Search Results - "Lee, Kuan Der"
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In vitro hepatic differentiation of human mesenchymal stem cells
Published in Hepatology (Baltimore, Md.) (01-12-2004)“…This study examined whether mesenchymal stem cells (MSCs), which are stem cells originated from embryonic mesoderm, are able to differentiate into functional…”
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2
IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus
Published in Molecular cancer (05-04-2013)“…The identification of potential tumor markers can improve therapeutic planning and patient management. The aim of this study was to highlight the significance…”
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3
ER stress‐related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer
Published in Molecular oncology (01-10-2018)“…Endoplasmic reticulum (ER) stress is an adaptive response to various stress conditions and plays emerging roles in cancer. Activating transcription factor 6…”
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4
Enriched Peripheral Blood-Derived Mononuclear Cells for Treating Knee Osteoarthritis
Published in Cell transplantation (01-01-2023)“…Osteoarthritis (OA) is a common chronic skeletal disease in the elderly. There is no effective therapy to reverse disease severity and knee OA (KOA)…”
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5
Isolation of multipotent mesenchymal stem cells from umbilical cord blood
Published in Blood (01-03-2004)“…It is well accepted that umbilical cord blood has been a source for hematopoietic stem cells. However, controversy exists as to whether cord blood can serve as…”
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Accelerated Risk of Premature Ischemic Stroke in 5‐Year Survivors of Nasopharyngeal Carcinoma
Published in The oncologist (Dayton, Ohio) (01-09-2019)“…Background Research on cancer survivorship associated with nasopharyngeal carcinoma (NPC) is rare. We aimed to elucidate the risk of ischemic stroke in 5‐year…”
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Virtual Screening and In Vitro Evaluation of PD-L1 Dimer Stabilizers for Uncoupling PD-1/PD-L1 Interaction from Natural Products
Published in Molecules (Basel, Switzerland) (01-11-2020)“…Genetic mutations accumulated overtime could generate many growth and survival advantages for cancer cells, but these mutations also mark cancer cells as…”
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8
Induction of type II collagen expression in M2 macrophages derived from peripheral blood mononuclear cells
Published in Scientific reports (15-12-2022)“…The human type II collagen (Col II), specifically expressed in chondrocytes, is a crucial component of the adult hyaline cartilage. We examine the potential of…”
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9
Tumor-derived interleukin-1 receptor antagonist exhibits immunosuppressive functions and promotes pancreatic cancer
Published in Cell & bioscience (10-08-2023)“…Pancreatic ductal adenocarcinoma (PDA) is a pernicious disease characterized by an immunosuppressive milieu that is unresponsive to current immunotherapies…”
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10
Hypermethylation of the Gene Body in SRCIN1 Is Involved in Breast Cancer Cell Proliferation and Is a Potential Blood-Based Biomarker for Early Detection and a Poor Prognosis
Published in Biomolecules (Basel, Switzerland) (12-05-2024)“…Breast cancer is a leading cause of cancer mortality in women worldwide. Using the Infinium MethylationEPIC BeadChip, we analyzed plasma sample methylation to…”
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The survival impact of delayed surgery and adjuvant chemotherapy on stage II/III rectal cancer with pathological complete response after neoadjuvant chemoradiation
Published in International journal of cancer (01-04-2017)“…Neoadjuvant concurrent chemoradiation (CCRT) is standard treatment for clinical stage II/III rectal cancers. However, whether patients with pathological…”
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Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer
Published in Cancers (10-01-2023)“…MSCs are known to secrete abundant CCL2, which plays a crucial role in recruiting TAMs, promoting tumor progression. It is important to know whether disrupting…”
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Functional Network Analysis of the Transcriptomes of Mesenchymal Stem Cells Derived from Amniotic Fluid, Amniotic Membrane, Cord Blood, and Bone Marrow
Published in Stem cells (Dayton, Ohio) (01-10-2007)“…Using high‐density oligonucleotide microarrays and functional network analyses, we examined whether MSCs derived from four different origins exhibited unique…”
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14
Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression
Published in Biomedicines (13-12-2020)“…Inflammation is known to promote tumor formation and progression; however, we found a natural anti-inflammatory factor, interleukin (IL)-1 receptor antagonist…”
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Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification
Published in Biochemical pharmacology (01-10-2013)“…Oxaliplatin treatment is a mainstay of treatment for advanced gastrointestinal tract cancer, but the underlying mechanisms of acquired oxaliplatin resistance…”
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Tumor-infiltrating Leukocytes Suppress Local Inflammation Via Interleukin-1 Receptor Antagonist in a Syngeneic Prostate Cancer Model
Published in Biology (Basel, Switzerland) (31-03-2020)“…Several lines of evidence have demonstrated the tumor-promoting function of inflammation. Since many chemokines are important in coordinating immune cells…”
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Clinical assessment for non-reversal stoma and stoma re-creation after reversal surgery for patients with rectal cancer having undergoing sphincter-saving operation
Published in Asian journal of surgery (01-05-2023)“…This study aimed to identify the risk factors for permanent stoma (PS) in patients who underwent sphincter-saving operations for rectal cancer. We…”
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18
Valproic acid resensitizes cisplatin‐resistant ovarian cancer cells
Published in Cancer science (01-06-2008)“…Although certain inhibitors of histone deacetylases have been shown to induce cytotoxicity alone or in combination with chemotherapeutic agents in cancer…”
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19
The role of DNA methyltransferase 3b in esophageal squamous cell carcinoma
Published in Cancer (15-08-2012)“…BACKGROUND: The identification of potential tumor markers can improve therapeutic planning and patient management. The objective of this study was to highlight…”
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20
High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures
Published in BioMed research international (2019)“…Little is known about the function of acid-sensing ion channels (ASICs) in bone cells or osteoporotic vertebral fractures (OVF). This study delineated ASICs…”
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