Search Results - "Lee, john"
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Perspectives on Bioluminescence Mechanisms
Published in Photochemistry and photobiology (01-03-2017)“…The molecular mechanisms of the bioluminescence systems of the firefly, bacteria and those utilizing imidazopyrazinone luciferins such as coelenterazine are…”
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2
The second window ICG technique demonstrates a broad plateau period for near infrared fluorescence tumor contrast in glioblastoma
Published in PloS one (24-07-2017)“…Fluorescence-guided surgery has emerged as a powerful tool to detect, localize and resect tumors in the operative setting. Our laboratory has pioneered a novel…”
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3
Global reach of ageism on older persons' health: A systematic review
Published in PloS one (01-01-2020)“…Although there is anecdotal evidence of ageism occurring at both the structural level (in which societal institutions reinforce systematic bias against older…”
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Intraoperative Near-Infrared Optical Imaging Can Localize Gadolinium-Enhancing Gliomas During Surgery
Published in Neurosurgery (01-12-2016)“…Abstract BACKGROUND: Although real-time localization of gliomas has improved with intraoperative image guidance systems, these tools are limited by brain…”
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5
Trusting Automation: Designing for Responsivity and Resilience
Published in Human factors (01-02-2023)“…Objective This paper reviews recent articles related to human trust in automation to guide research and design for increasingly capable automation in complex…”
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Optical Principles of Fluorescence-Guided Brain Tumor Surgery: A Practical Primer for the Neurosurgeon
Published in Neurosurgery (01-09-2019)“…Fluorescence-guided surgery is a rapidly growing field that has produced some of the most important innovations in surgical oncology in the past decade. These…”
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Trends in racial and ethnic discrimination in hiring in six Western countries
Published in Proceedings of the National Academy of Sciences - PNAS (07-02-2023)“…We examine trends in racial and ethnic discrimination in hiring in six European and North American countries: Canada, France, Germany, Great Britain, the…”
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Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Published in Nature (London) (01-08-2019)“…Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that change over the course…”
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Associations between multimorbidity, healthcare utilisation and health status: evidence from 16 European countries
Published in Age and ageing (01-05-2016)“…with ageing populations and increasing exposure to risk factors for chronic diseases, the prevalence of chronic disease multimorbidity is rising globally…”
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10
Gut microbiota and tacrolimus dosing in kidney transplantation
Published in PloS one (27-03-2015)“…Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient…”
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11
Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes
Published in Neuron (Cambridge, Mass.) (21-01-2015)“…Huntington's disease (HD) is caused by a polyglutamine tract expansion in huntingtin (HTT). Despite HTTs ubiquitous expression, there is early and robust…”
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Impact of Noncommunicable Disease Multimorbidity on Healthcare Utilisation and Out-Of-Pocket Expenditures in Middle-Income Countries: Cross Sectional Analysis
Published in PloS one (08-07-2015)“…The burden of non-communicable disease (NCDs) has grown rapidly in low- and middle-income countries (LMICs), where populations are ageing, with rising…”
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Segmentation of positron emission tomography images: Some recommendations for target delineation in radiation oncology
Published in Radiotherapy and oncology (01-09-2010)“…Abstract Positron emission tomography can be used in radiation oncology for the delineation of target volumes in the treatment planning stage. Numerous…”
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14
Imaging and quantifying ganglion cells and other transparent neurons in the living human retina
Published in Proceedings of the National Academy of Sciences - PNAS (28-11-2017)“…Ganglion cells (GCs) are fundamental to retinal neural circuitry, processing photoreceptor signals for transmission to the brain via their axons. However, much…”
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15
Exploring Trust in Self-Driving Vehicles Through Text Analysis
Published in Human factors (01-03-2020)“…Objective This study examined attitudes toward self-driving vehicles and the factors motivating those attitudes. Background Self-driving vehicles represent…”
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Evidence from Field Experiments in Hiring Shows Substantial Additional Racial Discrimination after the Callback
Published in Social forces (01-12-2020)“…Abstract Field experiments using fictitious applications have become an increasingly important method for assessing hiring discrimination. Most field…”
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Complement dysregulation in the central nervous system during development and disease
Published in Seminars in immunology (01-10-2019)“…•Complement proteins play essential roles in brain development.•Complement signalling can both protect against and aggravate neurological disease.•Complement…”
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The Complement Receptor C5aR2: A Powerful Modulator of Innate and Adaptive Immunity
Published in The Journal of immunology (1950) (15-06-2019)“…Complement activation generates the core effector protein C5a, a potent immune molecule that is linked to multiple inflammatory diseases. Two C5a receptors,…”
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Variable Age at Onset in AOPEP‐Associated Dystonia
Published in Movement disorders (01-12-2023)Get full text
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Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas
Published in Nature genetics (01-02-2014)“…Sandro Santagata, Gad Getz and colleagues report the discovery of a recurrent mutation in the oncogene BRAF in papillary craniopharyngiomas that does not occur…”
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