A case of Clostridium difficile infection complicated by acute respiratory distress syndrome treated with fecal microbiota transplantation

Acute respiratory distress syndrome is a life-threatening disorder caused mainly by pneumonia.Clostridium difficile infection(CDI)is a common nosocomial diarrheal disease.Disruption of normal intestinal flora by antibiotics is the main risk factor for CDI.The use of broadspectrum antibiotics for ser...

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Published in:World journal of gastroenterology : WJG Vol. 20; no. 35; pp. 12687 - 12690
Main Authors: Kim, Ji Eun, Gweon, Tae-Geun, Yeo, Chang Dong, Cho, Young-Seok, Kim, Gi Jun, Kim, Jae Young, Kim, Jong Wook, Kim, Hyunho, Lee, Hye Won, Lim, Taeseok, Ham, Hyoju, Oh, Hyun Jin, Lee, Yeongbok, Byeon, Jaeho, Park, Sung Soo
Format: Journal Article
Language:English
Published: United States Baishideng Publishing Group Inc 21-09-2014
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Summary:Acute respiratory distress syndrome is a life-threatening disorder caused mainly by pneumonia.Clostridium difficile infection(CDI)is a common nosocomial diarrheal disease.Disruption of normal intestinal flora by antibiotics is the main risk factor for CDI.The use of broadspectrum antibiotics for serious medical conditions can make it difficult to treat CDI complicated by acute respiratory distress syndrome.Fecal microbiota transplantation is a highly effective treatment in patients with refractory CDI.Here we report on a patient with refractory CDI and acute respiratory distress syndrome caused by pneumonia who was treated with fecal microbiota transplantation.
Bibliography:Ji Eun Kim;Tae-Geun Gweon;Chang Dong Yeo;Young-Seok Cho;Gi Jun Kim;Jae Young Kim;Jong Wook Kim;Hyunho Kim;Hye Won Lee;Taeseok Lim;Hyoju Ham;Hyun Jin Oh;Yeongbok Lee;Jaeho Byeon;Sung Soo Park;Department of Internal Medicine,Seoul St Mary’s hospital,The Catholic University of Korea,College of Medicine;Division of Gastroenterology,Department of Internal Medicine,Seoul St.Mary’s Hospital,The Catholic University of Korea,College of Medicine;Division of Pulmonology,Department of Internal Medicine,Uijeongbu St.Mary’s Hospital,The Catholic University of Korea,College of Medicine;Division of Gastroenterology,Department of Internal Medicine,Uijeongbu St.Mary’s Hospital,The Catholic University of Korea,College of Medicine
Correspondence to: Chang Dong Yeo, MD, Division of Pulmonology, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, The Catholic University of Korea, College of Medicine, 65-1, Geumodong, Uijeongbu, Gyeonggi 480-821, South Korea. brainyeo@catholic.ac.kr
Telephone: +82-31-8203893 Fax: +82-31-8472719
Author contributions: Kim JE and Gweon TG wrote the paper; Gweon TG, Cho YS, Kim GJ, Kim JY and Byeon J conducted fecal microbiota transplantation; Yeo CD, Kim JW and Kim H contributed to ventilator care; Lee HW, Lim T, Ham H and Park SS collected data; Oh HJ and Lee Y conducted language editing; Gweon TG and Yeo CD edited the paper and approved the final version.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i35.12687