Search Results - "Lee, Tae Sup"
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Imageable Antigen-Presenting Gold Nanoparticle Vaccines for Effective Cancer Immunotherapy In Vivo
Published in Angewandte Chemie International Edition (27-08-2012)“…Delivery tracking: Goldnanoparticles (AuNPs) were functionalized with a red fluorescent protein (RFP, pink shapes in picture) as model antigen and an…”
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A Bioluminogenic Probe for Monitoring Tyrosinase Activity
Published in Chemistry, an Asian journal (16-02-2017)“…A bioluminogenic probe based on luciferin was designed and synthesized to monitor tyrosinase activity. This probe was efficient in assessing tyrosinase…”
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Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma
Published in Molecular cancer therapeutics (01-09-2007)“…Hypoxia stimulates hepatocellular carcinoma (HCC) cell growth via hexokinase (HK) II induction, and alternatively, HK II inhibition induces apoptosis by…”
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4
Facile metabolic glycan labeling strategy for exosome tracking
Published in Biochimica et biophysica acta. General subjects (01-05-2018)“…Exosomes are nano-sized vesicles derived from the fusion of multivesicular bodies with the surrounding plasma membrane. Exosomes have various diagnostic and…”
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Anti-EGF Receptor Aptamer-Guided Co-Delivery of Anti-Cancer siRNAs and Quantum Dots for Theranostics of Triple-Negative Breast Cancer
Published in Theranostics (01-01-2019)“…Many aptamers have been evaluated for their ability as drug delivery vehicles to target ligands, and a variety of small interfering RNAs (siRNAs) have been…”
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6
Amphiphilic polymer-coated hybrid nanoparticles as CT/MRI dual contrast agents
Published in Nanotechnology (15-04-2011)“…We describe hybrid nanoparticles, composed of iron oxide and gold nanoparticles, as potential dual contrast agents for both computed tomography (CT) and…”
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Construction, Affinity Maturation, and Biological Characterization of an Anti-tumor-associated Glycoprotein-72 Humanized Antibody
Published in The Journal of biological chemistry (17-03-2006)“…The tumor-associated glycoprotein (TAG)-72 is expressed in the majority of human adenocarcinomas but is rarely expressed in most normal tissues, which makes it…”
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Cancer-targeted Nucleic Acid Delivery and Quantum Dot Imaging Using EGF Receptor Aptamer-conjugated Lipid Nanoparticles
Published in Scientific reports (25-08-2017)“…Co-application of fluorescent quantum dot nanocrystals and therapeutics has recently become a promising theranostic methodology for cancer treatment. We…”
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Radiopharmaceuticals for Skeletal Muscle PET Imaging
Published in International journal of molecular sciences (01-05-2024)“…The skeletal muscles account for approximately 40% of the body weight and are crucial in movement, nutrient absorption, and energy metabolism. Muscle loss and…”
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Development of PET Radioisotope Copper-64-Labeled Theranostic Immunoliposomes for EGFR Overexpressing Cancer-Targeted Therapy and Imaging
Published in International journal of molecular sciences (01-02-2024)“…Combining standard surgical procedures with personalized chemotherapy and the continuous monitoring of cancer progression is necessary for effective NSCLC…”
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800 nm near-infrared light-excitable intense green-emitting Li(Gd,Y)F4:Yb,Er-based core/shell/shell upconversion nanophosphors for efficient liver cancer cell imaging
Published in Materials & design (01-10-2020)“…In this study, novel 800 nm-excitable and highly intense green-emitting non-NaY(Gd)F4-based core/shell/shell (CSS) upconversion nanophosphors (UCNPs) are…”
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Saengmaeksan, a traditional polyherbal formulation containing Panax ginseng, improves energy metabolism during exercise
Published in PloS one (29-01-2024)“…Saengmaeksan (SMS), a representative oriental medicine that contains Panax ginseng Meyer, Liriope muscari, and Schisandra chinensis (1:2:1), is used to improve…”
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13
CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer
Published in Cell death & disease (07-01-2021)“…Lung cancer is one of the most common reasons for cancer-induced mortality across the globe, despite major advancements in the treatment strategies including…”
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14
An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage
Published in Nature communications (02-06-2021)“…Targeting the molecular pathways underlying the cardiotoxicity associated with thoracic irradiation and doxorubicin (Dox) could reduce the morbidity and…”
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In Vivo Evaluation of 68Ga-Labeled NOTA-EGFRvIII Aptamer in EGFRvIII-Positive Glioblastoma Xenografted Model
Published in Pharmaceutics (16-06-2024)“…EGFRvIII is expressed only in tumor cells and strongly in glioblastoma and is considered a promising target in cancer diagnosis and therapy. Aptamers are…”
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Tumor-Targeted Erythrocyte Membrane Nanoparticles for Theranostics of Triple-Negative Breast Cancer
Published in Pharmaceutics (20-01-2023)“…Triple-negative breast cancer (TNBC) cells do not contain various receptors for targeted treatment, a reason behind the poor prognosis of this disease. In this…”
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Integrin alpha 6: a novel therapeutic target in esophageal squamous cell carcinoma
Published in International journal of oncology (01-11-2013)“…Esophageal squamous cell carcinoma (ESCC), the most common subtype of esophageal cancer in East Asian countries, is a devastating disease characterized by…”
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Innovations in Nuclear Medicine Imaging for Reactive Oxygen Species: Applications and Radiopharmaceuticals
Published in Antioxidants (17-10-2024)“…Reactive oxygen species (ROS) are generated during normal cellular energy production and play a critical role in maintaining cellular function. However,…”
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Combination of anti-L1 cell adhesion molecule antibody and gemcitabine or cisplatin improves the therapeutic response of intrahepatic cholangiocarcinoma
Published in PloS one (06-02-2017)“…Cholangiocarcinoma has a poor prognosis and is refractory to conventional chemotherapy and radiation therapy. Improving survival of patients with advanced…”
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In vivo tissue pharmacokinetics of ERBB2‐specific binding oligonucleotide‐based drugs by PET imaging
Published in Clinical and translational science (01-07-2023)“…Although aptamers have shown excellent target specificity in preclinical and clinical studies either by themselves or as aptamer‐drug conjugates, their in vivo…”
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