Search Results - "Lee, Lai Yeng"
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Microencapsulation and Nanoencapsulation Using Supercritical Fluid (SCF) Techniques
Published in Pharmaceutics (05-01-2019)“…The unique properties of supercritical fluids, in particular supercritical carbon dioxide (CO₂), provide numerous opportunities for the development of…”
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Production of drug-releasing biodegradable microporous scaffold using a two-step micro-encapsulation/supercritical foaming process
Published in The Journal of supercritical fluids (01-03-2018)“…[Display omitted] •A 2-step procedure was developed to produce drug-releasing micro-porous scaffold.•Curcumin (hydrophobic drug) was encapsulated in PLGA foam…”
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3
Process Intensification Strategies and Sustainability Analysis for Amidation Processing in the Pharmaceutical Industry
Published in Industrial & engineering chemistry research (20-03-2019)“…The amidation reaction between 4-chlorobenzoyl chloride (CBC) and diisopropylamine (DIPA) has been successfully intensified with the implementation of a number…”
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Encapsulation of protein drugs in biodegradable microparticles by co-axial electrospray
Published in Journal of colloid and interface science (15-01-2008)“…A co-axial electrospray process was developed to encapsulate protein-based drugs in biodegradable polymeric microparticles eliminating the key problem faced by…”
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Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel
Published in Journal of controlled release (22-01-2008)“…Paclitaxel and poly ( l-Lactic acid) (PLA) were co-precipitated to form micro and submicron particles in a manner similar to that used in the supercritical…”
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PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: New carriers for DNA delivery
Published in Journal of controlled release (07-08-2008)“…The use of poly( D, L-lactic- co-glycolic acid) for DNA delivery application is limited by its negative surface charge and acidic degradation products. The…”
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Characterization of porous poly(D,L-lactic-co-glycolic acid) sponges fabricated by supercritical CO₂ gas-foaming method as a scaffold for three-dimensional growth of Hep3B cells
Published in Biotechnology and bioengineering (01-08-2008)“…This study presents the application of the porous poly(D,L-lactic-co-glycolic acid) (PLGA) sponges fabricated from an organic solvent free supercritical gas…”
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Mathematical modeling of mass transfer in supercritical fluid extraction of patchouli oil
Published in Engineering reports (Hoboken, N.J.) (01-11-2019)“…Patchouli oil is a high‐value essential oil used in cosmetic, food, and pharmaceutical industries. In this work, supercritical fluid extraction of patchouli…”
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9
Pneumatic transport of granular materials through a 90 ° bend
Published in Chemical engineering science (01-11-2004)“…In the present study, a pneumatic conveying system incorporating a 90 ∘ bend is investigated. This study employs the use of three non-invasive instruments to…”
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10
Lysine-based peptide-functionalized PLGA foams for controlled DNA delivery
Published in Journal of controlled release (19-08-2009)“…Due to its hydrophobicity and negatively charged surfaces, PLGA-based scaffolds have encountered problems in controlled-release and tissue engineering…”
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Jet breakup and droplet formation in near-critical regime of carbon dioxide–dichloromethane system
Published in Chemical engineering science (01-07-2008)“…The jet breakup and droplet formation mechanism of a liquid in the near-critical conditions of a solvent–antisolvent system is examined with high-speed…”
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12
Drug delivery systems for programmed and on-demand release
Published in Advanced drug delivery reviews (01-07-2018)“…With the advancement in medical science and understanding the importance of biodistribution and pharmacokinetics of therapeutic agents, modern drug delivery…”
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Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems
Published in Advanced drug delivery reviews (30-11-2006)“…This article aims to provide a comprehensive review of existing mathematical models and simulations of drug release from polymeric microspheres and of drug…”
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Techno-economic and profitability analysis of extraction of patchouli oil using supercritical carbon dioxide
Published in Journal of cleaner production (15-05-2021)“…Patchouli oil is a commercially important essential oil in the flavor and fragrance industry. In this study, a technoeconomic feasibility assessment was…”
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Optimized extraction of patchouli essential oil from Pogostemon cablin Benth. with supercritical carbon dioxide
Published in Journal of applied research on medicinal and aromatic plants (01-12-2020)“…[Display omitted] •SFE was employed on patchouli plant, including its underutilized stems, to extract patchouli oil.•Optimization of SFE was based on…”
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16
Simple Visual-Aided Automated Titration Using the Python Programming Language
Published in Journal of chemical education (10-03-2020)“…The advance of digital technology presents an opportunity to equip students with relevant skill sets as “Scientists of the Future” who are able to utilize…”
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Diphenylalanine peptide nanotubes self-assembled on functionalized metal surfaces for potential application in drug-eluting stent
Published in Journal of biomedical materials research. Part A (01-09-2016)“…This study focuses on the potential of diphenylalanine self‐assembled peptide nanotubes (FF Nts) for delivery of flufenamic acid (FA) from metal implants…”
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Covalent diphenylalanine peptide nanotube conjugated to folic acid/magnetic nanoparticles for anti-cancer drug delivery
Published in Journal of drug delivery science and technology (01-10-2017)“…Micro and nanotubes obtained from the self-assembly of diphenylalanine peptides (FNTs) were conjugated to folic acid/magnetic nanoparticles (FA/MNPs) and…”
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Teaching chemical engineering students industrial symbiosis using online resources: A Singapore case study
Published in Education for chemical engineers (01-04-2019)“…•We introduce a new teaching method using online resources (e.g. Google Maps™).•It is used to introduce the concept of industrial symbiosis (IS) to students.•A…”
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Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme
Published in Biomaterials (01-06-2009)“…Abstract Paclitaxel loaded biodegradable poly-( dl -lactic- co -glycolic) acid (PLGA) foams with microporous matrix were fabricated by a novel pressure…”
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