Search Results - "Lee, Pa Reum"
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Involvement of cannabinoid type 1 receptor in fasting-induced analgesia
Published in Molecular pain (2020)“…The endocannabinoid system (ECS) is known to modulate not only food intake but also pain, especially via the cannabinoid type 1 receptor (CB1R) expressed…”
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Alpha 2 adrenoceptor agonist guanabenz directly inhibits hyperpolarization-activated, cyclic nucleotide-modulated (HCN) channels in mesencephalic trigeminal nucleus neurons
Published in European journal of pharmacology (05-07-2019)“…Alpha 2 (α2-) adrenoceptor agonists, such as clonidine or dexmedetomidine, have been found to inhibit hyperpolarization-activated, cyclic nucleotide-modulated…”
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3
Piezo1 mediates mechanical signals in TRPV1‐positive nociceptors in mice
Published in Acta Physiologica (01-11-2024)“…Aim This investigation addresses Piezo1's expression and mechanistic role in dorsal root ganglion (DRG) neurons and delineates its participation in mechanical…”
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Peripheral GABAA receptor-mediated signaling facilitates persistent inflammatory hypersensitivity
Published in Neuropharmacology (01-06-2018)“…Unlike in the central nervous system (CNS), in the adult peripheral nervous system (PNS), activation of GABAA receptors (GABAAR) is excitatory because of the…”
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TRANSCRIPTIONAL PROFILING OF DENTAL SENSORY AND PROPRIOCEPTIVE TRIGEMINAL NEURONS USING SINGLE-CELL RNA-SEQUENCING
Published in IBRO neuroscience reports (01-10-2023)Get full text
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6
The analgesic effect of refeeding on acute and chronic inflammatory pain
Published in Scientific reports (14-11-2019)“…Pain is susceptible to various cognitive factors. Suppression of pain by hunger is well known, but the effect of food intake after fasting (i.e. refeeding) on…”
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Transcriptional profiling of dental sensory and proprioceptive trigeminal neurons using single-cell RNA sequencing
Published in International journal of oral science (25-09-2023)“…Dental primary afferent (DPA) neurons and proprioceptive mesencephalic trigeminal nucleus (MTN) neurons, located in the trigeminal ganglion and the brainstem,…”
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PIEZO1 MEDIATES INFLAMMATORY TACTILE PAIN SENSITIVITY IN NOCICEPTORS
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons
Published in The Korean journal of physiology & pharmacology (31-03-2018)“…Recent studies have provided several lines of evidence that peripheral administration of oxytocin induces analgesia in human and rodents. However, the exact…”
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Mitochondrial Reactive Oxygen Species Elicit Acute and Chronic Itch via Transient Receptor Potential Canonical 3 Activation in Mice
Published in Neuroscience bulletin (01-04-2022)“…Mitochondrial reactive oxygen species (mROS) that are overproduced by mitochondrial dysfunction are linked to pathological conditions including sensory…”
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11
Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons
Published in The Korean journal of physiology & pharmacology (01-03-2018)“…Recent studies have provided several lines of evidence that peripheral administration of oxytocin induces analgesia in human and rodents. However, the exact…”
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12
Acute inflammation reveals GABA A receptor-mediated nociception in mouse dorsal root ganglion neurons via PGE 2 receptor 4 signaling
Published in Physiological reports (01-04-2017)“…Gamma-aminobutyric acid (GABA) depolarizes dorsal root ganglia (DRG) primary afferent neurons through activation of Cl permeable GABA receptors but the…”
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13
Expression patterns of Piezo1 in the developing mouse forebrain
Published in Brain Structure and Function (01-04-2024)“…Malformation during cortical development can disrupt the balance of excitatory and inhibitory neural circuits, contributing to various psychiatric and…”
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14
Peripheral GABA A receptor-mediated signaling facilitates persistent inflammatory hypersensitivity
Published in Neuropharmacology (01-06-2018)“…Unlike in the central nervous system (CNS), in the adult peripheral nervous system (PNS), activation of GABA receptors (GABA R) is excitatory because of the…”
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15
Upregulation of Toll-like Receptor 2 in Dental Primary Afferents Following Pulp Injury
Published in Experimental neurobiology (31-10-2021)“…Pulpitis (toothache) is a painful inflammation of the dental pulp and is a prevalent problem throughout the world. This pulpal inflammation occurs in the cells…”
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Acute inflammation reveals GABAA receptor‐mediated nociception in mouse dorsal root ganglion neurons via PGE2 receptor 4 signaling
Published in Physiological reports (01-04-2017)“…Gamma‐aminobutyric acid (GABA) depolarizes dorsal root ganglia (DRG) primary afferent neurons through activation of Cl− permeable GABAA receptors but the…”
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Acute inflammation reveals GABA sub(A) receptor-mediated nociception in mouse dorsal root ganglion neurons via PGE sub(2) receptor 4 signaling
Published in Physiological reports (01-04-2017)“…Gamma-aminobutyric acid (GABA) depolarizes dorsal root ganglia (DRG) primary afferent neurons through activation of Cl super(-) permeable GABA sub(A) receptors…”
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18
Acute inflammation reveals GABAA receptor‐mediated nociception in mouse dorsal root ganglion neurons via PGE 2 receptor 4 signaling
Published in Physiological reports (24-04-2017)“…Gamma‐aminobutyric acid ( GABA ) depolarizes dorsal root ganglia ( DRG ) primary afferent neurons through activation of Cl − permeable GABA A receptors but the…”
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19
Endocannabinoid receptor 1 contributes to fasting-induced analgesia
Published in IBRO reports (01-09-2019)Get full text
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