Search Results - "Lee, Vivian K"
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Creating perfused functional vascular channels using 3D bio-printing technology
Published in Biomaterials (01-09-2014)“…Abstract We developed a methodology using 3D bio-printing technology to create a functional in vitro vascular channel with perfused open lumen using only cells…”
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2
Engineering transferrable microvascular meshes for subcutaneous islet transplantation
Published in Nature communications (10-10-2019)“…The success of engineered cell or tissue implants is dependent on vascular regeneration to meet adequate metabolic requirements. However, development of a…”
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Generation of Multi-scale Vascular Network System Within 3D Hydrogel Using 3D Bio-printing Technology
Published in Cellular and molecular bioengineering (01-09-2014)“…Although 3D bio-printing technology has great potential in creating complex tissues with multiple cell types and matrices, maintaining the viability of thick…”
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4
Intravenous Acetaminophen
Published in Anesthesiology clinics (01-12-2010)“…Acetaminophen has unique analgesic and antipyretic properties. It is globally recommended as a first-line agent for the treatment of fever and pain due to its…”
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Printing of Three-Dimensional Tissue Analogs for Regenerative Medicine
Published in Annals of biomedical engineering (01-01-2017)“…Three-dimensional (3-D) cell printing, which can accurately deposit cells, biomaterial scaffolds and growth factors in precisely defined spatial patterns to…”
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Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
Published in Communications biology (29-01-2021)“…Infiltrative growth is a major cause of high lethality of malignant brain tumors such as glioblastoma (GBM). We show here that GBM cells upregulate guidance…”
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The integration of 3-D cell printing and mesoscopic fluorescence molecular tomography of vascular constructs within thick hydrogel scaffolds
Published in Biomaterials (01-07-2012)“…Abstract Developing methods that provide adequate vascular perfusion is an important step toward engineering large functional tissues. Meanwhile, an imaging…”
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8
High-resolution tomographic analysis of in vitro 3D glioblastoma tumor model under long-term drug treatment
Published in Science advances (01-03-2020)“…Glioblastoma multiforme (GBM) is a lethal type of brain tumor that often develop therapeutic resistance over months of chemotherapy cycles. Recently, 3D GBM…”
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An architecturally rational hemostat for rapid stopping of massive bleeding on anticoagulation therapy
Published in Proceedings of the National Academy of Sciences - PNAS (30-01-2024)“…Hemostatic devices are critical for managing emergent severe bleeding. With the increased use of anticoagulant therapy, there is a need for next-generation…”
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Mesoscopic fluorescence molecular tomography of reporter genes in bioprinted thick tissue
Published in Journal of biomedical optics (01-10-2013)“…Three-dimensional imaging of thick tissue constructs is one of the main challenges in the field of tissue engineering and regenerative medicine. Optical…”
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BTBR ob/ob mouse model of type 2 diabetes exhibits early loss of retinal function and retinal inflammation followed by late vascular changes
Published in Diabetologia (01-11-2018)“…Aims/hypothesis Diabetic retinopathy is increasing in prevalence worldwide and is fast becoming a global epidemic and a leading cause of visual loss. Current…”
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Reduced Glomerular Filtration in Diabetes Is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations
Published in Journal of the American Society of Nephrology (01-06-2022)“…Glomerular endothelial cell (GEnC) fenestrations are recognized as an essential component of the glomerular filtration barrier, yet little is known about how…”
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Computer-based Insulin Infusion Protocol Improves Glycemia Control over Manual Protocol
Published in Journal of the American Medical Informatics Association : JAMIA (01-05-2007)“…Hyperglycemia worsens clinical outcomes in critically ill patients. Precise glycemia control using intravenous insulin improves outcomes. To determine if we…”
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14
Formulating medication adherence strategies using the PASSAction framework
Published in Canadian pharmacists journal (01-01-2013)“…Adherence, as defined by the World Health Organization, is the extent to which a persons behaviour-taking medication, following a diet and/or executing…”
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Generation of 3-D glioblastoma-vascular niche using 3-D bioprinting
Published in 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) (01-04-2015)“…Glioblastoma multiforme (GBM), a malignant brain tumor, frequently exploit microvessels as guides for migration. Understanding cell-cell interaction between…”
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Conference Proceeding -
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Construction of 3D tissue with perfused vessels and capillaries through 3D bio-printing
Published in 2014 40th Annual Northeast Bioengineering Conference (NEBEC) (01-04-2014)“…Due to diffusion limitation, tissues thicker than several hundred micrometers have difficulties in survival and proliferation. 3D bio-printing technology…”
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Conference Proceeding -
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Laminar Optical Tomography Applied to Reporter Genes Imaging in Engineered Tissue Constructs
Published in 2013 39th Annual Northeast Bioengineering Conference (01-04-2013)“…Fluorescence imaging is the main method in assessing tissue engineered constructs. However, with the drive to develop thick engineered constructs, it is…”
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Conference Proceeding -
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Clinical and radiological aspects in Melnick-Needles syndrome
Published in Revista do Hospital das Clinicás (01-04-1999)“…Melnick-Needles syndrome is an X-linked dominant bone dysplasia, lethal in males, characterized by a typical facies and characteristic radiological findings:…”
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