Search Results - "Lee, Young Seung"

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness by Yue, Shuhua, Li, Junjie, Lee, Seung-Young, Lee, Hyeon Jeong, Shao, Tian, Song, Bing, Cheng, Liang, Masterson, Timothy A., Liu, Xiaoqi, Ratliff, Timothy L., Cheng, Ji-Xin

“…Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled by label-free Raman spectromicroscopy, we performed quantitative…”
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Quinic Acid‐Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins by Xu, Jun, Lee, Steve Seung‐Young, Seo, Howon, Pang, Liang, Jun, Yearin, Zhang, Ruo‐Yu, Zhang, Zhong‐Yin, Kim, Pilhan, Lee, Wooin, Kron, Stephen J., Yeo, Yoon

“…Current nanoparticle (NP) drug carriers mostly depend on the enhanced permeability and retention (EPR) effect for selective drug delivery to solid tumors…”
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Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles by Nam, Hae Yun, Kwon, Seok Min, Chung, Hyunjin, Lee, Seung-Young, Kwon, Seung-Hae, Jeon, Hyesung, Kim, Yoonkyung, Park, Jae Hyung, Kim, Joon, Her, Songwook, Oh, Yu-Kyoung, Kwon, Ick Chan, Kim, Kwangmeyung, Jeong, Seo Young

“…Polymeric nanoparticle-based carriers are promising agents for the targeted delivery of therapeutics to the intracellular site of action. To optimize the…”
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Effects of the treatment parameters on the efficacy of the inactivation of Salmonella contaminating boiled chicken breast by in-package atmospheric cold plasma treatment by Roh, Si Hyeon, Lee, Seung Young, Park, Hyeon Hwa, Lee, Eun Song, Min, Sea C.

“…The effects of surface coating, microbial loading, surface-to-volume ratio, sample stacking, mixing of samples with romaine lettuce, and shaking of the samples…”
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Does sensory quality assessed by beverage experts fit consumer acceptability? A study on cheongju by Byeon, Yang Soo, Heo, JeongAe, Kwak, Han Sub, Baek, Hyung Hee, Lee, Young‐seung, Kim, Sang Sook

“…Abstract Cheongju is traditional fermented liquor consisting of the filtered moieties of rice wine. In this study, the sensory quality of cheongjus judged by…”
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A Near-Infrared-Fluorescence-Quenched Gold-Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination by Lee, Seulki, Cha, Eui-Joon, Park, Kyeongsoon, Lee, Seung-Young, Hong, Jin-Ki, Sun, In-Cheol, Kim, Sang Yoon, Choi, Kuiwon, Kwon, Ick Chan, Kim, Kwangmeyung, Ahn, Cheol-Hee

“…Nanodiagnosis: A matrix‐metalloproteinase (MMP) sensitive gold‐nanoparticle (AuNP) imaging probe quenches conjugated near‐infrared (NIR) dyes with high…”
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SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells by Truong, Xuan T, Lee, Young-Seung, Nguyen, Thuy T P, Kim, Hyun-Jin, Kim, Sung-Hak, Moon, Changjong, Kim, Don-Kyu, Choi, Hueng-Sik, Jeon, Tae-Il

“…SMILE (small heterodimer partner-interacting leucine zipper protein) is a transcriptional corepressor that potently regulates various cellular processes such…”
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Three-dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart by Phillips, Evan H, Bindokas, Vytautas P, Jung, Dahee, Teamer, Jay, Kitajewski, Jan K, Solaro, R John, Wolska, Beata M, Lee, Steve Seung-Young

“…Three-dimensional (3D) microscopy and image data analysis are necessary for studying the morphology of cardiac lymphatic vessels (LyVs) and their association…”
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Quarantining: a mentally distressful but physically comfortable experience in South Korea by Kwon, Hye-Young, Kim, Yongjoo, Lee, Seung-Young, Kim, Chang-Bo

“…Abstract Objective Quarantine is the first response to the COVID-19 pandemic. Restricting daily life can cause several problems. This study aimed to measure…”
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Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing by Lee, Seung-Young, Huh, Myung Sook, Lee, Seulki, Lee, So Jin, Chung, Hyunjin, Park, Jae Hyung, Oh, Yu-Kyoung, Choi, Kuiwon, Kim, Kwangmeyung, Kwon, Ick Chan

“…Small interfering RNA (siRNA) is a promising biological strategy for treatment of diverse diseases, but the therapeutic application of siRNA has been limited…”
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The effect of surface functionalization of PLGA nanoparticles by heparin- or chitosan-conjugated Pluronic on tumor targeting by Chung, Yong-Il, Kim, Jong Chul, Kim, Young Ha, Tae, Giyoong, Lee, Seung-Young, Kim, Kwangmeyung, Kwon, Ick Chan

“…The poly (lactide-co-glycolide) (PLGA)-based nanoparticles, coated by the heparin- or chitosan-Pluronic conjugate, were used to improve a relatively low…”
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What Matters for Depression and Anxiety During the COVID-19 Quarantine?: Results of an Online Cross-Sectional Survey in Seoul, South Korea by Kwon, Hye-Young, Kim, Yongjoo, Lee, Seung-Young

