Search Results - "Lee, Sueun"
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Temozolomide promotes matrix metalloproteinase 9 expression through p38 MAPK and JNK pathways in glioblastoma cells
Published in Scientific reports (21-06-2024)“…Glioblastoma (GBM) is a highly aggressive and deadly brain cancer. Temozolomide (TMZ) is the standard chemotherapeutic agent for GBM, but the majority of…”
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Hyperbranched Double Hydrophilic Block Copolymer Micelles of Poly(ethylene oxide) and Polyglycerol for pH-Responsive Drug Delivery
Published in Biomacromolecules (09-04-2012)“…We report the synthesis of a well-defined hyperbranched double hydrophilic block copolymer of poly(ethylene oxide)-hyperbranched-polyglycerol (PEO-hb-PG) to…”
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Behavioral Tasks Evaluating Schizophrenia-like Symptoms in Animal Models: A Recent Update
Published in Current neuropharmacology (01-01-2021)“…Background: Schizophrenia is a serious mental illness that affects more than 21 million people worldwide. Both genetics and the environment play a role in its…”
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Neuroprotective Effect of Protaetia brevitarsis seulensis ' Water Extract on Trimethyltin-Induced Seizures and Hippocampal Neurodegeneration
Published in International journal of molecular sciences (12-01-2021)“…This study aimed to investigate whether the (PB)' water extract (PBWE) ameliorates trimethyltin (TMT)-induced seizures and hippocampal neurodegeneration. To…”
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Integrated Genome-Wide Analysis of DNA Methylation and Gene Expression in the Hippocampi of 5xFAD Alzheimer's Disease Mouse Model
Published in Journal of integrative neuroscience (24-07-2024)“…DNA methylation forms 5-methylcytosine and its regulation in the hippocampus is critical for learning and memory. Indeed, dysregulation of DNA methylation is…”
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Transcriptome Profiling Reveals Novel Candidate Genes Related to Hippocampal Dysfunction in SREBP-1c Knockout Mice
Published in International journal of molecular sciences (10-06-2020)“…Lipid homeostasis is an important component of brain function, and its disturbance causes several neurological disorders, such as Huntington's, Alzheimer's,…”
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Brain-derived neurotropic factor and GABAergic transmission in neurodegeneration and neuroregeneration
Published in Neural regeneration research (01-10-2017)“…Neurotoxicity induced by stress,radiation,chemicals,or metabolic diseases,is commonly associated with excitotoxicity,oxidative stress,and neuroinflammation.The…”
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Silk Fibroin Promotes the Regeneration of Pancreatic β-Cells in the C57BL/KsJ-Leprdb/db Mouse
Published in Molecules (Basel, Switzerland) (17-07-2020)“…Diabetes mellitus is a chronic metabolic disease, and its progression leads to serious complications. Although various novel therapeutic approaches for…”
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SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice
Published in International journal of molecular sciences (05-06-2021)“…Changes in structural and functional neuroplasticity have been implicated in various neurological disorders. Sterol regulatory element-binding protein…”
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One-Pot Synthesis of Linear-Hyperbranched Amphiphilic Block Copolymers Based on Polyglycerol Derivatives and Their Micelles
Published in Biomacromolecules (08-07-2013)“…This paper describes the one-pot synthesis of a polyglycidol (PG)-based polymer, poly(ethoxyethyl glycidyl ether) (PEEGE)-b-[hyperbranched polyglycerol…”
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Silk fibroin promotes the regeneration of pancreatic β-cells in the C57BL/KsJ-Leprdb/db mouse
Published in Integrative medicine research (2020)Get full text
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Protective effects of an aqueous extract of Protaetia brevitarsis seulensis larvae in an ovalbumin-induced murine model of asthma
Published in Food and agricultural immunology (01-12-2023)“…Asthma is a disease-related allergic response characterized by the accumulation of inflammatory cells in airway tissue. Protaetia brevitarsis seulensis larvae…”
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3-Pentylcatechol, a Non-Allergenic Urushiol Derivative, Displays Anti-Helicobacter pylori Activity In Vivo
Published in Pharmaceuticals (Basel, Switzerland) (13-11-2020)“…We previously reported that 3-pentylcatechol (PC), a synthetic non-allergenic urushiol derivative, inhibited the growth of Helicobacter pylori in an in vitro…”
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Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus
Published in International journal of developmental neuroscience (01-11-2014)“…•Hippocampal BDNF-encoding mRNA level increased during postnatal development.•BDNF exon transcripts were differentially regulated during hippocampal…”
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Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus
Published in International journal of developmental neuroscience (01-12-2015)“…•GABA is involved in neurogenesis, neuronal migration, plasticity, and neuronal networking in CNS.•Each GABAR subunits altered differently during postnatal…”
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Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain
Published in Molecules and cells (2018)“…Crosstalk between G-protein signaling and glutamatergic transmission within the brain reward circuits is critical for long-term emotional effects (depression…”
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Neuroprotective effect of Geijigadaehwang-tang against trimethyltin-induced hippocampal neurodegeneration: An in vitro and in vivo study
Published in Journal of ethnopharmacology (05-10-2022)“…Patients with dementia are diagnosed with deficiency patterns and interior patterns in traditional Chinese medicine due to decreased physical strength, mental…”
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Abstract 5407: Temozolomide promotes matrix metalloproteinase 9 expression through p38 MAPK and JNK pathways in glioblastoma cells
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Glioblastoma multiforme (GBM) is a highly aggressive and deadly brain cancer. Temozolomide (TMZ) is the standard chemotherapeutic agent for GBM, but…”
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Gekko gecko extract attenuates airway inflammation and mucus hypersecretion in a murine model of ovalbumin-induced asthma
Published in Journal of ethnopharmacology (10-01-2022)“…Gekko gecko is used as a traditional medicine for various diseases including respiratory disorders in northeast Asian countries, mainly Korea, Japan, and…”
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