Search Results - "Lee Gyu Seong"
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Four‐fold Channel‐Nicked Human Ferritin Nanocages for Active Drug Loading and pH‐Responsive Drug Release
Published in Angewandte Chemie International Edition (05-03-2018)“…Human ferritins are emerging platforms for non‐toxic protein‐based drug delivery, owing to their intrinsic or acquirable targeting abilities to cancer cells…”
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Moth pheromone‐selective projection neurons with cell bodies in the antennal lobe lateral cluster exhibit diverse morphological and neurophysiological characteristics
Published in Journal of comparative neurology (1911) (15-06-2019)“…Olfactory projection neurons convey information from the insect antennal lobe (AL) to higher brain centers. Previous reports have demonstrated that…”
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Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex
Published in Nature communications (30-07-2022)“…Insulin-like growth factors (IGFs) have pleiotropic roles in embryonic and postnatal growth and differentiation. Most serum IGFs are bound in a ternary complex…”
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Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore
Published in Nature communications (04-04-2023)“…In drug discovery, efficient screening of protein-drug interactions (PDIs) is hampered by the limitations of current biophysical approaches. Here, we develop a…”
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Functionally antagonistic polyelectrolyte for electro-ionic soft actuator
Published in Nature communications (10-01-2024)“…Electro-active ionic soft actuators have been intensively investigated as an artificial muscle for soft robotics due to their large bending deformations at low…”
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ClpL is a functionally active tetradecameric AAA+ chaperone, distinct from hexameric/dodecameric ones
Published in The FASEB journal (01-11-2020)“…AAA+ (ATPases associated with diverse cellular activities) chaperones are involved in a plethora of cellular activities to ensure protein homeostasis. The…”
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Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion
Published in Nature communications (14-11-2014)“…Synaptic adhesion molecules orchestrate synaptogenesis. The presynaptic leukocyte common antigen-related receptor protein tyrosine phosphatases (LAR-RPTPs)…”
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VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages
Published in PLoS pathogens (01-12-2012)“…Upon phagocytosis, Legionella pneumophila translocates numerous effector proteins into host cells to perturb cellular metabolism and immunity, ultimately…”
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SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
Published in Nature communications (02-08-2016)“…Synaptic adhesion molecules regulate various aspects of synapse development, function and plasticity. These functions mainly involve trans -synaptic…”
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Transplant Antennae and Host Brain Interact to Shape Odor Perceptual Space in Male Moths
Published in PloS one (27-01-2016)“…Behavioral responses to odors rely first upon their accurate detection by peripheral sensory organs followed by subsequent processing within the brain's…”
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Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR-mediated bacterial immunity
Published in Proteins, structure, function, and bioinformatics (01-11-2012)“…Many prokaryotic organisms acquire immunity against foreign genetic material by incorporating a short segment of foreign DNA called spacer into chromosomal…”
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Identification of a Highly Conserved Hypothetical Protein TON_0340 as a Probable Manganese-Dependent Phosphatase
Published in PloS one (01-12-2016)“…A hypothetical protein TON_0340 of a Thermococcus species is a protein conserved in a variety of organisms including human. Herein, we present four different…”
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Characterization of passive microfluidic mixer with a three-dimensional zig-zag channel for cryo-EM sampling
Published in Chemical engineering science (05-11-2023)“…•Investigation of microfluidic passive mixer geometries for improved mixing efficiency.•Computational estimation and experimental results for assessing the…”
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15
SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development
Published in Scientific reports (26-05-2016)“…Synaptogenic adhesion molecules play critical roles in synapse formation. SALM5/Lrfn5, a SALM/Lrfn family adhesion molecule implicated in autism spectrum…”
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Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex
Published in Nucleic acids research (06-04-2020)“…Abstract Monoubiquitination of the Fanconi anemia complementation group D2 (FANCD2) protein by the FA core ubiquitin ligase complex is the central event in the…”
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Environmental disinfection with photocatalyst as an adjunctive measure to control transmission of methicillin-resistant Staphylococcus aureus: a prospective cohort study in a high-incidence setting
Published in BMC infectious diseases (03-12-2018)“…Environmental disinfection with continuously antimicrobial surfaces could offer superior control of surface bioburden. We sought to decide the efficacy of…”
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Designing 3D Anode Based on Pore‐Size‐Dependent Li Deposition Behavior for Reversible Li‐Free All‐Solid‐State Batteries
Published in Advanced science (01-10-2022)“…Li‐free all‐solid‐state batteries can achieve high energy density and safety. However, separation of the current collector/solid electrolyte interface during…”
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Antennal lobe projection destinations of Helicoverpa zea male olfactory receptor neurons responsive to heliothine sex pheromone components
Published in Journal of Comparative Physiology (01-04-2006)“…We used single sensillum recordings to define male Helicoverpa zea olfactory receptor neuron physiology followed by cobalt staining to trace the axons to…”
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Four‐fold Channel‐Nicked Human Ferritin Nanocages for Active Drug Loading and pH‐Responsive Drug Release
Published in Angewandte Chemie (05-03-2018)“…Human ferritins are emerging platforms for non‐toxic protein‐based drug delivery, owing to their intrinsic or acquirable targeting abilities to cancer cells…”
Get full text
Journal Article