Search Results - "Lee, Young K"

Use of radiomics for the prediction of local control of brain metastases after stereotactic radiosurgery by Mouraviev, Andrei, Detsky, Jay, Sahgal, Arjun, Ruschin, Mark, Lee, Young K, Karam, Irene, Heyn, Chris, Stanisz, Greg J, Martel, Anne L

“…Abstract Background Local response prediction for brain metastases (BM) after stereotactic radiosurgery (SRS) is challenging, particularly for smaller BM, as…”
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GATA2 is required for lymphatic vessel valve development and maintenance by Kazenwadel, Jan, Betterman, Kelly L, Chong, Chan-Eng, Stokes, Philippa H, Lee, Young K, Secker, Genevieve A, Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M, Sutton, Drew L, Tabruyn, Sebastien P, Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V, Matthews, Jacqueline M, Hahn, Christopher N, Scott, Hamish S, Harvey, Natasha L

“…Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including…”
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Varying Coefficient Regression Models: A Review and New Developments by Park, Byeong U., Mammen, Enno, Lee, Young K., Lee, Eun Ryung

“…Varying coefficient regression models are known to be very useful tools for analysing the relation between a response and a group of covariates. Their…”
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Salvage Stereotactic Body Radiotherapy (SBRT) Following In-Field Failure of Initial SBRT for Spinal Metastases by Thibault, Isabelle, MD, Campbell, Mikki, MRT(T), Tseng, Chia-Lin, MD, Atenafu, Eshetu G., MSc, Letourneau, Daniel, PhD, Yu, Eugene, MD, Cho, B.C. John, MD, Lee, Young K., PhD, Fehlings, Michael G., MD, PhD, Sahgal, Arjun, MD

“…Purpose We report our experience in salvaging spinal metastases initially irradiated with stereotactic body radiation therapy (SBRT), who subsequently…”
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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis by Lannagan, Tamsin R M, Lee, Young K, Wang, Tongtong, Roper, Jatin, Bettington, Mark L, Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A, Kobayashi, Hiroki, Putoczki, Tracey L, Hayakawa, Yoku, Leedham, Simon J, Abud, Helen E, Yilmaz, Ömer H, Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A, Whitehall, Vicki L J, Worthley, Daniel L, Woods, Susan L

“…Serrated colorectal cancer (CRC) accounts for approximately 25% of cases and includes tumours that are among the most treatment resistant and with worst…”
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Effects of Selective and Mixed-Action Kappa and Delta Opioid Receptor Agonists on Pain-Related Behavioral Depression in Mice by Negus, S Stevens, St Onge, Celsey M, Lee, Young K, Li, Mengchu, Rice, Kenner C, Zhang, Yan

“…We recently developed a series of nalfurafine analogs (TK10, TK33, and TK35) that may serve as non-addictive candidate analgesics. These compounds are…”
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Postoperative Stereotactic Body Radiotherapy for Spinal Metastases and the Impact of Epidural Disease Grade by Alghamdi, Majed, Sahgal, Arjun, Soliman, Hany, Myrehaug, Sten, Yang, Victor X D, Das, Sunit, Wilson, Jefferson, Campbell, Mikki, Lee, Young K, Cawricz, Monica, Da Costa, Leo, Atenafu, Eshetu G, Tseng, Chia-Lin

“…Abstract BACKGROUND Postoperative stereotactic body radiotherapy (pSBRT) is an emerging indication for spinal metastases (SM). OBJECTIVE To report our…”
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Dosimetric feasibility of the hybrid Magnetic Resonance Imaging (MRI)-linac System (MRL) for brain metastases: The impact of the magnetic field by Tseng, Chia-Lin, Eppinga, Wietse, Seravalli, Enrica, Hackett, Sara, Brand, Eric, Ruschin, Mark, Lee, Young K., Atenafu, Eshetu G., Sahgal, Arjun

“…We aimed to investigate the suitability of treating patients with single brain metastases using stereotactic radiosurgery (SRS) with the MRL and to…”
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Volume of Lytic Vertebral Body Metastatic Disease Quantified Using Computed Tomography–Based Image Segmentation Predicts Fracture Risk After Spine Stereotactic Body Radiation Therapy by Thibault, Isabelle, MD, Whyne, Cari M., PhD, Zhou, Stephanie, BSc, Campbell, Mikki, BSc, MRT(T), Atenafu, Eshetu G., MSc, PStat, Myrehaug, Sten, MD, Soliman, Hany, MD, Lee, Young K., PhD, Ebrahimi, Hamid, BSc, Yee, Albert J.M., MD, Sahgal, Arjun, MD

