Search Results - "Lee, M. J."

PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies by Lee, J-m., Ledermann, J.A., Kohn, E.C.

“…Poly(ADP-ribose)polymerase inhibitors (PARPis) have shown promising activity in patients with BRCA1/2 mutation-associated (BRCA1/2MUT+) ovarian and breast…”
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Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer by Liu, J.F., Barry, W.T., Birrer, M., Lee, J.-M., Buckanovich, R.J., Fleming, G.F., Rimel, B.J., Buss, M.K., Nattam, S.R., Hurteau, J., Luo, W., Curtis, J., Whalen, C., Kohn, E.C., Ivy, S.P., Matulonis, U.A.

“…Olaparib is a poly(ADP-ribose) polymerase inhibitor and cediranib is an oral anti-angiogenic. In the primary analysis of this phase II study, combination…”
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eDoctor: machine learning and the future of medicine by Handelman, G. S., Kok, H. K., Chandra, R. V., Razavi, A. H., Lee, M. J., Asadi, H.

“…Machine learning (ML) is a burgeoning field of medicine with huge resources being applied to fuse computer science and statistics to medical problems…”
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Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium‐derived cytokines expression in severe allergic asthma by Weng, C.‐M., Wang, C.‐H., Lee, M.‐J., He, J.‐R., Huang, H.‐Y., Chao, M.‐W., Chung, K. F., Kuo, H.‐P.

“…Background Exposure to environmental pollutants promotes Th2 cell responses. Aryl hydrocarbon receptor (AhR) activation aggravates allergic responses…”
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Optimal estimation retrievals of the atmospheric structure and composition of HD189733b from secondary eclipse spectroscopy by Lee, J.-M, Fletcher, L. N, Irwin, P. G. J

“…ABSTRACT Recent spectroscopic observations of transiting hot Jupiters have permitted the derivation of the thermal structure and molecular abundances of H2O,…”
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Rotation Curves in z ∼ 1-2 Star-forming Disks: Evidence for Cored Dark Matter Distributions by Genzel, R., Price, S. H., Übler, H., Förster Schreiber, N. M., Shimizu, T. T., Tacconi, L. J., Bender, R., Burkert, A., Contursi, A., Coogan, R., Davies, R. L., Davies, R. I., Dekel, A., Herrera-Camus, R., Lee, M.-J., Lutz, D., Naab, T., Neri, R., Nestor, A., Renzini, A., Saglia, R., Schuster, K., Sternberg, A., Wisnioski, E., Wuyts, S.

“…We report high-quality, H or CO rotation curves (RCs) to several Re for 41 large, massive, star-forming disk galaxies (SFGs) across the peak of cosmic galaxy…”
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Body size estimation and other psychosocial risk factors for obesity onset among US adolescents: findings from a longitudinal population level study by Liechty, J M, Lee, M-J

“…Background/Objective: The purpose of this study was to examine the longitudinal effects of body size over- and underestimation and other psychosocial factors…”
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Update on Hsp90 inhibitors in clinical trial by Kim, Y S, Alarcon, S V, Lee, S, Lee, M-J, Giaccone, G, Neckers, L, Trepel, J B

“…Twenty-five years ago the first small molecule inhibitors of Hsp90 were identified. In the intervening years there has been dramatic progress in basic…”
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The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes by Lee, M-J, Fried, S K

“…Background: Both the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR) are expressed in adipose tissue and assumed to mediate cortisol…”
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Rotation Curves in z ∼ 1–2 Star-forming Disks: Comparison of Dark Matter Fractions and Disk Properties for Different Fitting Methods by Price, S. H., Shimizu, T. T., Genzel, R., Übler, H., Förster Schreiber, N. M., Tacconi, L. J., Davies, R. I., Coogan, R. T., Lutz, D., Wuyts, S., Wisnioski, E., Nestor, A., Sternberg, A., Burkert, A., Bender, R., Contursi, A., Davies, R. L., Herrera-Camus, R., Lee, M.-J., Naab, T., Neri, R., Renzini, A., Saglia, R., Schruba, A., Schuster, K.

