Search Results - "Lee, Terence K"

FSTL1 Secreted by Activated Fibroblasts Promotes Hepatocellular Carcinoma Metastasis and Stemness by Loh, Jia-Jian, Li, Tsz-Wai, Zhou, Lei, Wong, Tin-Lok, Liu, Xue, Ma, Victor W S, Lo, Chung-Mau, Man, Kwan, Lee, Terence K, Ning, Wen, Tong, Man, Ma, Stephanie

“…The tumor microenvironment plays a critical role in maintaining the immature phenotype of tumor-initiating cells (TIC) to promote cancer. Hepatocellular…”
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Efficacy of annexin A3 blockade in sensitizing hepatocellular carcinoma to sorafenib and regorafenib by Tong, Man, Che, Noélia, Zhou, Lei, Luk, Steve T., Kau, Phillis W., Chai, Stella, Ngan, Elly S., Lo, Chung-Mau, Man, Kwan, Ding, Jin, Lee, Terence K., Ma, Stephanie

“…[Display omitted] •ANXA3 confers HCC cells with the ability to resist sorafenib.•ANXA3 is enriched in sorafenib-resistant HCC.•ANXA3 activates autophagy and…”
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IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma by Cheng, Bowie Y, Lau, Eunice Y, Leung, Hoi-Wing, Leung, Carmen Oi-Ning, Ho, Nicole P, Gurung, Shilpa, Cheng, Lily K, Lin, Chi Ho, Lo, Regina Cheuk-Lam, Ma, Stephanie, Ng, Irene Oi-Lin, Lee, Terence K

“…Frequent relapse and drug resistance in patients with hepatocellular carcinoma (HCC) can be attributed to the existence of tumor-initiating cells (TIC) within…”
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miR-130b Promotes CD133 + Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1 by Ma, Stephanie, Tang, Kwan Ho, Chan, Yuen Piu, Lee, Terence K., Kwan, Pak Shing, Castilho, Antonia, Ng, Irene, Man, Kwan, Wong, Nathalie, To, Ka-Fai, Zheng, Bo-Jian, Lai, Paul B.S., Lo, Chung Mau, Chan, Kwok Wah, Guan, Xin-Yuan

“…A novel paradigm in tumor biology suggests that cancer growth is driven by stem-like cells within a tumor, called tumor-initiating cells (TICs) or cancer stem…”
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Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3 by Wu, Chuan Xing, Xu, Aimin, Zhang, Cathy C, Olson, Peter, Chen, Lin, Lee, Terence K, Cheung, Tan To, Lo, Chung Mau, Wang, Xiao Qi

“…Aberrant activation of the Notch signaling pathway is implicated in many solid tumors, including hepatocellular carcinoma, indicating a potential use of Notch…”
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CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling by Tang, Kwan Ho, Ma, Stephanie, Lee, Terence K., Chan, Yuen Piu, Kwan, Pak Shing, Tong, Carol M., Ng, Irene O., Man, Kwan, To, Ka-Fai, Lai, Paul B., Lo, Chung-Mau, Guan, Xin-Yuan, Chan, Kwok Wah

“…A novel theory in the field of tumor biology postulates that cancer growth is driven by a population of stem‐like cells, called tumor‐initiating cells (TICs)…”
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SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma by Man, Ki-Fong, Zhou, Lei, Yu, Huajian, Lam, Ka-Hei, Cheng, Wei, Yu, Jun, Lee, Terence K., Yun, Jing-Ping, Guan, Xin-Yuan, Liu, Ming, Ma, Stephanie

“…Tumor lineage plasticity, considered a hallmark of cancer, denotes the phenomenon in which tumor cells co-opt developmental pathways to attain cellular…”
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PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation by Chan, Lok Hei, Zhou, Lei, Ng, Kai Yu, Wong, Tin Lok, Lee, Terence K., Sharma, Rakesh, Loong, Jane H., Ching, Yick Pang, Yuan, Yun-Fei, Xie, Dan, Lo, Chung Mau, Man, Kwan, Artegiani, Benedetta, Clevers, Hans, Yan, Helen H., Leung, Suet Yi, Richard, Stéphane, Guan, Xin-Yuan, Huen, Michael S.Y., Ma, Stephanie

“…Arginine methylation is a post-translational modification that plays pivotal roles in signal transduction and gene transcription during cell fate…”
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TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma by Ng, Kai-Yu, Chan, Lok-Hei, Chai, Stella, Tong, Man, Guan, Xin-Yuan, Lee, Nikki P, Yuan, Yunfei, Xie, Dan, Lee, Terence K, Dusetti, Nelson J, Carrier, Alice, Ma, Stephanie

“…Identifying critical factors involved in the metastatic progression of hepatocellular carcinoma (HCC) may offer important therapeutic opportunities. Here, we…”
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BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen-Resistant Breast Cancer by Gong Chun, Man Ellen PS, Tsoi Ho, Lee Terence KW, Lee, Paul, Sai-Ting, Ma, Lai-San, Wong, Mai-Yee, Luk, Rakha, Emad A, Green, Andrew R, Ellis, Ian O, Lam, Eric W-F, Kwok-Leung, Cheung, Ui-Soon, Khoo

