall brood success; however, reproductive effort and parental investment are costly, and females…”
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  15. 15

    The N-terminal propeptide of type III procollagen in patients with acute coronary syndrome: a link between left ventricular end-diastolic pressure and cardiovascular events by Lee, Cheng-Hung, Lee, Wen-Chen, Chang, Shang-Hung, Wen, Ming-Shien, Hung, Kuo-Chun

    Published in PloS one (05-01-2015)
    “…Despite the usefulness of N-terminal propeptide of type III procollagen (PIIINP) in detecting enhanced collagen turnover in patients with congestive heart…”
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  16. 16

    Efficacy of portable sleep monitoring device in diagnosing central sleep apnea in patients with congestive heart failure by Tung, Pi-Hung, Hsieh, Meng-Jer, Chuang, Li-Pang, Lin, Shih-Wei, Hung, Kuo-Chun, Lu, Cheng-Hui, Lee, Wen-Chen, Hu, Han-Chung, Wen, Ming-Shien, Chen, Ning-Hung

    Published in Frontiers in neurology (21-12-2022)
    “…Central sleep apnea (CSA) is a common and serious comorbidity mainly occurring in patients with heart failure (HF), which tends to be underdiagnosed and has…”
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  17. 17

    Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein by Yen, Ju-Bei, Chen, Lee-Wen, Wei, Ling-Huei, Hung, Chien-Hui, Wang, Shie-Shan, Lin, Chun-Liang, Chang, Pey-Jium

    Published in Microbiology spectrum (03-09-2021)
    “…The human norovirus (HuNV)-encoded nucleoside-triphosphatase (NTPase) is a multifunctional protein critically involved in viral replication and pathogenesis…”
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  18. 18

    Sex Role Reversal and High Frequency of Social Polyandry in the Pheasant-Tailed Jacana (Hydrophasianus chirurgus) by Fresneau, Nolwenn, Lee, Ya-Fu, Lee, Wen-Chen, Kosztolányi, András, Székely, Tamás, Liker, András

    Published in Frontiers in ecology and evolution (03-11-2021)
    “…In a few species, males invest more than females in parental care while the females invest in mating competition and producing multiple broods for several…”
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  19. 19

    Caspase-Mediated Cleavage of the Transcription Factor Sp3: Possible Relevance to Cancer and the Lytic Cycle of Kaposi's Sarcoma-Associated Herpesvirus by Chen, Li-Yu, Chen, Lee-Wen, Hung, Chien-Hui, Lin, Chun-Liang, Wang, Shie-Shan, Chang, Pey-Jium

    Published in Microbiology spectrum (23-02-2022)
    “…The open reading frame 50 (ORF50) protein of Kaposi's sarcoma-associated herpesvirus (KSHV) is the master regulator essential for initiating the viral lytic…”
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  20. 20

    Relationship between Sugar Intake and Obesity among School-Age Children in Kaohsiung, Taiwan by LIN, Pei-Ying, LIN, Fang-Yu, CHEN, Ting-Chun, CHEN, Wen-Lee, DOONG, Jia-Yau, SHIKANAI, Saiko, SARUKURA, Nobuko, YAMAMOTO, Shigeru

    “…In recent years, the prevalence and problem of overweight and obesity in Taiwanese children have increased. There are many reports that the excessive intake of…”
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