Search Results - "Lee, Moon Yong"

Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases by Kim, Ye-Ryung, Lee, Eun-Ji, Shin, Kyong-Oh, Kim, Min Hee, Pewzner-Jung, Yael, Lee, Yong-Moon, Park, Joo-Won, Futerman, Anthony H., Park, Woo-Jae

“…The endoplasmic reticulum (ER) is not only important for protein synthesis and folding but is also crucial for lipid synthesis and metabolism. In the current…”
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Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed by Ryu, Hwa Sun, Jeong, JiYeon, Lee, Chun Mong, Lee, Kwang Sik, Lee, Jung-No, Park, Sung-Min, Lee, Yong-Moon

“…Hair loss by excessive stress from work and lifestyle changes has become a growing concern, particularly among young individuals. However, most drugs for…”
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Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate by Venkataraman, Krishnan, Lee, Yong-Moon, Michaud, Jason, Thangada, Shobha, Ai, Youxi, Bonkovsky, Herbert L, Parikh, Nehal S, Habrukowich, Cheryl, Hla, Timothy

“…Sphingosine 1-phosphate (S1P), an abundant lipid mediator in plasma, regulates vascular and immune cells by activating S1P receptors. In this report, we…”
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Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression by McHugh, Donal, Caduff, Nicole, Barros, Mario Henrique M., Rämer, Patrick C., Raykova, Ana, Murer, Anita, Landtwing, Vanessa, Quast, Isaak, Styles, Christine T., Spohn, Michael, Fowotade, Adeola, Delecluse, Henri-Jacques, Papoudou-Bai, Alexandra, Lee, Yong-Moon, Kim, Jin-Man, Middeldorp, Jaap, Schulz, Thomas F., Cesarman, Ethel, Zbinden, Andrea, Capaul, Riccarda, White, Robert E., Allday, Martin J., Niedobitek, Gerald, Blackbourn, David J., Grundhoff, Adam, Münz, Christian

“…The human tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) establish persistent infections in B cells. KSHV is linked to…”
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Identification of biomarkers on kidney failure by Raman spectroscopy by Gulyamov, Shokhid, Shamshiddinova, Maftuna, Bae, Woo‐Hyun, Park, Yun Cheol, Kim, Hyo Jin, Cho, Won‐Bo, Lee, Yong‐Moon

“…Chronic kidney disease (CKD) is a global health problem. Our study employed Raman spectroscopy for the first time to analyze potential biomarker such as…”
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ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex by Park, Kyungho, Ikushiro, Hiroko, Seo, Ho Seong, Shin, Kyong-Oh, Kim, Young il, Kim, Jong Youl, Lee, Yong-Moon, Yano, Takato, Holleran, Walter M., Elias, Peter, Uchida, Yoshikazu

“…We recently identified a previously unidentified sphingosine-1-phosphate (S1P) signaling mechanism that stimulates production of a key innate immune element,…”
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A Dansyl-Modified Sphingosine Kinase Inhibitor DPF-543 Enhanced De Novo Ceramide Generation by Shamshiddinova, Maftuna, Gulyamov, Shokhid, Kim, Hee-Jung, Jung, Seo-Hyeon, Baek, Dong-Jae, Lee, Yong-Moon

“…Sphingosine-1-phosphate (S1P) synthesized by sphingosine kinase (SPHK) is a signaling molecule, involved in cell proliferation, growth, differentiation, and…”
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Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice by Choi, Kyeong-Mi, Lee, Youn-Sun, Kim, Wonkyun, Kim, Seung Jung, Shin, Kyong-Oh, Yu, Ji-Yeon, Lee, Mi Kyeong, Lee, Yong-Moon, Hong, Jin Tae, Yun, Yeo-Pyo, Yoo, Hwan-Soo

“…Obesity is associated with metabolic disorders. Sulforaphane, an isothiocyanate, inhibits adipogenesis and the occurrence of cardiovascular disease. In this…”
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Predicting Carcinogenic Mechanisms of Non-Genotoxic Carcinogens via Combined Analysis of Global DNA Methylation and In Vitro Cell Transformation by Hwang, Sung-Hee, Yeom, Hojin, Han, Byeal-I, Ham, Byung-Joo, Lee, Yong-Moon, Han, Mi-Ryung, Lee, Michael

“…An in vitro cell transformation assay (CTA) is useful for the detection of non-genotoxic carcinogens (NGTXCs); however, it does not provide information on…”
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Genome‐wide DNA methylation changes in transformed foci induced by nongenotoxic carcinogens by Hwang, Sung‐Hee, Yeom, Hojin, Eom, Seong Yun, Lee, Yong‐Moon, Lee, Michael

“…In vitro cell transformation assays (CTA) have been proposed as a method to identify possible nongenotoxic carcinogens. However, the current protocols do not…”
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Sulforaphane Inhibits Mitotic Clonal Expansion During Adipogenesis Through Cell Cycle Arrest by Choi, Kyeong‐Mi, Lee, Youn‐Sun, Sin, Dong‐Mi, Lee, Seunghyun, Lee, Mi Kyeong, Lee, Yong‐Moon, Hong, Jin‐Tae, Yun, Yeo‐Pyo, Yoo, Hwan‐Soo

