Search Results - "Lee, Timothy Dg"

Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy by Devitt, Jennifer J, King, Chelsey L, Lee, Timothy D G, Hancock Friesen, Camille L

“…Ischemia/reperfusion induced innate immune injury is inescapable in solid organ transplantation. Prolonged cold ischemia exacerbates the primary manifestation…”
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Neutrophil mediated smooth muscle cell loss precedes allograft vasculopathy by King, Chelsey L, Devitt, Jennifer J, Lee, Timothy D G, Hancock Friesen, Camille L

“…Cardiac allograft vasculopathy (AV) is a pathological process of vascular remodeling leading to late graft loss following cardiac transplantation. While there…”
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Myocardial fibrosis in response to Angiotensin II is preceded by the recruitment of mesenchymal progenitor cells by Sopel, Mryanda J, Rosin, Nicole L, Lee, Timothy DG, Légaré, Jean-Francois

“…Myocardial fibrosis is characterized by significant extracellular matrix (ECM) deposition. The specific cellular mediators that contribute to the development…”
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Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis by Sopel, Mryanda, Falkenham, Alec, Oxner, Adam, Ma, Irene, Lee, Timothy D.G., Légaré, Jean-Francois

“…Summary Using an established model of myocardial hypertrophy and fibrosis after angiotensin II (AngII) infusion, our aim was to characterize the early cellular…”
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Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay by Webster, Duncan, Lee, Timothy D G, Moore, Jill, Manning, Tracy, Kunimoto, Dennis, LeBlanc, Darren, Johnson, John A, Gray, Christopher A

“…Multidrug-resistant Mycobacterium tuberculosis strains have rapidly become a global health concern. North American First Nations communities have used…”
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IFN-g and Fas/FasL pathways cooperate to induce medial cell loss and neointimal lesion formation in allograft vasculopathy by Hart-Matyas, Michael, Nejat, Sara, Jordan, Julie L, Hirsch, Gregory M, Lee, Timothy DG

“…Using a clinically relevant, fully disparate, allogeneic aortic transplant mouse model of allograft vasculopathy, we have demonstrated that neointimal…”
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Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis by Rosin, Nicole L, Gareau, Alison J, Betsch, Devin, Falkenham, Alec, Sopel, Mryanda J, Lee, Timothy Dg, Légaré, Jean-Francois

“…Myocardial fibrosis is a pathological process that is characterized by disrupted regulation of extracellular matrix proteins resulting in permanent scarring of…”
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CD8 super(+) T cells mediate aortic allograft vasculopathy under conditions of calcineurin immunosuppression: Role of IFN- gamma and CTL mediators by Nejat, Sara, Zaki, Amr, Hirsch, Gregory M, Lee, Timothy DG

“…We have developed a model of aortic allograft vasculopathy (AV) that uses mouse strains that are fully disparate at Class I, Class II and minor…”
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Immunologic targets in the etiology of allograft vasculopathy: Endothelium versus media by Currie, Maria, Zaki, Amr M, Nejat, Sara, Hirsch, Gregory M, Lee, Timothy D.G

“…Abstract The respective roles of the endothelium and the media as allo-immune targets in the generation of allograft vasculopathy (AV) have yet to be clearly…”
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Contribution of pre-existing vascular disease to allograft vasculopathy in a murine model by Zaki, Amr M, Hirsch, Gregory M, Lee, Timothy D.G

“…Abstract Allograft vasculopathy (AV) has emerged as a major obstacle for long-term graft survival after cardiac transplantation. The shortage of donor hearts…”
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