Search Results - "Lee, Simon Ming‐yuen"

“Ice and Fire” Supramolecular Cell‐Conjugation Drug Delivery Platform for Deep Tumor Ablation and Boosted Antitumor Immunity by Xu, Meng, Zha, Haidong, Chen, Jiamao, Lee, Simon Ming‐Yuen, Wang, Qi, Wang, Ruibing, Zheng, Ying

“…Cancer recurrence and metastasis are two major challenges in the current clinical therapy. In this work, a novel diketopyrrolopyrrole‐based photothermal…”
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Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism by Shen, Shengnan, Liao, Qiwen, Liu, Jingxin, Pan, Ruile, Lee, Simon Ming‐Yuen, Lin, Ligen

“…Background Muscle atrophy and weakness are adverse effects of high dose or the sustained usage of glucocorticoids. Loss of mitochondria and degradation of…”
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Particle Integrity and Size Effect on the Journey of Polymeric Nanocarriers in Zebrafish Model and the Correlation with Mice by Tao, Jinsong, Wei, Zhengjie, Xu, Meng, Xi, Long, Cheng, Yaxin, Lee, Simon Ming‐Yuen, Ge, Wei, Zheng, Ying

“…Polymeric nanocarriers have high biocompatibility for potential drug delivery applications. After entering bloodstream, nanocarriers will circulate, interact…”
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The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing by Martinez Barrio, Alvaro, Lamichhaney, Sangeet, Fan, Guangyi, Rafati, Nima, Pettersson, Mats, Zhang, He, Dainat, Jacques, Ekman, Diana, Höppner, Marc, Jern, Patric, Martin, Marcel, Nystedt, Björn, Liu, Xin, Chen, Wenbin, Liang, Xinming, Shi, Chengcheng, Fu, Yuanyuan, Ma, Kailong, Zhan, Xiao, Feng, Chungang, Gustafson, Ulla, Rubin, Carl-Johan, Sällman Almén, Markus, Blass, Martina, Casini, Michele, Folkvord, Arild, Laikre, Linda, Ryman, Nils, Ming-Yuen Lee, Simon, Xu, Xun, Andersson, Leif

“…Ecological adaptation is of major relevance to speciation and sustainable population management, but the underlying genetic factors are typically hard to study…”
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Garcinone E suppresses breast cancer growth and metastasis by modulating tumor-associated macrophages polarization via STAT6 signaling by Nie, Xin, Fu, Li, Cheng, Yanfen, Wu, Xiaoping, Lv, Kongpeng, Li, Renkai, Wu, Yihan, Leung, George Pak-Heng, Fu, Chaomei, Lee, Simon Ming-Yuen, Seto, Sai-Wang, Zhang, Jinming, Li, Jingjing

“…Cancer metastasis remains the most common cause of death in breast cancer patients. Tumor-associated macrophages (TAMs) are a novel therapeutic target for the…”
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A chromosome‐level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birth by He, Yan, Chang, Yue, Bao, Lisui, Yu, Mengjun, Li, Rui, Niu, Jingjing, Fan, Guangyi, Song, Weihao, Seim, Inge, Qin, Yating, Li, Xuemei, Liu, Jinxiang, Kong, Xiangfu, Peng, Meiting, Sun, Minmin, Wang, Mengya, Qu, Jiangbo, Wang, Xuangang, Liu, Xiaobing, Wu, Xiaolong, Zhao, Xi, Wang, Xuliang, Zhang, Yaolei, Guo, Jiao, Liu, Yang, Liu, Kaiqiang, Wang, Yilin, Zhang, He, Liu, Longqi, Wang, Mingyue, Yu, Haiyang, Wang, Xubo, Cheng, Jie, Wang, Zhigang, Xu, Xun, Wang, Jian, Yang, Huanming, Lee, Simon Ming‐Yuen, Liu, Xin, Zhang, Quanqi, Qi, Jie

“…The black rockfish (Sebastes schlegelii) is a teleost in which eggs are fertilized internally and retained in the maternal reproductive system, where they…”
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6‐benzylaminopurine causes endothelial dysfunctions to human umbilical vein endothelial cells and exacerbates atorvastatin‐induced cerebral hemorrhage in zebrafish by Gong, Guiyi, Kam, Hiotong, Bai, Yubin, Cheang, Wai san, Wu, Shuilong, Cheng, Xiaoning, Giesy, John P., Lee, Simon Ming‐yuen

“…6‐benzylaminopurine (6‐BA), a multifunctional plant growth regulator, which is frequently used worldwide to improve qualities of various crops, is an important…”
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A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells by Zhang, Ying, Deng, Hongkuan, Zhou, Hefeng, Lu, Yucong, Shan, Luchen, Lee, Simon Ming‐Yuen, Cui, Guozhen

“…Doxorubicin (Dox) is a well‐known chemotherapeutic agent used in the treatment of various cancers. However, Dox‐induced cardiotoxicity limits its further…”
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Genome guided investigation of antibiotics producing actinomycetales strain isolated from a Macau mangrove ecosystem by Hu, Dini, Chen, Yan, Sun, Chenghang, Jin, Tao, Fan, Guangyi, Liao, Qiwen, Mok, Kai Meng, Lee, Ming-Yuen Simon

“…Actinomycetes are a heterogeneous group of gram positive filamentous bacteria that have been found to produce a wide range of valuable bioactive secondary…”
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ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders by Chong, Cheong-Meng, Ai, Nana, Lee, Simon Ming-Yuen

