Search Results - "Lee, Vernon"

Can we contain the COVID-19 outbreak with the same measures as for SARS? by Wilder-Smith, Annelies, Chiew, Calvin J, Lee, Vernon J

“…The severe acute respiratory syndrome (SARS) outbreak in 2003 resulted in more than 8000 cases and 800 deaths. SARS was eventually contained by means of…”
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Interrupting transmission of COVID-19: lessons from containment efforts in Singapore by Lee, Vernon J, Chiew, Calvin J, Khong, Wei Xin

“…Despite multiple importations resulting in local chains of transmission, Singapore has been able to control the COVID-19 outbreak without major disruption to…”
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Connecting clusters of COVID-19: an epidemiological and serological investigation by Yong, Sarah Ee Fang, Anderson, Danielle Elizabeth, Wei, Wycliffe E, Pang, Junxiong, Chia, Wan Ni, Tan, Chee Wah, Teoh, Yee Leong, Rajendram, Priyanka, Toh, Matthias Paul Han Sim, Poh, Cuiqin, Koh, Valerie T J, Lum, Joshua, Suhaimi, Nur-Afidah Md, Chia, Po Ying, Chen, Mark I-Cheng, Vasoo, Shawn, Ong, Benjamin, Leo, Yee Sin, Wang, Linfa, Lee, Vernon J M

“…Elucidation of the chain of disease transmission and identification of the source of coronavirus disease 2019 (COVID-19) infections are crucial for effective…”
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Decreased Influenza Incidence under COVID-19 Control Measures, Singapore by Soo, Roy Jiunn Jye, Chiew, Calvin J, Ma, Stefan, Pung, Rachael, Lee, Vernon

“…We compared indicators of influenza activity in 2020 before and after public health measures were taken to reduce coronavirus disease (COVID-19) with the…”
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Infectivity of asymptomatic versus symptomatic COVID-19 by Sayampanathan, Andrew A, Heng, Cheryl S, Pin, Phua Hwee, Pang, Junxiong, Leong, Teoh Yee, Lee, Vernon J

“…Asymptomatic cases of COVID-19 are a potential source of substantial spread within the community setting.1 However, little information is available about the…”
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Clinical and Virological Features of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern: A Retrospective Cohort Study Comparing B.1.1.7 (Alpha), B.1.351 (Beta), and B.1.617.2 (Delta) by Ong, Sean Wei Xiang, Chiew, Calvin J, Ang, Li Wei, Mak, Tze Minn, Cui, Lin, Toh, Matthias Paul H S, Lim, Yi Ding, Lee, Pei Hua, Lee, Tau Hong, Chia, Po Ying, Maurer-Stroh, Sebastian, Lin, Raymond T P, Leo, Yee Sin, Lee, Vernon J, Lye, David Chien, Young, Barnaby Edward

“…Abstract Background The impact of SARS-CoV-2 variants of concern (VOCs) on disease severity is unclear. In this retrospective study, we compared the outcomes…”
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Serial intervals in SARS-CoV-2 B.1.617.2 variant cases by Pung, Rachael, Mak, Tze Minn, Kucharski, Adam J, Lee, Vernon J

“…In particular, an increase in observed growth rate of COVID-19 cases could be the result of a shorter generation interval (ie, the delay from one infection to…”
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Epidemic preparedness in urban settings: new challenges and opportunities by Lee, Vernon J, Ho, Marc, Kai, Chen Wen, Aguilera, Ximena, Heymann, David, Wilder-Smith, Annelies

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Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study by Chia, Po Ying, Ong, Sean Wei Xiang, Chiew, Calvin J., Ang, Li Wei, Chavatte, Jean-Marc, Mak, Tze-Minn, Cui, Lin, Kalimuddin, Shirin, Chia, Wan Ni, Tan, Chee Wah, Chai, Louis Yi Ann, Tan, Seow Yen, Zheng, Shuwei, Lin, Raymond Tzer Pin, Wang, Linfa, Leo, Yee-Sin, Lee, Vernon J., Lye, David Chien, Young, Barnaby Edward

