Search Results - "Lee, Yun Haeng"

Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence by Kuk, Myeong Uk, Lee, Haneur, Song, Eun Seon, Lee, Yun Haeng, Park, Ji Yun, Jeong, Subin, Kwon, Hyung Wook, Byun, Youngjoo, Park, Sang Chul, Park, Joon Tae

“…Senescence is a phenomenon defined by alterations in cellular organelles and is the primary cause of aging and aging-related diseases. Recent studies have…”
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Identification of Cellular Isoschaftoside-Mediated Anti-Senescence Mechanism in RAC2 and LINC00294 by Lee, Yun Haeng, So, Byeong Hyeon, Lee, Kyeong Seon, Kuk, Myeong Uk, Park, Ji Ho, Yoon, Jee Hee, Lee, Yoo Jin, Kim, Du Yeol, Kim, Min Seon, Kwon, Hyung Wook, Byun, Youngjoo, Lee, Ki Yong, Park, Joon Tae

“…As cellular senescence, reactive oxygen species (ROS) accumulate excessively, causing cellular damage. Flavonoids derived from natural products are known for…”
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Senescence Rejuvenation through Reduction in Mitochondrial Reactive Oxygen Species Generation by Polygonum cuspidatum Extract: In Vitro Evidence by Yoon, Jee Hee, Kim, Ye Hyang, Jeong, Eun Young, Lee, Yun Haeng, Byun, Youngjoo, Shin, Song Seok, Park, Joon Tae

“…Oxidative stress caused by reactive oxygen species (ROS) is one of the major causes of senescence. Strategies to reduce ROS are known to be important factors…”
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Assessment of Various Toxicity Endpoints in Duckweed (Lemna minor) at the Physiological, Biochemical, and Molecular Levels as a Measure of Diuron Stress by Lee, Hojun, Depuydt, Stephen, Shin, Kisik, Choi, Soyeon, Kim, Geonhee, Lee, Yun Haeng, Park, Joon Tae, Han, Taejun, Park, Jihae

“…The common, broad-spectrum herbicide diuron poses some risks to the environment due to its long persistence and high toxicity. Therefore, the effective…”
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Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases by Lee, Yun Haeng, Kuk, Myeong Uk, So, Moon Kyoung, Song, Eun Seon, Lee, Haneur, Ahn, Soon Kil, Kwon, Hyung Wook, Park, Joon Tae, Park, Sang Chul

“…Mitochondria are one of the organelles undergoing rapid alteration during the senescence process. Senescent cells show an increase in mitochondrial size, which…”
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Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence by Lee, Yun Haeng, Park, Ji Yun, Lee, Haneur, Song, Eun Seon, Kuk, Myeong Uk, Joo, Junghyun, Oh, Sekyung, Kwon, Hyung Wook, Park, Joon Tae, Park, Sang Chul

“…Mitochondria are one of organelles that undergo significant changes associated with senescence. An increase in mitochondrial size is observed in senescent…”
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Rapid and Accurate Ecotoxicological Assessment of Heavy Metals Using Cyprinus carpio Cells by Lee, Yun Haeng, Kuk, Myeong Uk, Park, Ji Ho, Lee, Hojun, Lee, Haneur, So, Moon Kyoung, Yoon, Jee Hee, Lee, Yoo Jin, Kim, Duyeol, So, Byeonghyeon, Kim, Minseon, Park, Jihae, Han, Taejun, Park, Joon Tae

“…Heavy metals have serious negative effects on various aquatic organisms, and therefore rapid and accurate ecotoxicological assessments of heavy metals are…”
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Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial-Lysosomal Axis by Kuk, Myeong Uk, Lee, Yun Haeng, Kim, Jae Won, Hwang, Su Young, Park, Joon Tae, Park, Sang Chul

“…Lysosomal storage disease (LSD) is an inherited metabolic disorder caused by enzyme deficiency in lysosomes. Some treatments for LSD can slow progression, but…”
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Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3 by Kuk, Myeong Uk, Ga, Yun Ji, Kim, Ye Jin, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Lee, Yun Haeng, Ko, Gahyun, Kim, Jae Kwang, Yeh, Jung-Yong, Kwon, Hyung Wook, Byun, Youngjoo, Park, Joon Tae

“…Coxsackievirus B3 (CVB3) is a single-stranded RNA virus that belongs to the Enterovirus genus. CVB3 is a human pathogen associated with serious conditions such…”
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A novel hybrid promoter capable of continuously producing proteins in high yield by Lee, Haneur, Song, Eun Seon, Lee, Yun Haeng, Park, Ji Yun, Kuk, Myeong Uk, Kwon, Hyung Wook, Roh, Hyungmin, Park, Joon Tae