“…Purpose: Adjuvant tamoxifen treatment revolutionized the management of estrogen receptor (ER)–positive breast cancers to prevent cancer recurrence; however,…”
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Twist Overexpression Correlates with Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition by LEE, Terence K, POON, Ronnie T. P, SHEUNG TAT FAN, YUEN, Anthony P, MING TAT LING, WEI KEI KWOK, XIANG HONG WANG, YONG CHUAN WONG, XINYUAN GUAN, MAN, Kwan, KING LOK CHAU

“…Purpose: Hepatocellular carcinoma (HCC) is a rapidly growing tumor associated with a high propensity for vascular invasion and metastasis…”
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ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma by Tong, Man, Fung, Tsun-Ming, Luk, Steve T., Ng, Kai-Yu, Lee, Terence K., Lin, Chi-Ho, Yam, Judy W., Chan, Kwok Wah, Ng, Fai, Zheng, Bo-Jian, Yuan, Yun-Fei, Xie, Dan, Lo, Chung-Mau, Man, Kwan, Guan, Xin-Yuan, Ma, Stephanie

“…Frequent tumor relapse in hepatocellular carcinoma (HCC) has been commonly attributed to the presence of residual cancer stem cells (CSCs) after conventional…”
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microRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2 by MA, Stephanie, YUEN PIU CHAN, PAK SHING KWAN, LEE, Terence K, MINGXIA YAN, KWAN HO TANG, MING TAT LING, VIELKIND, Juergen R, GUAN, Xin-Yuan, KWOK WAH CHAN

“…Expression of microRNA genes is profoundly altered in cancer but their role in the development of androgen-independent prostate cancer has received limited…”
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Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix Softness Induced Histone H3 Modifications by Ng, Kai‐Yu, Shea, Queenie T., Wong, Tin‐Lok, Luk, Steve T., Tong, Man, Lo, Chung‐Mau, Man, Kwan, Yun, Jing‐Ping, Guan, Xin‐Yuan, Lee, Terence K., Zheng, Yong‐Ping, Ma, Stephanie

“…The physical microenvironment is a critical mediator of tumor behavior. However, detailed biological and mechanistic insight is lacking. The present study…”
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Targeting cadherin‐17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma by Liu, Ling Xiao, Lee, Nikki P., Chan, Vivian W., Xue, Wen, Zender, Lars, Zhang, Chunsheng, Mao, Mao, Dai, Hongyue, Wang, Xiao Lin, Xu, Michelle Z., Lee, Terence K., Ng, Irene O., Chen, Yangchao, Kung, Hsiang‐fu, Lowe, Scott W., Poon, Ronnie T.P., Wang, Jian Hua, Luk, John M.

“…Hepatocellular carcinoma (HCC) is a lethal malignancy for which there are no effective therapies. To develop rational therapeutic approaches for treating this…”
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Ischemia‐reperfusion of small liver remnant promotes liver tumor growth and metastases—Activation of cell invasion and migration pathways by Man, Kwan, Ng, Kevin T., Lo, Chung Mau, Ho, Joanna W., Sun, Bai Shun, Sun, Chris K., Lee, Terence K., Poon, Ronnie T. P., Fan, Sheung Tat

“…Elucidating the mechanism of liver tumor growth and metastasis after hepatic ischemia‐reperfusion (I/R) injury of a small liver remnant will lay the foundation…”
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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers by Lee, Terence K, Murthy, Saravana R K, Cawley, Niamh X, Dhanvantari, Savita, Hewitt, Stephen M, Lou, Hong, Lau, Tracy, Ma, Stephanie, Huynh, Thanh, Wesley, Robert A, Ng, Irene O, Pacak, Karel, Poon, Ronnie T, Loh, Y Peng

“…Metastasis is a major cause of mortality in cancer patients. However, the mechanisms governing the metastatic process remain elusive, and few accurate…”
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Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial- mesenchymal transition by LEE, Terence K, MAN, Kwan, POON, Ronnie T. P, CHUNG MAU LO, YUEN, Anthony P, NG, Irene O, NG, Kevin T, LEONARD, Warren, SHEUNG TAT FAN

“…Poor prognosis of hepatocellular carcinoma (HCC) is associated with a high potential of vascular invasion and metastasis. Epithelial-mesenchymal transition…”
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Identification of a Novel Inhibitor of Differentiation-1 (ID-1) Binding Partner, Caveolin-1, and Its Role in Epithelial-Mesenchymal Transition and Resistance to Apoptosis in Prostate Cancer Cells by Zhang, Xiaomeng, Ling, Ming-Tat, Wang, Qi, Lau, Chi-Keung, Leung, Steve C.L., Lee, Terence K., Cheung, Annie L.M., Wong, Yong-Chuan, Wang, Xianghong

“…Recently, ID-1 (inhibitor of differentiation/DNA binding) is suggested as an oncogene and is reported to promote cell proliferation, invasion, and survival in…”
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Peri-Diaurated Naphthalene: Synthesis and Reactions of a New Class of Organogold(I) Complexes Containing Bridging, Dianionic Naphthalenediyl Ligands by Meyer, Nadine, Lehmann, Christian W, Lee, Terence K.-M, Rust, Jörg, Yam, Vivian W.-W, Mohr, Fabian

“…The dinuclear gold(I) compound [Au2(μ-C10H6){μ-Ph2P(CH2)2PPh2}] was prepared in high yield by the reaction of 1,8-bis(trimethylstannyl)naphthalene with…”
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