“…Highly effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed but variants of concerns are worrisome,…”
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Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study by Young, Barnaby E, Fong, Siew-Wai, Chan, Yi-Hao, Mak, Tze-Minn, Ang, Li Wei, Anderson, Danielle E, Lee, Cheryl Yi-Pin, Amrun, Siti Naqiah, Lee, Bernett, Goh, Yun Shan, Su, Yvonne C F, Wei, Wycliffe E, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Chen, Yuan Yi Constance, Barkham, Timothy, Lin, Raymond Tzer Pin, Maurer-Stroh, Sebastian, Leo, Yee-Sin, Wang, Lin-Fa, Renia, Laurent, Lee, Vernon J, Smith, Gavin J D, Lye, David Chien, Ng, Lisa F P

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a 382-nucleotide deletion (∆382) in the open reading frame 8 (ORF8) region of the…”
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Protective immunity of SARS-CoV-2 infection and vaccines against medically attended symptomatic omicron BA.4, BA.5, and XBB reinfections in Singapore: a national cohort study by Tan, Celine Y, Chiew, Calvin J, Pang, Deanette, Lee, Vernon J, Ong, Benjamin, Lye, David Chien, Tan, Kelvin Bryan

“…Despite a large proportion of the population having been vaccinated and infected, Singapore had SARS-CoV-2 waves driven by the BA.5 and XBB sublineages of the…”
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Comparative Effectiveness of mRNA and Inactivated Whole-Virus Vaccines Against Coronavirus Disease 2019 Infection and Severe Disease in Singapore by Premikha, M, Chiew, Calvin J, Wei, Wycliffe E, Leo, Yee Sin, Ong, Benjamin, Lye, David Chien, Lee, Vernon J, Tan, Kelvin Bryan

“…Compared with individuals vaccinated with Pfizer-BioNTech/Comirnaty, recipients of Sinovac-CoronaVac and Sinopharm were 2.37 (95% CI, 2.29-2.46) and 1.62 (95%…”
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SARS-CoV-2 seroprevalence and transmission risk factors among high-risk close contacts: a retrospective cohort study by Ng, Oon Tek, Marimuthu, Kalisvar, Koh, Vanessa, Pang, Junxiong, Linn, Kyaw Zaw, Sun, Jie, De Wang, Liang, Chia, Wan Ni, Tiu, Charles, Chan, Monica, Ling, Li Min, Vasoo, Shawn, Abdad, Mohammad Yazid, Chia, Po Ying, Lee, Tau Hong, Lin, Ray Junhao, Sadarangani, Sapna P, Chen, Mark I-Cheng, Said, Zubaidah, Kurupatham, Lalitha, Pung, Rachael, Wang, Lin-Fa, Cook, Alex R, Leo, Yee-Sin, Lee, Vernon JM

“…The proportion of asymptomatic carriers and transmission risk factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among household and…”
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Presymptomatic Transmission of SARS-CoV-2 - Singapore, January 23-March 16, 2020 by Wei, Wycliffe E, Li, Zongbin, Chiew, Calvin J, Yong, Sarah E, Toh, Matthias P, Lee, Vernon J

“…Presymptomatic transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), might pose challenges for disease control. The first case…”
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SARS-CoV-2 Infection among Travelers Returning from Wuhan, China by Ng, Oon-Tek, Marimuthu, Kalisvar, Chia, Po-Ying, Koh, Vanessa, Chiew, Calvin J, De Wang, Liang, Young, Barnaby E, Chan, Monica, Vasoo, Shawn, Ling, Li-Min, Lye, David C, Kam, Kai-qian, Thoon, Koh-Cheng, Kurupatham, Lalitha, Said, Zubaidah, Goh, Ethan, Low, Constance, Lim, Soon-Kok, Raj, Pream, Oh, Olivia, Koh, Valerie T.J, Poh, Cuiqin, Mak, Tze-Minn, Cui, Lin, Cook, Alex R, Lin, Raymond T.P, Leo, Yee-Sin, Lee, Vernon J.M

