Search Results - "Lee, Moon‐Hee"
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Highly selective production of succinic acid by metabolically engineered Mannheimia succiniciproducens and its efficient purification
Published in Biotechnology and bioengineering (01-10-2016)“…ABSTRACT Succinic acid (SA) is one of the fermentative products of anaerobic metabolism, and an important industrial chemical that has been much studied for…”
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Phase II Trial of Nilotinib in Patients With Metastatic Malignant Melanoma Harboring KIT Gene Aberration: A Multicenter Trial of Korean Cancer Study Group (UN10‐06)
Published in The oncologist (Dayton, Ohio) (01-11-2015)“…Background. KIT has been suggested to be a potential therapeutic target for malignant melanoma. We evaluated the antitumor activity and safety of the KIT…”
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3
A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation
Published in PloS one (18-02-2014)“…Genomic imprinting is the allele-specific expression of a gene based on parental origin. Loss of imprinting(LOI) of Insulin-like Growth Factor 2 (IGF2) during…”
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Relationship between physicians' perceived stigma toward depression and physician referral to psycho‐oncology services on an oncology/hematology ward
Published in Psycho-oncology (Chichester, England) (01-03-2018)“…Objective This study was performed to identify relationships between physicians' perceived stigma toward depression and psycho‐oncology service utilization on…”
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Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
Published in Oncoimmunology (2019)“…Changes in the immune system induced by tyrosine kinase inhibitors (TKI) have been shown to positively correlate with therapy responses in chronic myeloid…”
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Phenomenological examinations of delirium in advanced cancer patients: exploratory structural equation modelling and latent profile analysis
Published in BMC palliative care (19-10-2020)“…Background This study examined phenomenological manifestations of delirium in advanced cancer patients by examining the factor structure of the Delirium Rating…”
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7
Expanding NFκB and SUMO ties
Published in Cell cycle (Georgetown, Tex.) (01-12-2011)“…Comment on: Lee MH, et al. Mol Cell 2011; 43:180-91…”
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Multipotency and growth characteristic of periosteum-derived progenitor cells for chondrogenic, osteogenic, and adipogenic differentiation
Published in Biotechnology letters (01-04-2008)“…The mesengenic multipotency of cryopreserved periosteum-derived progenitor cells (PDPCs) for chondrogenesis, osteogenesis and adipogenesis was investigated…”
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Proteasomal dysfunction induced by 4‐hydroxy‐2,3‐trans‐nonenal, an end‐product of lipid peroxidation: a mechanism contributing to neurodegeneration?
Published in Journal of neurochemistry (01-10-2002)“…4‐Hydroxy‐2,3‐trans‐nonenal (HNE) is a neurotoxic unsaturated aldehyde end‐product of lipid peroxidation. The addition of HNE to NT‐2 and SK‐N‐MC cell lines…”
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Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6
Published in Cancer science (01-03-2010)“…(Cancer Sci 2010; 101: 793–799) Cetuximab is a monoclonal antibody targeting epidermal growth factor receptor (EGFR). The present study investigated the…”
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2,3,22,23-Tetrahydroxyl-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene, an Acyclic Triterpenoid Isolated from the Seeds of Alpinia katsumadai, Inhibits Acyl-CoA : Cholesterol Acyltransferase Activity
Published in Biological & pharmaceutical bulletin (2012)“…In order to isolate a cholesterol-lowering compound from Alpinia katsumadai, an inhibitor for acyl-CoA : cholesterol acyltransferase (ACAT), an enzyme…”
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12
Mesenchymal stromal cells for steroid-refractory acute graft-versus-host disease: a report of two cases
Published in International journal of hematology (01-07-2010)“…Severe graft-versus-host disease (GVHD) is a lethal complication of allogeneic hematopoietic stem cell transplantation (HSCT). However, there have been only a…”
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Single-cell characterization of anti-LAG-3 and anti-PD-1 combination treatment in patients with melanoma
Published in The Journal of clinical investigation (15-03-2023)“…BackgroundRelatlimab plus nivolumab (anti-lymphocyte-activation gene 3 plus anti-programmed death 1 [anti-LAG-3+anti-PD-1]) has been approved by the FDA as a…”
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14
Relative Efficacy of Checkpoint Inhibitors for Advanced NSCLC According to Programmed Death-Ligand-1 Expression: A Systematic Review and Network Meta-Analysis
Published in Scientific reports (06-08-2018)“…Although currently available immune checkpoint inhibitors with similar but slightly different indications are recommended for patients with advanced non-small…”
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Increased sFlt-1 to PlGF ratio in women who subsequently develop preeclampsia
Published in Journal of Korean medical science (01-10-2007)“…The purpose of this study was to determine whether the levels of soluble fms-like tyrosine kinase-1 (sFlt-1) and placenta growth factor (PlGF) are altered…”
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Homo-succinic acid production by metabolically engineered Mannheimia succiniciproducens
Published in Metabolic engineering (01-11-2016)“…Succinic acid (SA) is a four carbon dicarboxylic acid of great industrial interest that can be produced by microbial fermentation. Here we report development…”
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17
Spatial immunoprofiling of the intratumoral and peritumoral tissue of renal cell carcinoma patients
Published in Modern pathology (01-12-2021)“…While the abundance and phenotype of tumor-infiltrating lymphocytes are linked with clinical survival, their spatial coordination and its clinical significance…”
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The tumor and plasma cytokine profiles of renal cell carcinoma patients
Published in Scientific reports (04-08-2022)“…Renal cell carcinoma (RCC) accounts for 90% of all renal cancers and is considered highly immunogenic. Although many studies have reported the circulating…”
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Metabolic engineering of Corynebacterium glutamicum for enhanced production of 5-aminovaleric acid
Published in Microbial cell factories (07-10-2016)“…5-Aminovaleric acid (5AVA) is an important five-carbon platform chemical that can be used for the synthesis of polymers and other chemicals of industrial…”
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T and NK cell abundance defines two distinct subgroups of renal cell carcinoma
Published in Oncoimmunology (31-12-2022)“…Renal cell carcinoma (RCC) is considered as an immunogenic cancer. Because not all patients respond to current immunotherapies, we aimed to investigate the…”
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