Search Results - "Lee, Yun S"

The vaginal microbiome during pregnancy and the postpartum period in a European population by MacIntyre, David A., Chandiramani, Manju, Lee, Yun S., Kindinger, Lindsay, Smith, Ann, Angelopoulos, Nicos, Lehne, Benjamin, Arulkumaran, Shankari, Brown, Richard, Teoh, Tiong Ghee, Holmes, Elaine, Nicoholson, Jeremy K., Marchesi, Julian R., Bennett, Phillip R.

“…The composition and structure of the pregnancy vaginal microbiome may influence susceptibility to adverse pregnancy outcomes. Studies on the pregnant vaginal…”
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Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin by Brown, Richard G, Marchesi, Julian R, Lee, Yun S, Smith, Ann, Lehne, Benjamin, Kindinger, Lindsay M, Terzidou, Vasso, Holmes, Elaine, Nicholson, Jeremy K, Bennett, Phillip R, MacIntyre, David A

“…Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is…”
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The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next? by Mitra, Anita, MacIntyre, David A, Marchesi, Julian R, Lee, Yun S, Bennett, Phillip R, Kyrgiou, Maria

“…The vaginal microbiota plays a significant role in health and disease of the female reproductive tract. Next-generation sequencing techniques based upon the…”
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The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk by Kindinger, Lindsay M, Bennett, Phillip R, Lee, Yun S, Marchesi, Julian R, Smith, Ann, Cacciatore, Stefano, Holmes, Elaine, Nicholson, Jeremy K, Teoh, T G, MacIntyre, David A

“…Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In…”
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Chromosomally normal miscarriage is associated with vaginal dysbiosis and local inflammation by Grewal, Karen, Lee, Yun S, Smith, Ann, Brosens, Jan J, Bourne, Tom, Al-Memar, Maya, Kundu, Samit, MacIntyre, David A, Bennett, Phillip R

“…Emerging evidence supports an association between vaginal microbiota composition and risk of miscarriage; however, the underlying mechanisms are poorly…”
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Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response by Chan, Denise, Bennett, Phillip R., Lee, Yun S., Kundu, Samit, Teoh, T. G., Adan, Malko, Ahmed, Saqa, Brown, Richard G., David, Anna L., Lewis, Holly V., Gimeno-Molina, Belen, Norman, Jane E., Stock, Sarah J., Terzidou, Vasso, Kropf, Pascale, Botto, Marina, MacIntyre, David A., Sykes, Lynne

“…There has been a surge in studies implicating a role of vaginal microbiota in spontaneous preterm birth (sPTB), but most are associative without mechanistic…”
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Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage by Kindinger, Lindsay M, MacIntyre, David A, Lee, Yun S, Marchesi, Julian R, Smith, Ann, McDonald, Julie A K, Terzidou, Vasso, Cook, Joanna R, Lees, Christoph, Israfil-Bayli, Fidan, Faiza, Yazmin, Toozs-Hobson, Philip, Slack, Mark, Cacciatore, Stefano, Holmes, Elaine, Nicholson, Jeremy K, Teoh, T G, Bennett, Phillip R

“…Preterm birth, the leading cause of death in children under 5 years, may be caused by inflammation triggered by ascending vaginal infection. About 2 million…”
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Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth by Pruski, Pamela, Correia, Gonçalo D. S., Lewis, Holly V., Capuccini, Katia, Inglese, Paolo, Chan, Denise, Brown, Richard G., Kindinger, Lindsay, Lee, Yun S., Smith, Ann, Marchesi, Julian, McDonald, Julie A. K., Cameron, Simon, Alexander-Hardiman, Kate, David, Anna L., Stock, Sarah J., Norman, Jane E., Terzidou, Vasso, Teoh, T. G., Sykes, Lynne, Bennett, Phillip R., Takats, Zoltan, MacIntyre, David A.

“…The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct…”
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Activator protein 1 is a key terminal mediator of inflammation‐induced preterm labor in mice by MacIntyre, David A., Lee, Yun S., Migale, Roberta, Herbert, Bronwen R., Waddington, Simon N., Peebles, Donald, Hagberg, Henrik, Johnson, Mark R., Bennett, Phillip R.