“…The establishment of cell lines with a high protein production is the most crucial objective in the field of biopharmaceuticals. To this end, efforts have been…”
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Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence by Lee, Yun Haeng, Choi, Doyoung, Jang, Geonhee, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Kuk, Myeong Uk, Joo, Junghyun, Ahn, Soon Kil, Byun, Youngjoo, Park, Joon Tae

“…Senescence is a distinct set of changes in the senescence-associated secretory phenotype (SASP) and leads to aging and age-related diseases. Here, we screened…”
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Polyporus ulleungus mycelia cultured in MEB medium produce metabolites with anticancer property by Lee, Yun Haeng, Kuk, Myeong Uk, So, Moon Kyoung, Park, Hyon Jin, Song, Eun Seon, Park, Jiho, Yoon, Jee Hee, Kwon, Hyung Wook, Choi, Jaehyuk, Park, Joon Tae

“…Cancer cells are characterized by apoptosis evasion and uncontrolled cell cycle progression. To combat these characteristics, efforts have been made to find…”
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ROSA26 BAC-based system enables continuous high-yield protein production by Kuk, Myeong Uk, So, Moon Kyoung, Park, Ji Ho, Yoon, Jee Hee, Lee, Yoo Jin, Kim, Duyeol, So, Byeonghyeon, Lee, Yun Haeng, Kim, Minseon, Byun, Youngjoo, Kwon, Hyung Wook, Park, Joon Tae

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ATM mediated-p53 signaling pathway forms a novel axis for senescence control by Hwang, Su Young, Kuk, Myeong Uk, Kim, Jae Won, Lee, Yun Haeng, Lee, Young-Sam, Choy, Hyon E., Park, Sang Chul, Park, Joon Tae

“…•ATM inhibition yields senescence amelioration through a p53-dependent manner.•The restorative effect was also afforded by direct p53 inhibition via a chemical…”
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Improvement of Tol2 Transposon System by Modification of Tol2 Transposase by Park, Ji Yun, Lee, Haneur, Song, Eun Seon, Lee, Yun Haeng, Kuk, Myeong Uk, Ko, Gahyun, Byun, Youngjoo, Kwon, Hyung Wook, Park, Joon Tae

“…Tol2 transposon-based vector platform has been developed as a useful strategy to improve protein yield. Tol2 transposase identifies inverted terminal repeats…”
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Chemical screening identifies the anticancer properties of Polyporous parvovarius by Lee, Yun Haeng, Kim, Minkyeong, Park, Hyon Jin, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Ko, Gahyun, Ahn, Soonkil, Kwon, Hyung Wook, Byun, Youngjoo, Kim, Changmu, Choi, Jaehyuk, Park, Joon Tae

“…One of the biggest obstacles in cancer treatment is the development of chemoresistance. To overcome this, attempts have been made to screen novel anticancer…”
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Improvement of Sleeping Beauty Transposon System Enabling Efficient and Stable Protein Production by Lee, Yun Haeng, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Kuk, Myeong Uk, Joo, Junghyun, Roh, Hyungmin, Park, Joon Tae

“…The most essential goal in the field of biopharmaceuticals is to develop cell lines with higher protein yields. To this goal, the Sleeping Beauty (SB)…”
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Establishment of a new promoter trapping vector using 2A peptide by Song, Eun Seon, Lee, Yun Haeng, So, Moon Kyoung, Kuk, Myeong Uk, Park, Ji Ho, Yoon, Jee Hee, Lee, Yoo Jin, Kim, Duyeol, So, Byeonghyeon, Byun, Youngjoo, Kwon, Hyung Wook, Park, Joon Tae

“…Promoter trapping is a powerful tool for discovering promoters and uses promoter trapping vectors. However, the traditional trapping vector allows expression…”
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Bacterial Artificial Chromosome-based Protein Expression Platform Using the Tol2 Transposon System by Kuk, Myeong Uk, Park, Ji Yun, Song, Eun Seon, Lee, Haneur, Lee, Yun Haeng, Joo, Junghyun, Kwon, Hyung Wook, Park, Joon Tae

“…Conventional vector systems, including plasmid-based vectors, are mainly used in mammalian cells for the production of biopharmaceuticals. Plasmid-based…”
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Chemical screening identifies the anticancer properties of Polyporous tuberaster by Song, Eun Seon, So, Moon Kyoung, Park, Hyon Jin, Lee, Haneur, Lee, Yun Haeng, Kuk, Myeong Uk, Park, Jiho, Kwon, Hyung Wook, Choi, Jaehyuk, Park, Joon Tae

“…Most conventional anticancer drugs cause resistance to chemotherapy, which has emerged as one of the major obstacles to cancer treatment. In order to address…”
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