“…Amid the COVID-19 pandemic, quarantine measures are key to containing the spread of the virus. Millions of people have been required to quarantine throughout…”
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Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice by Huh, Myung Sook, Lee, Seung-Young, Park, Sangjin, Lee, Seulki, Chung, Hyunjin, Lee, Sojin, Choi, Yongseok, Oh, Yu-Kyoung, Park, Jae Hyung, Jeong, Seo Young, Choi, Kuiwon, Kim, Kwangmeyung, Kwon, Ick Chan

“…Here, we designed a new nano-sized siRNA carrier system composed of biocompatible/biodegradable glycol chitosan polymer (GC) and strongly positively charged…”
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Tumor Targeting Chitosan Nanoparticles for Dual-Modality Optical/MR Cancer Imaging by Nam, Taehwan, Park, Sangjin, Lee, Seung-Young, Park, Kyeongsoon, Choi, Kuiwon, Song, In Chan, Han, Moon Hee, Leary, James J, Yuk, Simseok Andrew, Kwon, Ick Chan, Kim, Kwangmeyung, Jeong, Seo Young

“…We report tumor targeting nanoparticles for optical/MR dual imaging based on self-assembled glycol chitosan to be a potential multimodal imaging probe. To…”
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Polymeric Nanoparticle-Based Activatable Near-Infrared Nanosensor for Protease Determination In Vivo by Lee, Seulki, Ryu, Ju Hee, Park, Kyeongsoon, Lee, Aeju, Lee, Seung-Young, Youn, In-Chan, Ahn, Cheol-Hee, Yoon, Soon Man, Myung, Seung-Jae, Moon, Dae Hyuk, Chen, Xiaoyuan, Choi, Kuiwon, Kwon, Ick Chan, Kim, Kwangmeyung

“…We report here a new protease activatable strategy based on a polymer nanoparticle platform. This nanosensor delivers chemically labeled matrix…”
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis by Karginova, Olga, Weekley, Claire M, Raoul, Akila, Alsayed, Alhareth, Wu, Tong, Lee, Steve Seung-Young, He, Chuan, Olopade, Olufunmilayo I

“…Treatment of advanced breast cancer remains challenging. Copper and some of the copper-dependent proteins are emerging therapeutic targets because they are…”
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Targeted antibody and cytokine cancer immunotherapies through collagen affinity by Ishihara, Jun, Ishihara, Ako, Sasaki, Koichi, Lee, Steve Seung-Young, Williford, John-Michael, Yasui, Mariko, Abe, Hiroyuki, Potin, Lambert, Hosseinchi, Peyman, Fukunaga, Kazuto, Raczy, Michal M, Gray, Laura T, Mansurov, Aslan, Katsumata, Kiyomitsu, Fukayama, Masashi, Kron, Stephen J, Swartz, Melody A, Hubbell, Jeffrey A

“…Cancer immunotherapy with immune checkpoint inhibitors (CPIs) and interleukin-2 (IL-2) has demonstrated clinical efficacy but is frequently accompanied with…”
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Loss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2 by Lee, Eun-Ho, Lee, Jae-Ho, Kim, Do-Young, Lee, Young-Seung, Jo, Yunju, Dao, Tam, Kim, Kyung Eun, Song, Dae-Kyu, Seo, Ji Hae, Seo, Young-Kyo, Seong, Je Kyung, Moon, Changjong, Han, Eugene, Kim, Mi Kyung, Ryu, Seungwan, Shin, Minsang, Roh, Gu Seob, Jung, Hye Ra, Osborne, Timothy F., Ryu, Dongryeol, Jeon, Tae-Il, Im, Seung-Soon

“…Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis and is highly increased in…”
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In-vivo tumor targeting of pluronic-based nano-carriers by Kim, Ja-Young, Choi, Won Il, Kim, Young Ha, Tae, Giyoong, Lee, Seung-Young, Kim, Kwangmeyung, Kwon, Ick Chan

“…Pluronic-based nano-carriers including bare forms that were composed of Pluronic F 68(NC(PF 68)) or Pluronic F 127(NC(PF 127)), and chitosan-conjugated forms…”
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Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus by Baek, Yeong-Bin, Kwon, Hyung-Jun, Sharif, Muhammad, Lim, Jeongah, Lee, In-Chul, Ryu, Young Bae, Lee, Jae-In, Kim, Ji-Sun, Lee, Young-Seung, Kim, Dong-Hoon, Park, Sang-Ik, Kim, Don-Kyu, Kim, Jeong-Sun, Choy, Hyon E., Lee, Sunwoo, Choi, Hueng-Sik, Osborne, Timothy F., Jeon, Tae-Il, Cho, Kyoung-Oh

“…The biosynthesis of host lipids and/or lipid droplets (LDs) has been studied extensively as a putative therapeutic target in diverse viral infections. However,…”
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