“…Data on travelers returning from areas with many cases of Covid-19 may be useful in estimating incidence. The authors report follow-up data on 94 persons who…”
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Epidemiological and Clinical Predictors of COVID-19 by Sun, Yinxiaohe, Koh, Vanessa, Marimuthu, Kalisvar, Ng, Oon Tek, Young, Barnaby, Vasoo, Shawn, Chan, Monica, Lee, Vernon J M, De, Partha P, Barkham, Timothy, Lin, Raymond T P, Cook, Alex R, Leo, Yee Sin

“…Abstract Background Rapid identification of COVID-19 cases, which is crucial to outbreak containment efforts, is challenging due to the lack of pathognomonic…”
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Health-seeking behavior of COVID-19 cases during the first eight weeks of the outbreak in Singapore: differences between local community and imported cases and having visits to single or multiple healthcare providers by Tay, Min Zhi, Ang, Li Wei, Wei, Wycliffe Enli, Lee, Vernon J M, Leo, Yee-Sin, Toh, Matthias Paul H S

“…COVID-19 is a novel pandemic affecting almost all countries leading to lockdowns worldwide. In Singapore, locally-acquired cases emerged after the first wave…”
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Seroprevalence of antibodies against chikungunya virus in Singapore resident adult population by Ang, Li Wei, Kam, Yiu Wing, Lin, Cui, Krishnan, Prabha Unny, Tay, Joanne, Ng, Lee Ching, James, Lyn, Lee, Vernon J M, Goh, Kee Tai, Ng, Lisa F P, Lin, Raymond T P

“…We determined the seroprevalence of chikungunya virus (CHIKV) infection in the adult resident population in Singapore following local outbreaks of chikungunya…”
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Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures by Pung, Rachael, Chiew, Calvin J, Young, Barnaby E, Chin, Sarah, Chen, Mark I-C, Clapham, Hannah E, Cook, Alex R, Maurer-Stroh, Sebastian, Toh, Matthias P H S, Poh, Cuiqin, Low, Mabel, Lum, Joshua, Koh, Valerie T J, Mak, Tze M, Cui, Lin, Lin, Raymond V T P, Heng, Derrick, Leo, Yee-Sin, Lye, David C, Lee, Vernon J M, Kam, Kai-qian, Kalimuddin, Shirin, Tan, Seow Yen, Loh, Jiashen, Thoon, Koh Cheng, Vasoo, Shawn, Khong, Wei Xin, Suhaimi, Nur-Afidah, Chan, Sherlynn JH, Zhang, Emma, Oh, Olivia, Ty, Albert, Tow, Charlene, Chua, Yi Xian, Chaw, Wei Liang, Ng, Yixiang, Abdul-Rahman, Farid, Sahib, Shafiq, Zhao, Zheng, Tang, Cheryl, Low, Constance, Goh, Ee Hui, Lim, Georgina, Hou, Yan'an, Roshan, Imran, Tan, James, Foo, Kelly, Nandar, Khine, Kurupatham, Lalitha, Chan, Pei Pei, Raj, Pream, Lin, Yijun, Said, Zubaidah, Lee, Anne, See, Cherie, Markose, Jessey, Tan, Joanna, Chan, Guanhao, See, Wanhan, Peh, Xinyi, Cai, Vincent, Chen, Wen Kai, Li, Zongbin, Soo, Roy, Chow, Angela LP, Wei, Wycliffe, Farwin, Aysha, Ang, Li Wei

“…Three clusters of coronavirus disease 2019 (COVID-19) linked to a tour group from China, a company conference, and a church were identified in Singapore in…”
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Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Pediatric Age on Delta Variant Household Transmission by Ng, Oon Tek, Koh, Vanessa, Chiew, Calvin J, Marimuthu, Kalisvar, Thevasagayam, Natascha May, Mak, Tze Minn, Chua, Joon Kiat, Ong, Shannen Si Hui, Lim, Yong Kai, Ferdous, Zannatul, Johari, Alifa Khairunnisa bte, Cui, Lin, Lin, Raymond Tzer Pin, Tan, Kelvin Bryan, Cook, Alex R, Leo, Yee Sin, Lee, Vernon J M

“…Abstract Background In Singapore, quarantine of all close contacts with entry and exit polymerase chain reaction testing enabled evaluation of the impact of…”
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