“…ABSTRACT Activation of uterine inflammatory pathways leads to preterm labor (PTL), associated with high rates of neonatal mortality and morbidity. The…”
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Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States by LEE, Yun S, KIM, Woo S, HOHNEN-BEHRENS, Cordula, GOSBY, Alison, KRAEGEN, Edward W, JAMES, David E, KIM, Jae B, KIM, Kang H, YOON, Myung J, CHO, Hye J, YUN SHEN, YE, Ji-Ming, LEE, Chul H, OH, Won K, KIM, Chul T

“…Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States Yun S…”
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The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia by Mitra, Anita, MacIntyre, David A, Paraskevaidi, Maria, Moscicki, Anna-Barbara, Mahajan, Vishakha, Smith, Ann, Lee, Yun S, Lyons, Deirdre, Paraskevaidis, Evangelos, Marchesi, Julian R, Bennett, Phillip R, Kyrgiou, Maria

“…Vaginal microbiota (VMB) composition is altered in women with cervical intra-epithelial neoplasia (CIN) compared to healthy controls and is associated with…”
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Comparison of vaginal microbiota sampling techniques: cytobrush versus swab by Mitra, Anita, MacIntyre, David A., Mahajan, Vishakha, Lee, Yun S., Smith, Ann, Marchesi, Julian R., Lyons, Deirdre, Bennett, Phillip R., Kyrgiou, Maria

“…Evidence suggests the vaginal microbiota (VM) may influence risk of persistent Human Papillomavirus (HPV) infection and cervical carcinogenesis. Established…”
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15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells by Rasheed, Zahirrah Bm, Lee, Yun S, Kim, Sung H, Teoh, Tg, MacIntyre, David A, Bennett, Phillip R, Sykes, Lynne

“…Prematurity is the leading cause of childhood death under the age of five. The aetiology of preterm birth is multifactorial; however, inflammation and…”
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Lactobacillus -Depleted Vaginal Microbiota in Pregnant Women Living With HIV-1 Infection Are Associated With Increased Local Inflammation and Preterm Birth by Short, Charlotte-Eve S, Brown, Richard G, Quinlan, Rachael, Lee, Yun S, Smith, Ann, Marchesi, Julian R, Shattock, Robin, Bennett, Phillip R, Taylor, Graham P, MacIntyre, David A

“…Pregnant women living with HIV-1 infection (PWLWH) have an elevated risk of preterm birth (PTB) of unknown aetiology, which remains after successful…”
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The association between obesity and weight loss after bariatric surgery on the vaginal microbiota by Raglan, Olivia, MacIntyre, David A, Mitra, Anita, Lee, Yun S, Smith, Ann, Assi, Nada, Nautiyal, Jaya, Purkayastha, Sanjay, Gunter, Marc J, Gabra, Hani, Marchesi, Julian R, Bennett, Phillip R, Kyrgiou, Maria

“…Obesity and vaginal microbiome (VMB) dysbiosis are each risk factors for adverse reproductive and oncological health outcomes in women. Here, we investigated…”
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Comparative analysis of vaginal microbiota sampling using menstrual cups and high vaginal swabs in pregnant women living with HIV-1 infection by Short, Charlotte-Eve S, Quinlan, Rachael, Lee, Yun S, Preda, Veronica G, Smith, Ann, Marchesi, Julian R, Shattock, Robin, Bennett, Phillip R, MacIntyre, David A, Taylor, Graham P

“…Menstrual cups (MCs) are increasingly used to collect cervicovaginal secretions to characterise vaginal mucosal immunology, in conjunction with high vaginal…”
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Differential Response of Gestational Tissues to TLR3 Viral Priming Prior to Exposure to Bacterial TLR2 and TLR2/6 Agonists by Rasheed, Zahirrah B M, Lee, Yun S, Kim, Sung H, Rai, Ranjit K, Ruano, Camino S M, Anucha, Eberechi, Sullivan, Mark H F, MacIntyre, David A, Bennett, Phillip R, Sykes, Lynne

“…Infection/inflammation is an important causal factor in spontaneous preterm birth (sPTB). Most mechanistic studies have concentrated on the role of bacteria,…”
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Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes by Lim, Sheri, MacIntyre, David A, Lee, Yun S, Khanjani, Shirin, Terzidou, Vasso, Teoh, T G, Bennett, Phillip R

“…Prior to the onset of human labour there is an increase in the synthesis of prostaglandins, cytokines and chemokines in the fetal membranes, particular the…”
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Persistence of IL‐2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis by Yu, Cheng‐Rong, Oh, Hyun‐Mee, Golestaneh, Nady, Amadi‐Obi, Ahjoku, S. Lee, Yun, Eseonu, Amarachi, Mahdi, Rashid M., Egwuagu, Charles E.

“…Compared with other T‐helper subsets, Th17 cell numbers are very low in human blood but become elevated in chronic inflammatory diseases. In this study, we…”
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Establishment of vaginal microbiota composition in early pregnancy and its association with subsequent preterm prelabor rupture of the fetal membranes by Brown, Richard G., Al-Memar, Maya, Marchesi, Julian R., Lee, Yun S, Smith, Ann, Chan, Denise, Lewis, Holly, Kindinger, Lindsay, Terzidou, Vasso, Bourne, Tom, Bennett, Phillip R., MacIntyre, David A.

“…Vaginal bacterial community composition influences pregnancy outcome. Preterm prelabor rupture of the fetal membranes (PPROM), which precedes 30% of all…”
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