“…Obesity is a risk factor for numerous metabolic disorders such as type 2 diabetes, hypertension, and coronary heart disease. Adipocyte differentiation is…”
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Histopathologic image–based deep learning classifier for predicting platinum-based treatment responses in high-grade serous ovarian cancer by Ahn, Byungsoo, Moon, Damin, Kim, Hyun-Soo, Lee, Chung, Cho, Nam Hoon, Choi, Heung-Kook, Kim, Dongmin, Lee, Jung-Yun, Nam, Eun Ji, Won, Dongju, An, Hee Jung, Kwon, Sun Young, Shin, Su-Jin, Jung, Hye Ra, Kwon, Dohee, Park, Heejung, Kim, Milim, Cha, Yoon Jin, Park, Hyunjin, Lee, Yangkyu, Noh, Songmi, Lee, Yong-Moon, Choi, Sung-Eun, Kim, Ji Min, Sung, Sun Hee, Park, Eunhyang

“…Platinum-based chemotherapy is the cornerstone treatment for female high-grade serous ovarian carcinoma (HGSOC), but choosing an appropriate treatment for…”
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Downregulation of cell‐free miR‐198 as a diagnostic biomarker for lung adenocarcinoma‐associated malignant pleural effusion by Han, Hye‐Suk, Yun, Jieun, Lim, Sung‐nam, Han, Joung‐Ho, Lee, Ki Hyeong, Kim, Seung Taik, Kang, Min‐Ho, Son, Seung‐Myoung, Lee, Yong‐Moon, Choi, Song‐Yi, Yun, Seok Joong, Kim, Wun‐Jae, Lee, Ok‐Jun

“…Circulating cell‐free microRNAs (miRNAs) are potential cancer biomarkers. The aim of this study was to identify miRNAs that are differentially expressed…”
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Molecular subtypes of triple-negative breast cancer: understanding of subtype categories and clinical implication by Lee, Yong-Moon, Oh, Man Hwan, Go, Jai-Hyang, Han, Kyudong, Choi, Song-Yi

“…Background Triple-negative breast cancer (TNBC) is a heterogeneous entity that encompasses several subtypes with distinct molecular characteristics. The…”
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Beyond the Microscope: A Technological Overture for Cervical Cancer Detection by Lee, Yong-Moon, Lee, Boreom, Cho, Nam-Hoon, Park, Jae Hyun

“…Cervical cancer is a common and preventable disease that poses a significant threat to women's health and well-being. It is the fourth most prevalent cancer…”
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Immunohistochemical expression of CD44, matrix metalloproteinase2 and matrix metalloproteinase9 in renal cell carcinomas by Lee, Yong-Moon, Kim, Jin Man, Lee, Hyo Jin, Seong, In-Ock, Kim, Kyung-Hee

“…•CD44, MMP2 and MMP9 were positively correlated with nuclear grade in ccRCCs.•CD44 expression was correlated with shorter overall survival in ccRCC…”
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Simultaneous analysis of mono-, di-, and tri-ethanolamine in cosmetic products using liquid chromatography coupled tandem mass spectrometry by Shin, Kyong-Oh, Lee, Yong-Moon

“…Alkanolamines such as monoethanolamine (MEA), diethanolamine (DEA), and triethanolamine (TEA) are used as wetting agents in shampoos, lotions, creams, and…”
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A Bioassay Using a Pentadecanal Derivative to Measure S1P Lyase Activity by Shin, Kyong-Oh, Shamshiddinova, Maftuna, Lee, Jung-No, Lee, Kwang-Sik, Lee, Yong-Moon

“…Sphingosine-1-phosphate (S1P) is a unique lipid ligand binding to S1P receptors to transduce various cell survival or proliferation signals via small G…”
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Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate‐induced colitis in mice due to increased intestinal permeability by Kim, Ye‐Ryung, Volpert, Giora, Shin, Kyong‐Oh, Kim, So‐Yeon, Shin, Sun‐Hye, Lee, Younghay, Sung, Sun Hee, Lee, Yong‐Moon, Ahn, Jung‐Hyuck, Pewzner‐Jung, Yael, Park, Woo‐Jae, Futerman, Anthony H., Park, Joo‐Won

“…Ceramides mediate crucial cellular processes including cell death and inflammation and have recently been implicated in inflammatory bowel disease. Ceramides…”
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Exploration of Potential Breath Biomarkers of Chronic Kidney Disease through Thermal Desorption-Gas Chromatography/Mass Spectrometry by Seong, Si-Hyun, Kim, Hyun Sik, Lee, Yong-Moon, Kim, Jae-Seok, Park, Sangwoo, Oh, Jieun

“…Breath volatile organic compound (VOC) analysis is a non-invasive tool for assessing health status; the compositional profile of these compounds in the breath…”
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