Coexistence of Malakoplakia and Papillary Urothelial Carcinoma of the Urinary Bladder

Malakoplakia is a rare granulomatous disease that commonly involves the genitourinary tract, with the urinary bladder being the most frequently affected site. Grossly, malakoplakia can present as soft yellow plaques, nodules, bladder mass, or even without any visible lesion. In this article, we pres...

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Bibliographic Details
Published in:	International journal of surgical pathology Vol. 23; no. 7; pp. 575 - 578
Main Authors:	Lee, Song Liang Joshua, Teo, Jin Kiat, Lim, Sey Kiat Terence, Salkade, Hema Parag, Mancer, Kent
Format:	Journal Article
Language:	English
Published:	Los Angeles, CA SAGE Publications 01-10-2015
Subjects:	Aged Carcinoma, Papillary - complications Carcinoma, Papillary - pathology Carcinoma, Transitional Cell - complications Carcinoma, Transitional Cell - pathology Female Humans Malacoplakia - complications Malacoplakia - pathology Urinary Bladder Neoplasms - complications Urinary Bladder Neoplasms - pathology Urothelium - pathology papillary urothelial carcinoma urinary bladder malakoplakia
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Summary:	Malakoplakia is a rare granulomatous disease that commonly involves the genitourinary tract, with the urinary bladder being the most frequently affected site. Grossly, malakoplakia can present as soft yellow plaques, nodules, bladder mass, or even without any visible lesion. In this article, we present a 74-year-old female with a background of hypertension, hyperlipidemia, and poorly controlled diabetes who presented with sepsis of unknown origin. During the course of the investigation of the source of her sepsis, an incidental bladder tumor was discovered. She subsequently underwent transurethral resection of the bladder tumor. Histology revealed ordinary low-grade papillary urothelial carcinoma that had small colonies of malakoplakia that appeared to have developed secondary to the tumor and presented concurrently. We seek to demonstrate the rare association of papillary urothelial carcinoma and malakoplakia.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1066-8969 1940-2465
DOI:	10.1177/1066896915595464