Search Results - "Lee, Tak C"

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate by Venturutti, Leandro, Teater, Matt, Zhai, Andrew, Chadburn, Amy, Babiker, Leena, Kim, Daleum, Béguelin, Wendy, Lee, Tak C., Kim, Youngjun, Chin, Christopher R., Yewdell, William T., Raught, Brian, Phillip, Jude M., Jiang, Yanwen, Staudt, Louis M., Green, Michael R., Chaudhuri, Jayanta, Elemento, Olivier, Farinha, Pedro, Weng, Andrew P., Nissen, Michael D., Steidl, Christian, Morin, Ryan D., Scott, David W., Privé, Gilbert G., Melnick, Ari M.

“…The most aggressive B cell lymphomas frequently manifest extranodal distribution and carry somatic mutations in the poorly characterized gene TBL1XR1. Here, we…”
Get full text

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML by Duy, Cihangir, Teater, Matt, Garrett-Bakelman, Francine E, Lee, Tak C, Meydan, Cem, Glass, Jacob L, Li, Meng, Hellmuth, Johannes C, Mohammad, Helai P, Smitheman, Kimberly N, Shih, Alan H, Abdel-Wahab, Omar, Tallman, Martin S, Guzman, Monica L, Muench, David, Grimes, H Leighton, Roboz, Gail J, Kruger, Ryan G, Creasy, Caretha L, Paietta, Elisabeth M, Levine, Ross L, Carroll, Martin, Melnick, Ari M

“…Disruption of epigenetic regulation is a hallmark of acute myeloid leukemia (AML), but epigenetic therapy is complicated by the complexity of the epigenome…”
Get more information

Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence by Duy, Cihangir, Li, Meng, Teater, Matt, Meydan, Cem, Garrett-Bakelman, Francine E, Lee, Tak C, Chin, Christopher R, Durmaz, Ceyda, Kawabata, Kimihito C, Dhimolea, Eugen, Mitsiades, Constantine S, Doehner, Hartmut, D'Andrea, Richard J, Becker, Michael W, Paietta, Elisabeth M, Mason, Christopher E, Carroll, Martin, Melnick, Ari M

“…Patients with acute myeloid leukemia (AML) frequently relapse after chemotherapy, yet the mechanism by which AML reemerges is not fully understood. Herein, we…”
Get more information

A Model for Dynamic Airline Seat Inventory Control with Multiple Seat Bookings by Lee, Tak C, Hersh, Marvin

“…It is common for the airlines to sell a pool of identical seats at different prices according to different booking classes to improve revenues in a very…”
Get full text

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2, and Correlates with More Aggressive AML by Samaraweera, Saumya E, Garrett-Bakelman, Francine E., Neelamraju, Yaseswini, Perugini, Michelle, Casolari, Debora A., Iarossi, Diana, Bray, Sarah C, Sheridan, Caroline, Lee, Tak C, Tiong, Ing Soo, Danner, Silke, Cummings, Nik, Guzman, Monica L., Roboz, Gail J., To, Luen Bik, Wei, Andrew, Mason, Christopher E., Park, Christopher Y., Levine, Ross L., Carroll, Martin, Becker, Michael W., Lewis, Ian D, Melnick, Ari, D'Andrea, Richard

“…We have previously reported that hypermethylationof the GADD45A promoter (GADD45AmeHI) occurs frequently in AML at a specific CpG residue (CpG1) and associates…”
Get full text

Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia by Rapaport, Franck, de Massy, Marc Robert, al Hinai, Adil, Sanders, Mathijs A., Hricik, Todd, Sheridan, Caroline, Lee, Tak C, Neelamraju, Yaseswini, Patel, Jay, Chung, Stephen S., Becker, Michael W., Lewis, Ian D, D'Andrea, Richard, Bullinger, Lars, Döhner, Konstanze, Döhner, Hartmut, Guzman, Monica L., Roboz, Gail J., Carroll, Martin, Park, Christopher Y., Mason, Christopher E., Melnick, Ari, Levine, Ross L., Valk, Peter J.M., Garrett-Bakelman, Francine E.

“…Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. Unfortunately, a significant proportion of patients relapse after responding…”
Get full text

Cooperative Gene Repression By DNA Methylation and LSD1-Mediated Enhancer Inactivation in Acute Myeloid Leukemia by Duy, Cihangir, Teater, Matt, Garrett-Bakelman, Francine E., Lee, Tak C, Meydan, Cem, Glass, Jacob Lowell, Li, Meng, Mohammad, Helai, Smitheman, Kimberly, Shih, Alan H., Abdel-Wahab, Omar, Paietta, Elisabeth, Tallman, Martin S., Guzman, Monica L., Kruger, Ryan G., Creasy, Caretha L., Levine, Ross L., Carroll, Martin, Melnick, Ari

“…Epigenetic silencing of tumor suppressor genes, mediated by aberrant DNA hypermethylation and repressive histone modifications, is a hallmark of acute myeloid…”
Get full text

Decomposition of linear programs using parallel computation by HO, K, LEE, T. C, SUNDARRAJ, R. P

“…This paper describes DECOMPAR: an implementation of the Dantzig-Wolfe decomposition algorithm for block-angular linear programs using parallel processing of…”
Get full text