Search Results - "Lee, Todd C."

Propofol and survival: an updated meta-analysis of randomized clinical trials by Kotani, Yuki, Pruna, Alessandro, Turi, Stefano, Borghi, Giovanni, Lee, Todd C, Zangrillo, Alberto, Landoni, Giovanni, Pasin, Laura

“…Propofol is one of the most widely used hypnotic agents in the world. Nonetheless, propofol might have detrimental effects on clinically relevant outcomes,…”
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A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19 by Boulware, David R, Pullen, Matthew F, Bangdiwala, Ananta S, Pastick, Katelyn A, Lofgren, Sarah M, Okafor, Elizabeth C, Skipper, Caleb P, Nascene, Alanna A, Nicol, Melanie R, Abassi, Mahsa, Engen, Nicole W, Cheng, Matthew P, LaBar, Derek, Lother, Sylvain A, MacKenzie, Lauren J, Drobot, Glen, Marten, Nicole, Zarychanski, Ryan, Kelly, Lauren E, Schwartz, Ilan S, McDonald, Emily G, Rajasingham, Radha, Lee, Todd C, Hullsiek, Kathy H

“…In this double-blind, randomized trial, 821 asymptomatic persons with a high-risk or moderate-risk exposure to SARS-CoV-2 were assigned to receive…”
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Comment to: "Propofol and survival: an updated meta-analysis of randomized clinical trials": authors' reply by Kotani, Yuki, Pruna, Alessandro, Lee, Todd C, Roth, Dominik, Landoni, Giovanni

“…[...]the mortality benefit of low molecular weight heparins in severe COVID-19 patients was not demonstrable in the initial trials but has been shown in…”
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Authors' reply to the comment from Benavides-Zora et al by Kotani, Yuki, Pruna, Alessandro, Lee, Todd C, Roth, Dominik, Landoni, Giovanni

“…Even if our analysis would violate the proportional hazards assumption, this would only lead to an underestimation of pooled effect size, further strengthening…”
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Authors' reply to Hansel's letter to the editor by Kotani, Yuki, Pruna, Alessandro, Lee, Todd C, Landoni, Giovanni

“…Variations in follow-up time have been described in critical care settings and in meta-regression, these were not found to influence pooled point estimates of…”
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Authors’ reply to the comment from Glass et al by Kotani, Yuki, Pruna, Alessandro, Belletti, Alessandro, Lee, Todd C, Landoni, Giovanni

“…[...]we confirm the correct exclusion of our large MYRIAD randomized controlled trial (RCT) with patients receiving either total intravenous anesthesia (TIVA)…”
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Review: Hydroxychloroquine and Chloroquine for Treatment of SARS-CoV-2 (COVID-19) by Pastick, Katelyn A, Okafor, Elizabeth C, Wang, Fan, Lofgren, Sarah M, Skipper, Caleb P, Nicol, Melanie R, Pullen, Matthew F, Rajasingham, Radha, McDonald, Emily G, Lee, Todd C, Schwartz, Ilan S, Kelly, Lauren E, Lother, Sylvain A, Mitjà, Oriol, Letang, Emili, Abassi, Mahsa, Boulware, David R

“…Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly emerging viral infection causing coronavirus disease 2019 (COVID-19)…”
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An observational cohort study of hydroxychloroquine and azithromycin for COVID-19: (Can’t Get No) Satisfaction by Lee, Todd C., MacKenzie, Lauren J, McDonald, Emily G., Tong, Steven Y.C.

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Hepatitis B testing practices at a tertiary care centre and their associated costs: A retrospective analysis by Lawandi, Alexander, Cheng, Matthew P, Lee, Todd C

“…Hepatitis B is a viral infection requiring specific serologic testing to diagnose the stage of the disease. There are many tests which can be ordered in a…”
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Hydroxychloroquine for COVID19: The curtains close on a comedy of errors by Schwartz, Ilan S, Boulware, David R, Lee, Todd C

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Remdesivir and systemic corticosteroids for the treatment of COVID-19: A Bayesian re-analysis by Lee, Todd C., McDonald, Emily G., Butler-Laporte, Guillaume, Harrison, Luke B., Cheng, Matthew P., Brophy, James M.