“…Rho-associated protein kinase (ROCK) is a serine-threonine kinase originally identified as a crucial regulator of actin cytoskeleton. Recent studies have…”
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Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation by Li, Chuwen, Chen, Tongkai, Zhou, Hefeng, Zhang, Chao, Feng, Yu, Tang, Fan, Hoi, Maggie Pui-Man, He, Chengwei, Zheng, Ying, Lee, Simon Ming-Yuen

“…Background/Aims: In the present study, we investigated whether schisantherin A (StA) had anti-inflammatory effects under neuroinflammatory conditions. Methods:…”
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Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat by Yan, Fenggen, Chen, Dacan, Yu, Hon Ho, Lee, Simon Ming-Yuen, Choi, I. Cheong, Ren, Zhitao, Cui, Guozhen, Wang, Tao, Lan, Qingping, Yang, Binrui, Chen, Yan, Feng, Yu, Leung, George Pak-Heng

“…In parallel with the prevalence metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in most…”
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Controllable synthesis of functional nanoparticles by microfluidic platforms for biomedical applications - a review by Ma, Junping, Lee, Simon Ming-Yuen, Yi, Changqing, Li, Cheuk-Wing

“…Nanoparticles have drawn significant attention in biomedicine due to their unique optical, thermal, magnetic and electrical properties which are highly related…”
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Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4′-trimethoxystilbene by Deng, Yan-Hui, Alex, Deepa, Huang, He-Qing, Wang, Nan, Yu, Nan, Wang, Yi-Tao, Leung, George P.H, Lee, Simon Ming-Yuen

“…Resveratrol (RSV) has been shown to have anti-inflammatory activity and to have a protective role against atherosclerosis. Here it is shown, for the first…”
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The high‐quality genome of Brassica napus cultivar ‘ZS11’ reveals the introgression history in semi‐winter morphotype by Sun, Fengming, Fan, Guangyi, Hu, Qiong, Zhou, Yongming, Guan, Mei, Tong, Chaobo, Li, Jiana, Du, Dezhi, Qi, Cunkou, Jiang, Liangcai, Liu, Weiqing, Huang, Shunmou, Chen, Wenbin, Yu, Jingyin, Mei, Desheng, Meng, Jinling, Zeng, Peng, Shi, Jiaqin, Liu, Kede, Wang, Xi, Wang, Xinfa, Long, Yan, Liang, Xinming, Hu, Zhiyong, Huang, Guodong, Dong, Caihua, Zhang, He, Li, Jun, Zhang, Yaolei, Li, Liangwei, Shi, Chengcheng, Wang, Jiahao, Lee, Simon Ming‐Yuen, Guan, Chunyun, Xu, Xun, Liu, Shengyi, Liu, Xin, Chalhoub, Boulos, Hua, Wei, Wang, Hanzhong

“…Summary Allotetraploid oilseed rape (Brassica napus L.) is an agriculturally important crop. Cultivation and breeding of B. napus by humans has resulted in…”
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Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase by Shen, Shengnan, Liao, Qiwen, Feng, Yu, Liu, Jingxin, Pan, Ruile, Lee, Simon Ming-Yuen, Lin, Ligen

“…•Myricanol from the barks of Chinese bayberry was identified as an AMPK activator.•Myricanol inhibited adipogenesis in the initial stage of adipocytes…”
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Synergistic Effects of Chuanxiong-Chishao Herb-Pair on Promoting Angiogenesis at Network Pharmacological and Pharmacodynamic Levels by Wang, Yan, Guo, Gang, Yang, Bin-rui, Xin, Qi-qi, Liao, Qi-wen, Lee, Simon Ming-Yuen, Hu, Yuan-jia, Chen, Ke-ji, Cong, Wei-hong

“…Objective： To investigate the synergistic effects of Chuanxiong-Chishao herb-pair （CCHP） on promoting angiogenesis in silico and in vivo. Methods： The…”
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Evaluation in zebrafish model of the toxicity of rhodamine B‐conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics by Chan, Judy Yuet‐Wa, Zhou, Hefeng, Kwan, Yiu Wa, Chan, Shun Wan, Radis‐Baptista, Gandhi, Lee, Simon Ming‐Yuen

“…Crotamine is defensin‐like cationic peptide from rattlesnake venom that possesses anticancer, antimicrobial, and antifungal properties. Despite these promising…”
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Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax) by Lamichhaney, Sangeet, Fan, Guangyi, Widemo, Fredrik, Gunnarsson, Ulrika, Thalmann, Doreen Schwochow, Hoeppner, Marc P, Kerje, Susanne, Gustafson, Ulla, Shi, Chengcheng, Zhang, He, Chen, Wenbin, Liang, Xinming, Huang, Leihuan, Wang, Jiahao, Liang, Enjing, Wu, Qiong, Lee, Simon Ming-Yuen, Xu, Xun, Höglund, Jacob, Liu, Xin, Andersson, Leif

“…Leif Andersson and colleagues report the genome sequence of the ruff, a bird species with three male morphs with different reproductive strategies. Satellite…”
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Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside by Bian, Yaqi, Zhao, Chen, Lee, Simon Ming-Yuen

“…The increasing morbidity rates of brain disorders and conditions such as anxiety, depression, Alzheimer’s disease, and Parkinson’s disease have become a severe…”
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