“…Abstract We present a follow-up analysis examining the dynamics and structures of 41 massive, large star-forming galaxies at z ∼ 0.67 − 2.45 using both ionized…”
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MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity by Lee, J.-M., Qin, C., Chai, O.H., Lan, Y., Jiang, R., Kwon, H.-J.E.

“…Tooth agenesis is a common structural birth defect in humans that results from failure of morphogenesis during early tooth development. The homeobox…”
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CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease by TARAWNEH, R, LEE, J.-M, LADENSON, J. H, MORRIS, J. C, HOLTZMAN, D. M

“…Measures of neuronal damage/dysfunction are likely good surrogates for disease progression in Alzheimer disease (AD). CSF markers of neuronal injury may offer…”
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Different functional genes of upper airway microbiome associated with natural course of childhood asthma by Kim, B.‐S., Lee, E., Lee, M.‐J., Kang, M.‐J., Yoon, J., Cho, H.‐J., Park, J., Won, S., Lee, S. Y., Hong, S. J.

“…Background Microbial colonization of the airway plays a role in the pathogenesis of asthma; however, the effect of the upper airway microbiome on childhood…”
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Clinical relevance of amnestic versus non‐amnestic mild cognitive impairment subtyping in Parkinson's disease by Chung, S. J., Park, Y.‐H., Yun, H. J., Kwon, H., Yoo, H. S., Sohn, Y. H., Lee, J.‐M., Lee, P. H.

“…Background and purpose To clarify whether subtyping of amnestic and non‐amnestic mild cognitive impairment (MCI) is clinically relevant in Parkinson's disease…”
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Constraining the atmosphere of GJ 1214b using an optimal estimation technique by Barstow, J. K., Aigrain, S., Irwin, P. G. J., Fletcher, L. N., Lee, J.-M.

“…We explore cloudy, extended H2-He atmosphere scenarios for the warm super-Earth GJ 1214b using an optimal estimation retrieval technique. This planet, orbiting…”
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Deep gray matter atrophy in neuromyelitis optica spectrum disorder and multiple sclerosis by Hyun, J.‐W., Park, G., Kwak, K., Jo, H.‐J., Joung, A., Kim, J.‐H., Lee, S. H., Kim, S., Lee, J.‐M., Kim, S.‐H., Kim, H. J.

“…Background and purpose We investigated changes in deep gray matter (DGM) volume and its relationship to cognition and clinical factors in a large cohort of…”
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The burden of white matter hyperintensities is a predictor of progressive mild cognitive impairment in patients with Parkinson's disease by Sunwoo, M. K., Jeon, S., Ham, J. H., Hong, J. Y., Lee, J. E., Lee, J.-M., Sohn, Y. H., Lee, P. H.

“…Background and purpose To evaluate whether white matter hyperintensities (WMHs) may act as an independent predictor for progression of cognitive status, the…”
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Attenuated Surface Dual Modes on Plasma Slab: Landau Damping by Pajouh, H. H., Shahmansouri, M., Lee, M.-J., Jung, Y.-D.

“…The basic features of surface dual modes are investigated on the plasma slab. The integral of kinetic wave dispersion relation is evaluated to derive the wave…”
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Physical activity, quality of life and successful ageing among community‐dwelling older adults by Choi, M., Lee, M., Lee, M.‐J., Jung, D.

“…Aim To identify the relationships between physical activity, quality of life and successful ageing among community‐dwelling older adults in South Korea…”
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Inhibitory effect of Lactobacillus salivarius on Streptococcus mutans biofilm formation by Wu, C.-C., Lin, C.-T., Wu, C.-Y., Peng, W.-S., Lee, M.-J., Tsai, Y.-C.

“…Summary Dental caries arises from an imbalance of metabolic activities in dental biofilms developed primarily by Streptococcus mutans. This study was conducted…”
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