“…•A Bayesian re-analysis of remdesivir and corticosteroid randomized controlled trials was conducted.•Probabilities that remdesivir and corticosteroids reduced…”
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Back to the Future: Penicillin-Susceptible Staphylococcus Aureus by Cheng, Matthew P., MDCM, René, Pierre, MD, Cheng, Alexandre P., DEC, Lee, Todd C., MD

“…Synopsis Background Widespread penicillin usage rapidly resulted in the emergence of penicillin resistance in Staphylococcus aureus . However, new data…”
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Prevalence of medication overload among older people with HIV: a MedSafer study by Bortolussi-Courval, Émilie, Smyth, Elizabeth, Costiniuk, Cecilia, Falutz, Julian, Ross, Sydney B, Liu, Kathy, Lee, Jimin J, Sheehan, Nancy L, Lee, Todd C, McDonald, Emily G

“…Older people with HIV (PWH) are at risk of polypharmacy (taking multiple medications). Most medications may be necessary and indicated to manage HIV (e.g.,…”
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Development of a clinical risk score for the prediction of Pneumocystis jirovecii pneumonia in hospitalised patients by Mappin-Kasirer, Benjamin, Del Corpo, Olivier, Gingras, Marc-Alexandre, Hass, Aaron, Hsu, Jimmy M, Costiniuk, Cecilia T, Ezer, Nicole, Fraser, Richard S, Lee, Todd C, McDonald, Emily G

“…The performance and availability of invasive and non-invasive investigations for the diagnosis of Pneumocystis jirovecii pneumonia (PCP) vary across clinical…”
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Web and phone-based COVID-19 syndromic surveillance in Canada: A cross-sectional study by Lapointe-Shaw, Lauren, Rader, Benjamin, Astley, Christina M, Hawkins, Jared B, Bhatia, Deepit, Schatten, William J, Lee, Todd C, Liu, Jessica J, Ivers, Noah M, Stall, Nathan M, Gournis, Effie, Tuite, Ashleigh R, Fisman, David N, Bogoch, Isaac I, Brownstein, John S

“…Syndromic surveillance through web or phone-based polling has been used to track the course of infectious diseases worldwide. Our study objective was to…”
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Predictive factors of Clostridioides difficile infection in hospitalized patients with new diarrhea: A retrospective cohort study by Demir, Koray K, Cheng, Matthew P, Lee, Todd C

“…Diagnostic testing for Clostridioides difficile infection (CDI) by nucleic acid amplification test (NAAT) cannot distinguish between colonization and…”
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Mindfulness-based laboratory reduction: reducing utilization through trainee-led daily “time outs” by McDonald, Emily G., MD MSc, Saleh, Ramy R., MD, Lee, Todd C., MD MPH

“…Abstract Background Overuse of laboratory investigations is widely prevalent in hospitalized patients, leads to discomfort, and increases direct and indirect…”
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Staphylococcus aureus bacteremia mortality across country income groups: A secondary analysis of a systematic review by Bai, Anthony D, Lo, Carson KL, Komorowski, Adam S, Suresh, Mallika, Guo, Kevin, Garg, Akhil, Tandon, Pranav, Senecal, Julien, Corpo, Olivier Del, Stefanova, Isabella, Fogarty, Clare, Butler-Laporte, Guillaume, McDonald, Emily G, Cheng, Matthew P, Morris, Andrew M, Loeb, Mark, Lee, Todd C

“…•Styphylococcus aureus bacteremia (SAB) is common in low and middle-income countries (LMIC).•LMIC are poorly represented in SAB research.•In-hospital mortality…”
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Comparative effectiveness of amphotericin B, azoles and echinocandins in the treatment of candidemia and invasive candidiasis: A systematic review and network meta‐analysis by Demir, Koray K., Butler‐Laporte, Guillaume, Del Corpo, Olivier, Ekmekjian, Taline, Sheppard, Donald C., Lee, Todd C., Cheng, Matthew P.

“…Background + Objectives The echinocandins, amphotericin B preparations, voriconazole and fluconazole are approved for the treatment of invasive candidiasis,…”
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Radiographic features in investigated for Pneumocystis jirovecii pneumonia: a nested case-control study by Hsu, Jimmy M, Hass, Aaron, Gingras, Marc-Alexandre, Chong, Jaron, Costiniuk, Cecilia, Ezer, Nicole, Fraser, Richard S, McDonald, Emily G, Lee, Todd C

“…Abstract Background Pneumocystis jirovecii pneumonia (PJP) can be challenging to diagnose, often requiring bronchoscopy. Since most patients suspected of PJP…”
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