“…Purpose To determine a threshold of vertebral body (VB) osteolytic or osteoblastic tumor involvement that would predict vertebral compression fracture (VCF)…”
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Spine Stereotactic Body Radiotherapy: Indications, Outcomes, and Points of Caution by Tseng, Chia-Lin, Eppinga, Wietse, Charest-Morin, Raphaele, Soliman, Hany, Myrehaug, Sten, Maralani, Pejman Jabehdar, Campbell, Mikki, Lee, Young K., Fisher, Charles, Fehlings, Michael G., Chang, Eric L., Lo, Simon S., Sahgal, Arjun

“…Study Design: A broad narrative review. Objectives: The objective of this article is to provide a technical review of spine stereotactic body radiotherapy…”
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Development and Evaluation of Multiple Isocentric Volumetric Modulated Arc Therapy Technique for Craniospinal Axis Radiotherapy Planning by Lee, Young K., Ph.D, Brooks, Corrinne J., B.Sc, Bedford, James L., Ph.D, Warrington, Alan P., M.Sc, Saran, Frank H., M.D., F.R.C.R

“…Purpose To develop and compare a volumetric modulated arc therapy (VMAT) technique with conventional radiotherapy for craniospinal irradiation with respect to…”
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PIF4 Promotes Expression of LNG1 and LNG2 to Induce Thermomorphogenic Growth in Arabidopsis by Hwang, Geonhee, Zhu, Jia-Ying, Lee, Young K, Kim, Sara, Nguyen, Thom T, Kim, Jungmook, Oh, Eunkyoo

“…plants adapt to high ambient temperature by a suite of morphological changes including elongation of hypocotyls and petioles and leaf hyponastic growth. These…”
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Role of mu opioid receptor (MOR) agonist efficacy as a determinant of opioid antinociception in a novel assay of pain-depressed behavior in female and male mice by Negus, S Stevens, Akbarali, Hamid I, Kang, Minho, Lee, Young K, Marsh, Samuel A, Santos, Edna J, Zhang, Yan

“…Intermediate efficacy mu opioid receptor (MOR) agonists have potential to retain analgesic effectiveness while improving safety, but the optimal MOR efficacy…”
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Helical Volumetric Modulated Arc Therapy for Treatment of Craniospinal Axis by Bedford, James L., Ph.D, Lee, Young K., Ph.D, Saran, Frank H., M.D., F.R.C.R, Warrington, Alan P., M.Sc

“…Purpose Volumetric modulated arc therapy (VMAT) can be used with multiple isocenters to provide an effective treatment of the craniospinal axis. Additional…”
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Evaluation of multi-institutional end-to-end testing for post-operative spine stereotactic body radiation therapy by Furuya, Tomohisa, Lee, Young K., Archibald-Heeren, Ben R., Byrne, Mikel, Bosco, Bruno, Phua, Jun H., Shimizu, Hidetoshi, Hashimoto, Shimpei, Tanaka, Hiroshi, Sahgal, Arjun, Karasawa, Katsuyuki

“…•Post-operative spine SBRT may be a therapeutic option for patients with metal fixation.•Evaluation of accuracy of dose prescription is a significant…”
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The proinflammatory LTB4/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region by Jeon, Woo-Kwang, Choi, Jiyeon, Park, Seong Ji, Jo, Eun Ji, Lee, Young K, Lim, Seunghwan, Kim, Jae-Hong, Letterio, John J, Liu, Fang, Kim, Seong-Jin, Kim, Byung-Chul

“…Leukotriene B4 (LTB4) is a potent pro-inflammatory eicosanoid that is derived from arachidonic acid, and its signaling is known to have a tumor-promoting role…”
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Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat by Lee, Sang M, Yune, Tae Y, Kim, Sun J, Park, Do W, Lee, Young K, Kim, Young C, Oh, Young J, Markelonis, George J, Oh, Tae H

“…We examined the effects of minocycline, an anti-inflammatory drug, on functional recovery following spinal cord injury (SCI). Rats received a mild, weight-drop…”
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Imaging-Based Outcomes for 24 Gy in 2 Daily Fractions for Patients with de Novo Spinal Metastases Treated With Spine Stereotactic Body Radiation Therapy (SBRT) by Tseng, Chia-Lin, Soliman, Hany, Myrehaug, Sten, Lee, Young K., Ruschin, Mark, Atenafu, Eshetu G., Campbell, Mikki, Maralani, Pejman, Yang, Victor, Yee, Albert, Sahgal, Arjun

“…We report mature outcomes for a cohort of patients with no prior radiation (de novo) to the spine treated with 24 Gy in 2 daily fractions for metastases, which…”
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Backfitting and smooth backfitting for additive quantile models by Lee, Young K., Mammen, Enno, Park, Byeong U.

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Beyond Performance: A Motivational Experiences Model of Stereotype Threat by Thoman, Dustin B., Smith, Jessi L., Brown, Elizabeth R., Chase, Justin, Lee, Joo Young K.

“…The contributing role of stereotype threat (ST) to learning and performance decrements for stigmatized students in highly evaluative situations has been vastly…”
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