Search Results - "Lee, Yukyeong"
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Generation of integration-free human induced pluripotent stem cells from a patient with sporadic Parkinson’s disease
Published in Stem cell research (01-06-2024)“…A human induced pluripotent stem cell (iPSC) line (KKUi002-A) was generated from a skin fibroblast of a 57-years-old (at sampling) male patient diagnosed with…”
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Effects of Laser Power on the Microstructure Evolution and Mechanical Properties of Ti–6Al–4V Alloy Manufactured by Direct Energy Deposition
Published in Metals and materials international (2022)“…Process optimization of additively manufactured Ti–6Al–4V alloy is an important aspect of the production of engineered, high-performance parts for the…”
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Homogeneity of XEN Cells Is Critical for Generation of Chemically Induced Pluripotent Stem Cells
Published in Molecules and cells (01-04-2023)“…In induced pluripotent stem cells (iPSCs), pluripotency is induced artificially by introducing the transcription factors , , , and . When a transgene is…”
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The role of microRNA-325-3p as a critical player in cell death in NSCs and astrocytes
Published in Frontiers in cell and developmental biology (16-01-2024)“…Neural stem cells (NSCs) are defined by their ability to self-renew and generate various cell types within the nervous system. Understanding the underlying…”
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Mechanical property of the shape memorable Ti–Zr–Nb–Sn alloy manufactured by in-situ alloying in directed energy deposition
Published in Journal of materials research and technology (01-01-2024)“…Ni-free β-type Ti alloys have been developed to manufacture high-strength, low-elastic-modulus, shape-memorable medical, and non-toxic components. Because the…”
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Enhancement of proliferation of human umbilical cord blood–derived CD34+ hematopoietic stem cells by a combination of hyper-interleukin-6 and small molecules
Published in Biochemistry and biophysics reports (01-03-2022)“…Umbilical cord blood (UCB) is an alternative source of allogeneic hematopoietic stem cells (HSCs) for transplantation to treat various hematological disorders…”
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Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system
Published in Stem cell research (01-10-2020)“…OCT4 and NANOG are core transcription factor genes in self-renewal, differentiation, and reprogramming. Here, we generated an OCT4-EGFP, NANOG-tdTomato dual…”
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Two-Step Generation of Oligodendrocyte Progenitor Cells From Mouse Fibroblasts for Spinal Cord Injury
Published in Frontiers in cellular neuroscience (25-07-2018)“…Oligodendrocyte progenitor cells (OPCs) are attracting attention as the ideal cell therapy for spinal cord injury (SCI). Recently, advanced reprogramming and…”
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Reprogramming of spermatogonial stem cells into pluripotent stem cells in the spheroidal state
Published in Animal cells and systems (02-11-2019)“…Spermatogonial stem cells (SSCs) are unipotent adult stem cells, capable of differentiating into sperm cells. SSCs can be cultured in vitro for a long time…”
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Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation
Published in International journal of stem cells (30-03-2019)“…Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been…”
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Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells without Microenvironment of Feeder Cells
Published in Molecules and cells (2018)“…Spermatogonial stem cells (SSCs) derived from mouse testis are unipotent in regard of spermatogenesis. Our previous study demonstrated that SSCs can be fully…”
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Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2024)“…Many Mendelian disorders, such as Huntington's disease (HD) and spinocerebellar ataxias, arise from expansions of CAG trinucleotide repeats. Despite the clear…”
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Plant‐derived human recombinant growth factors and serum albumin maintain stemness of human‐induced pluripotent stem cells
Published in Cell biology international (01-01-2022)“…Stem cells are an important therapeutic source for recovery and regeneration, as their ability of self‐renewal and differentiation offers an unlimited supply…”
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Transformation-induced plasticity in the heterogeneous microstructured Ti-Zr-Nb-Sn alloy via in-situ alloying with directed energy deposition
Published in Additive manufacturing (01-10-2022)“…Adjusting the phase transformation behavior in metallic alloys is important for controlling both the strengthening capability and the shape memory effect in a…”
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Inhibition of Class I Histone Deacetylase Enhances Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells
Published in International journal of stem cells (28-02-2023)“…Spermatogonial stem cells (SSCs) are the most primitive cells in spermatogenesis and are the only adult stem cells capable of passing on the genome of a given…”
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Metastable δ-ferrite and twinning-induced plasticity on the strain hardening behavior of directed energy deposition-processed 304L austenitic stainless steel
Published in Additive manufacturing (01-11-2021)“…Rapid melting and solidification cycles during laser-based additive manufacturing create non-equilibrium microstructures in stainless steels (SSs) including…”
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Multigenerational effects of maternal cigarette smoke exposure during pregnancy on sperm counts of F1 and F2 male offspring
Published in Reproductive toxicology (Elmsford, N.Y.) (01-06-2018)“…•Maternal cigarette smoke exposure caused low sperm counts of male offspring.•Seminiferous epithelium heights of male offspring were decreased in the exposed…”
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Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells without Microenvironment of Feeder Cells
Published in Molecules and cells (31-07-2018)“…Spermatogonial stem cells (SSCs) derived from mouse testis are unipotent in regard of spermatogenesis. Our previous study demonstrated that SSCs can be fully…”
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